Synthetic Aminoglycosides Efficiently Suppress Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations and Are Enhanced by Ivacaftor
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Synthetic Aminoglycosides Efficiently Suppress Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations and Are Enhanced by Ivacaftor
Authors
Keywords
-
Journal
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
Volume 50, Issue 4, Pages 805-816
Publisher
American Thoracic Society
Online
2013-11-19
DOI
10.1165/rcmb.2013-0282oc
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Attenuation of Nonsense-Mediated mRNA Decay Enhances In Vivo Nonsense Suppression
- (2013) Kim M. Keeling et al. PLoS One
- Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences
- (2012) Juan L. Mendoza et al. CELL
- Suppression of premature termination codons as a therapeutic approach
- (2012) Kim M. Keeling et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Ivacaftor potentiation of multiple CFTR channels with gating mutations
- (2012) Haihui Yu et al. Journal of Cystic Fibrosis
- Increased Selectivity toward Cytoplasmic versus Mitochondrial Ribosome Confers Improved Efficiency of Synthetic Aminoglycosides in Fixing Damaged Genes: A Strategy for Treatment of Genetic Diseases Caused by Nonsense Mutations
- (2012) Jeyakumar Kandasamy et al. JOURNAL OF MEDICINAL CHEMISTRY
- Development of generic immunoassay for the detection of a series of aminoglycosides with 6′-OH group for the treatment of genetic diseases in biological samples
- (2012) Moran Shalev et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- NMD: a multifaceted response to premature translational termination
- (2012) Stephanie Kervestin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A Pharmacologic Approach to Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Smoking Related Lung Disease
- (2012) Peter A. Sloane et al. PLoS One
- Regulatory domain phosphorylation to distinguish the mechanistic basis underlying acute CFTR modulators
- (2011) Louise C. Pyle et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Pharmacological Considerations for the Proper Clinical Use of Aminoglycosides
- (2011) Spyridon Pagkalis et al. DRUGS
- Chronic ataluren (PTC124) treatment of nonsense mutation cystic fibrosis
- (2011) M. Wilschanski et al. EUROPEAN RESPIRATORY JOURNAL
- Suppression of CFTR premature termination codons and rescue of CFTR protein and function by the synthetic aminoglycoside NB54
- (2011) Steven M. Rowe et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- The designer aminoglycoside NB84 significantly reduces glycosaminoglycan accumulation associated with MPS I-H in the Idua-W392X mouse
- (2011) Dan Wang et al. MOLECULAR GENETICS AND METABOLISM
- A CFTR Potentiator in Patients with Cystic Fibrosis and theG551DMutation
- (2011) Bonnie W. Ramsey et al. NEW ENGLAND JOURNAL OF MEDICINE
- Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809
- (2011) F. Van Goor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ataluren (PTC124) Induces Cystic Fibrosis Transmembrane Conductance Regulator Protein Expression and Activity in Children with Nonsense Mutation Cystic Fibrosis
- (2010) Isabelle Sermet-Gaudelus et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Repairing faulty genes by aminoglycosides: Development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations
- (2010) Igor Nudelman et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Readthrough of nonsense mutations in Rett syndrome: evaluation of novel aminoglycosides and generation of a new mouse model
- (2010) Cornelia Brendel et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- The Effect of Gentamicin-Induced Readthrough on a Novel Premature Termination Codon of CD18 Leukocyte Adhesion Deficiency Patients
- (2010) Amos J. Simon et al. PLoS One
- Production of β-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous β039 thalassemia patients
- (2009) Francesca Salvatori et al. AMERICAN JOURNAL OF HEMATOLOGY
- Poly-l-aspartic Acid Enhances and Prolongs Gentamicin-mediated Suppression of theCFTR-G542X Mutation in a Cystic Fibrosis Mouse Model
- (2009) Ming Du et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Development of Novel Aminoglycoside (NB54) with Reduced Toxicity and Enhanced Suppression of Disease-Causing Premature Stop Mutations
- (2009) Igor Nudelman et al. JOURNAL OF MEDICINAL CHEMISTRY
- Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea
- (2009) Fu-Quan Chen et al. JOURNAL OF NEUROCHEMISTRY
- Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression
- (2009) D. S. Auld et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770
- (2009) F. Van Goor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium
- (2009) Liqun Zhang et al. PLOS BIOLOGY
- Effectiveness of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a prospective phase II trial
- (2008) Eitan Kerem et al. LANCET
- PTC124 is an orally bioavailable compound that promotes suppression of the human CFTR-G542X nonsense allele in a CF mouse model
- (2008) M. Du et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started