Impact of fluorination on proteolytic stability of peptides: a case study with α-chymotrypsin and pepsin

Impact of fluorination on proteolytic stability of peptides in human blood plasma

(2013) Vivian Asante et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A comparative protease stability study of synthetic macrocyclic peptides that mimic two endocrine hormones

(2012) John J. Ferrie et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis, Structure, and Biological Applications ofα-Fluorinatedβ-Amino Acids and Derivatives

(2012) Taryn L. March et al.   CHEMISTRY & BIODIVERSITY

Fluorine: A new element in protein design

(2012) Benjamin C. Buer et al.   PROTEIN SCIENCE

Enhanced Refoldability and Thermoactivity of Fluorinated Phosphotriesterase

(2011) Peter James Baker et al.   CHEMBIOCHEM

Fluorinated amino acids: compatibility with native protein structures and effects on protein–protein interactions

(2011) Mario Salwiczek et al.   CHEMICAL SOCIETY REVIEWS

Incorporation of Fluorinated Phenylalanine Generates Highly Specific Inhibitor of Proteasome’s Chymotrypsin-like Sites

(2010) Paul P. Geurink et al.   JOURNAL OF MEDICINAL CHEMISTRY

Crystal structure of human pepsin and its complex with pepstatin

(2010) Masao Fujinaga et al.   PROTEIN SCIENCE

Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors

(2009) Anna Łęgowska et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Positional effects of monofluorinated phenylalanines on histone acetyltransferase stability and activity

(2009) Natalya Voloshchuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Position-Dependent Effects of Fluorinated Amino Acids on the Hydrophobic Core Formation of a Heterodimeric Coiled Coil

(2009) Mario Salwiczek et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthetic therapeutic peptides: science and market

(2009) Patrick Vlieghe et al.   DRUG DISCOVERY TODAY

Fluorine in medicinal chemistry: a century of progress and a 60-year retrospective of selected highlights

(2009) Robert Filler et al.   Future Medicinal Chemistry

Protein and peptide drug delivery: Oral approaches

(2009) Jessy Shaji et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

Fluorine in Protein Environments: A QM and MD Study

(2009) Sergey A. Samsonov et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Using Fluorous Amino Acids to Modulate the Biological Activity of an Antimicrobial Peptide

(2008) Lindsey M. Gottler et al.   CHEMBIOCHEM

Discovering and improving novel peptide therapeutics

(2008) D MCGREGOR   CURRENT OPINION IN PHARMACOLOGY

Influence of Selective Fluorination on the Biological Activity and Proteolytic Stability of Glucagon-like Peptide-1

(2008) He Meng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Geometric characteristics of hydrogen bonds involving sulfur atoms in proteins

(2008) Peng Zhou et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS