Modern analytical techniques in metabolomics analysis

GC-TOF/MS-based metabolomic profiling of estrogen deficiency-induced obesity in ovariectomized rats

(2011) Bo Ma et al.   ACTA PHARMACOLOGICA SINICA

A GC/MS-based metabolomic approach for diagnosing citrin deficiency

(2011) Tomiko Kuhara et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Expanding Coverage of the Metabolome for Global Metabolite Profiling

(2011) Oscar Yanes et al.   ANALYTICAL CHEMISTRY

Deconvolution of Two-Dimensional NMR Spectra by Fast Maximum Likelihood Reconstruction: Application to Quantitative Metabolomics

(2011) Roger A. Chylla et al.   ANALYTICAL CHEMISTRY

Data Analysis Tool for Comprehensive Two-Dimensional Gas Chromatography/Time-of-Flight Mass Spectrometry

(2011) Sandra Castillo et al.   ANALYTICAL CHEMISTRY

Technical and Biological Variation in UPLC−MS-Based Untargeted Metabolic Profiling of Liver Extracts: Application in an Experimental Toxicity Study on Galactosamine

(2011) Perrine Masson et al.   ANALYTICAL CHEMISTRY

Characterization of Isotopic Abundance Measurements in High Resolution FT-ICR and Orbitrap Mass Spectra for Improved Confidence of Metabolite Identification

(2011) Ralf J. M. Weber et al.   ANALYTICAL CHEMISTRY

Potential Effect of Diaper and Cotton Ball Contamination on NMR- and LC/MS-Based Metabonomics Studies of Urine from Newborn Babies

(2011) Aaron M. Goodpaster et al.   ANALYTICAL CHEMISTRY

Cross-Platform Comparison ofCaenorhabditis elegansTissue Extraction Strategies for Comprehensive Metabolome Coverage

(2011) Florian M. Geier et al.   ANALYTICAL CHEMISTRY

Perspectives on Recent Advances in the Speed of High-Performance Liquid Chromatography

(2011) Peter W. Carr et al.   ANALYTICAL CHEMISTRY

Harnessing Metabolomics for Nutrition Research

(2011) Michael A. Zulyniak et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Practical non-targeted gas chromatography/mass spectrometry-based metabolomics platform for metabolic phenotype analysis

(2011) Hiroshi Tsugawa et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Urinary metabonomics study of anti-depressive effect of Chaihu-Shu-Gan-San on an experimental model of depression induced by chronic variable stress in rats

(2011) Zhi-Heng Su et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Potential role of metabolomics apporoaches in the area of traditional Chinese medicine: As pillars of the bridge between Chinese and Western medicine

(2011) Xijun Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Capillary electrophoresis as a metabolomics tool for non-targeted fingerprinting of biological samples

(2011) C. Barbas et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Serum 27-nor-5β-Cholestane-3,7,12,24,25 Pentol Glucuronide Discovered by Metabolomics as Potential Diagnostic Biomarker for Epithelium Ovarian Cancer

(2011) Jing Chen et al.   JOURNAL OF PROTEOME RESEARCH

Advantages of Tandem LC−MS for the Rapid Assessment of Tissue-Specific Metabolic Complexity Using a Pentafluorophenylpropyl Stationary Phase

(2011) Haitao Lv et al.   JOURNAL OF PROTEOME RESEARCH

The Human Serum Metabolome

(2011) Nikolaos Psychogios et al.   PLoS One

Metabolomic analysis of Arabidopsis reveals hemiterpenoid glycosides as products of a nitrate ion-regulated, carbon flux overflow

(2011) J. L. Ward et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiation Metabolomics. 4. UPLC-ESI-QTOFMS-Based Metabolomics for Urinary Biomarker Discovery in Gamma-Irradiated Rats

(2011) Caroline H Johnson et al.   RADIATION RESEARCH

Metabolomic investigation of cholestasis in a rat model using ultra-performance liquid chromatography/tandem mass spectrometry

(2011) Masayo Aoki et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

1 H-NMR-Based Metabolomics Study of Cerebral Infarction

(2011) Jee Youn Jung et al.   STROKE

Fourier transform mass spectrometry for metabolome analysis

(2010) C. Junot et al.   ANALYST

An optimised sample preparation method for NMR-based faecal metabonomic analysis

(2010) Junfang Wu et al.   ANALYST

Direct infusion mass spectrometry or liquid chromatography mass spectrometry for human metabonomics? A serum metabonomic study of kidney cancer

(2010) Lin Lin et al.   ANALYST

Combining metabolic fingerprinting and footprinting to understand the phenotypic response of HPV16 E6 expressing cervical carcinoma cells exposed to the HIV anti-viral drug lopinavir

(2010) Dong-Hyun Kim et al.   ANALYST

Non-invasive metabolomic analysis of breath using differential mobility spectrometry in patients with chronic obstructive pulmonary disease and healthy smokers

(2010) Maria Basanta et al.   ANALYST

Advances in NMR-based biofluid analysis and metabolite profiling

(2010) Shucha Zhang et al.   ANALYST

Ambient ionization mass spectrometry: current understanding of mechanistic theory; analytical performance and application areas

(2010) Daniel J. Weston   ANALYST

A new strategy of exploring metabolomics data using Monte Carlo tree

(2010) Dong-Sheng Cao et al.   ANALYST

High-Throughput and Multiplexed LC/MS/MRM Method for Targeted Metabolomics

(2010) Ru Wei et al.   ANALYTICAL CHEMISTRY

Optimization and Evaluation of Metabolite Extraction Protocols for Untargeted Metabolic Profiling of Liver Samples by UPLC-MS

(2010) Perrine Masson et al.   ANALYTICAL CHEMISTRY

Nontargeted Elucidation of Metabolic Pathways Using Stable-Isotope Tracers and Mass Spectrometry

(2010) Karsten Hiller et al.   ANALYTICAL CHEMISTRY

HILIC-UPLC-MS for Exploratory Urinary Metabolic Profiling in Toxicological Studies

(2010) Konstantina Spagou et al.   ANALYTICAL CHEMISTRY

Polyphenol Identification Based on Systematic and Robust High-Resolution Accurate Mass Spectrometry Fragmentation

(2010) Justin J. J. van der Hooft et al.   ANALYTICAL CHEMISTRY

Mass spectrometry–based metabolomics, analysis of metabolite-protein interactions, and imaging

(2010) Do Lee et al.   BIOTECHNIQUES

Plasma metabolic profiling of Alzheimer's disease by liquid chromatography/mass spectrometry

(2010) Nai-jing Li et al.   CLINICAL BIOCHEMISTRY

Metabolomic strategy to study therapeutic and synergistic effects of tanshinone IIA, salvianolic acid B and ginsenoside Rb1 in myocardial ischemia rats

(2010) Yonghai Lu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Thyroxine and reserpine-induced changes in metabolic profiles of rat urine and the therapeutic effect of Liu Wei Di Huang Wan detected by UPLC-HDMS

(2010) Ping Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

NMR techniques in biomedical and pharmaceutical analysis

(2010) M. Malet-Martino et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Practical Analytical Approach for the Identification of Biomarker Candidates in Prediabetic State Based upon Metabonomic Study by Ultraperformance Liquid Chromatography Coupled to Electrospray Ionization Time-of-Flight Mass Spectrometry

(2010) Haruhito Tsutsui et al.   JOURNAL OF PROTEOME RESEARCH

Integrated Ionization Approach for RRLC−MS/MS-based Metabonomics: Finding Potential Biomarkers for Lung Cancer

(2010) Zhuoling An et al.   JOURNAL OF PROTEOME RESEARCH

Liquid Chromatography−Mass Spectrometry-Based Parallel Metabolic Profiling of Human and Mouse Model Serum Reveals Putative Biomarkers Associated with the Progression of Nonalcoholic Fatty Liver Disease

(2010) Jonathan Barr et al.   JOURNAL OF PROTEOME RESEARCH

Metabonomic Study of Chinese MedicineShuanglongFormula as an Effective Treatment for Myocardial Infarction in Rats

(2010) Xiaoping Liang et al.   JOURNAL OF PROTEOME RESEARCH

Biomedical application of MALDI mass spectrometry for small-molecule analysis

(2010) Jeroen J.A. van Kampen et al.   MASS SPECTROMETRY REVIEWS

Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits

(2010) Xinjie Zhao et al.   Metabolomics

Quantitative Proteomics and Metabolomics Analysis of Normal Human Cerebrospinal Fluid Samples*

(2010) Marcel P. Stoop et al.   MOLECULAR & CELLULAR PROTEOMICS

Urinary metabonomics study in a rat model in response to protein-energy malnutrition by using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry

(2010) Zeming Wu et al.   Molecular BioSystems

Ingenuity pathways analysis of urine metabonomics phenotypes toxicity of gentamicin in multiple organs

(2010) Haitao Lv et al.   Molecular BioSystems

Urinary metabolic profiling of colorectal carcinoma based on online affinity solid phase extraction-high performance liquid chromatography and ultra performance liquid chromatography-mass spectrometry

(2010) Wenzhao Wang et al.   Molecular BioSystems

High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues

(2010) Olaf Beckonert et al.   Nature Protocols

Metabolomics: Towards Understanding Traditional Chinese Medicine

(2010) Aihua Zhang et al.   PLANTA MEDICA

Metabolomics Unravel Contrasting Effects of Biodiversity on the Performance of Individual Plant Species

(2010) Christian Scherling et al.   PLoS One

Metabolomic Analysis in Severe Childhood Pneumonia in The Gambia, West Africa: Findings from a Pilot Study

(2010) Evagelia C. Laiakis et al.   PLoS One

Prediction of metabolic fluxes by incorporating genomic context and flux-converging pattern analyses

(2010) J. M. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic profiling of murine plasma reveals an unexpected biomarker in rofecoxib-mediated cardiovascular events

(2010) J.-Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma

(2010) Elin S. Karlsson et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics

(2010) Yan Gu et al.   TALANTA

Metabonomic study on ‘Kidney-Yang Deficiency syndrome’ and intervention effects of Rhizoma Drynariae extracts in rats using ultra performance liquid chromatography coupled with mass spectrometry

(2010) Xiumei Lu et al.   TALANTA

The enhanced value of combining conventional and “omics” analyses in early assessment of drug-induced hepatobiliary injury

(2010) Heidrun Ellinger-Ziegelbauer et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Metabolomics-Based Discovery of Diagnostic Biomarkers for Onchocerciasis

(2010) Judith R. Denery et al.   PLoS Neglected Tropical Diseases

Characterizing the precision of mass-spectrometry-based metabolic profiling platforms

(2009) Age K. Smilde et al.   ANALYST

An exploratory NMR nutri-metabonomic investigation reveals dimethyl sulfone as a dietary biomarker for onion intake

(2009) Hanne Winning et al.   ANALYST

RRLC-MS/MS-based metabonomics combined with in-depth analysis of metabolic correlation network: finding potential biomarkers for breast cancer

(2009) Yanhua Chen et al.   ANALYST

Development of extractive electrospray ionization ion trap mass spectrometry for in vivo breath analysis

(2009) Jianhua Ding et al.   ANALYST

Development of a metabolomic approach based on liquid chromatography-high resolution mass spectrometry to screen for clenbuterol abuse in calves

(2009) Frédérique Courant et al.   ANALYST

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism

(2009) Pasi Soininen et al.   ANALYST

Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics

(2009) M. Brown et al.   ANALYST

Liquid chromatography-mass spectrometry methods for urinary biomarker detection in metabonomic studies with application to nutritional studies

(2009) Cristina Legido-Quigley et al.   BIOMEDICAL CHROMATOGRAPHY

Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

(2009) Yonghai Lv et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Important roles of the hyphenated HPLC-DAD-MS-SPE-NMR technique in metabonomics

(2009) Huiru Tang et al.   MAGNETIC RESONANCE IN CHEMISTRY

Metabolomic applications of HILIC-LC-MS

(2009) Simon Cubbon et al.   MASS SPECTROMETRY REVIEWS

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

(2009) Arun Sreekumar et al.   NATURE

Measurement of internal body time by blood metabolomics

(2009) Y. Minami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Acid-base-driven matrix-assisted mass spectrometry for targeted metabolomics

(2009) R. Shroff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elevated pro-inflammatory and lipotoxic mucosal lipidscharacterise irritable bowel syndrome

(2009) Kajsa Kajander et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Integrated HPLC-MS and1H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides

(2009) C. H. Johnson et al.   XENOBIOTICA

Integrated GC–MS and LC–MS plasma metabonomics analysis of ankylosing spondylitis

(2008) Peng Gao et al.   ANALYST

Microscale LC-MS-NMR Platform Applied to the Identification of Active Cyanobacterial Metabolites

(2008) Yiqing Lin et al.   ANALYTICAL CHEMISTRY

Time-resolved metabolomics reveals metabolic modulation in rice foliage

(2008) Shigeru Sato et al.   BMC Systems Biology

Alzheimer's disease beyond the genomic era: nuclear magnetic resonance (NMR) spectroscopy-based metabolomics

(2008) Ignasi Barba et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mass spectrometry for the identification of the discriminating signals from metabolomics: Current status and future trends

(2008) Erwan Werner et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Towards high-throughput metabolomics using ultrahigh-field Fourier transform ion cyclotron resonance mass spectrometry

(2008) Jun Han et al.   Metabolomics

Urine Metabolomics Analysis for Kidney Cancer Detection and Biomarker Discovery

(2008) Kyoungmi Kim et al.   MOLECULAR & CELLULAR PROTEOMICS

Marker metabolites can be therapeutic targets as well

(2008) Adrian K. Arakaki et al.   NATURE

Human metabolic phenotype diversity and its association with diet and blood pressure

(2008) Elaine Holmes et al.   NATURE

Systems biology: Metabonomics

(2008) Jeremy K. Nicholson et al.   NATURE