Pharmacological Considerations for the Proper Clinical Use of Aminoglycosides

A Novel Approach to Pharmacodynamic Assessment of Antimicrobial Agents: New Insights to Dosing Regimen Design

(2011) Vincent H. Tam et al.   PLoS Computational Biology

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Amikacin Monotherapy for Sepsis Caused by Panresistant Pseudomonas aeruginosa

(2010) B. Layeux et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and Spectrum of the Neoglycoside ACHN-490

(2010) J. B. Aggen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tobramycin disposition in ICU patients receiving a once daily regimen: population approach and dosage simulations

(2010) Jean-Marie Conil et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

High-level antibiotic resistance in Pseudomonas aeruginosa biofilm: the ndvB gene is involved in the production of highly glycerol-phosphorylated  -(1->3)-glucans, which bind aminoglycosides

(2010) I. Sadovskaya et al.   GLYCOBIOLOGY

Competitive antagonism of fluorescent gentamicin uptake in the cochlea

(2010) Qi Wang et al.   HEARING RESEARCH

Once versus multiple daily dosing of aminoglycosides for patients with febrile neutropenia: a systematic review and meta-analysis

(2010) M. N. Mavros et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Chip Calorimetry for Fast and Reliable Evaluation of Bactericidal and Bacteriostatic Treatments of Biofilms

(2009) F. Buchholz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Developmental Pharmacokinetics of Gentamicin in Preterm and Term Neonates

(2009) Elisabet I. Nielsen et al.   CLINICAL PHARMACOKINETICS

Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways

(2009) Kelly N. Owens et al.   HEARING RESEARCH

Bismuth–thiol incorporation enhances biological activities of liposomal tobramycin against bacterial biofilm and quorum sensing molecules production by Pseudomonas aeruginosa

(2009) Majed Halwani et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Eight years' experience of an extended-interval dosing protocol for gentamicin in neonates

(2009) E. J. Begg et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Role of persisters and small-colony variants in antibiotic resistance of planktonic and biofilm-associated Staphylococcus aureus: an in vitro study

(2009) R. Singh et al.   JOURNAL OF MEDICAL MICROBIOLOGY

A role for sigma factor B in the emergence of Staphylococcus aureus small-colony variants and elevated biofilm production resulting from an exposure to aminoglycosides

(2009) Gabriel Mitchell et al.   MICROBIAL PATHOGENESIS

Once-Daily Gentamicin Dosing in Children with Febrile Neutropenia Resulting from Antineoplastic Therapy

(2009) Miriam Inparajah et al.   PHARMACOTHERAPY

Targeting a bacterial stress response to enhance antibiotic action

(2009) S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treatment of early Pseudomonas aeruginosa infection in patients with cystic fibrosis: the ELITE trial

(2009) F. Ratjen et al.   THORAX

Synergistic ototoxicity due to noise exposure and aminoglycoside antibiotics

(2009) PeterS Steyger et al.   Noise & Health

Pharmacodynamic Modeling of Aminoglycosides against Pseudomonas aeruginosa and Acinetobacter baumannii: Identifying Dosing Regimens To Suppress Resistance Development

(2008) V. H. Tam et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Treatment of osteomyelitis by liposomal gentamicin-impregnated calcium sulfate

(2008) Tang Hui et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

Potential of old-generation antibiotics to address current need for new antibiotics

(2008) Matthew E Falagas et al.   Expert Review of Anti-Infective Therapy

Do we still need the aminoglycosides?

(2008) Emanuele Durante-Mangoni et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Antimicrobial breakpoints for Gram-negative aerobic bacteria based on pharmacokinetic–pharmacodynamic models with Monte Carlo simulation

(2008) Christopher R. Frei et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Distribution, Organization, and Ecology of Bacteria in Chronic Wounds

(2008) K. Kirketerp-Moller et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The Neglected Intrinsic Resistome of Bacterial Pathogens

(2008) Alicia Fajardo et al.   PLoS One

Suboptimal Aminoglycoside Dosing in Critically Ill Patients

(2008) Rhonda S Rea et al.   THERAPEUTIC DRUG MONITORING

Aminoglycoside induced ototoxicity

(2008) O’neil W. Guthrie   TOXICOLOGY