Article
Nutrition & Dietetics
Arick Wang, Charles E. Rose, Yan Ping Qi, Jennifer L. Williams, Christine M. Pfeiffer, Krista S. Crider
Summary: The analysis of NHANES data from 2011-2018 found no significant impact of voluntary fortification of corn masa flour on the folate levels of Hispanic women of reproductive age, although there was a significant increase in RBC folate concentration among lesser acculturated Hispanic women consuming ECGP only.
Letter
Medicine, General & Internal
Steven Woloshin, Barnett S. Kramer
Summary: This article discusses the role and limitations of graphs, as well as how to avoid being misled by them. It also mentions a recent journal article that featured a graph considered to be misleading.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Nutrition & Dietetics
Flinle Danielle Biemi, Vijay Ganji
Summary: There were no significant differences in anemia and markers of anemia between pre- and post-fortification periods in children in Ivory Coast, but the mean corpuscular volume significantly increased in the post-fortification period. The lack of significant differences in anemia indicators between the two periods requires further investigation.
Article
Public, Environmental & Occupational Health
Jolieke C. van der Pols, Peter Baade, Lauren B. Spencer
Summary: The study found that the colorectal cancer incidence in Australia generally decreased after the mandatory fortification of bread flour with folic acid in 2009.
PUBLIC HEALTH NUTRITION
(2021)
Review
Nutrition & Dietetics
Carolyn Ledowsky, Abela Mahimbo, Vanessa Scarf, Amie Steel
Summary: Women of childbearing age and pregnant women in high-income countries do not get sufficient folate intake from food sources alone and need to take folic acid supplements. However, most women taking folic acid supplements exceed the upper tolerable limit. Therefore, the recommendations and upper tolerable limit for folic acid supplements need to be reevaluated.
Article
Multidisciplinary Sciences
Anteneh Berhane, Tefera Belachew
Summary: This study aims to estimate the trend and burden of neural tube defects in Eastern Ethiopia and investigate the epidemiological implications of the findings. The study found an increasing trend and burden of neural tube defects, with insignificant importance of preconception folic acid supplementation in the region. Therefore, it is recommended to consider preconception folic acid supplementation in conjunction with healthcare services to reduce the risk of neural tube defects in the region.
Article
Chemistry, Applied
Rhowell N. Tiozon, Drexel H. Camacho, Aldrin P. Bonto, Glenn G. Oyong, Nese Sreenivasulu
Summary: The study demonstrated an efficient process of rice fortification through ultrasonic treatment and absorption of folic acid, which significantly increased the folate intake in rice. The fortified brown rice showed improved textural properties that are favorable for consumers.
Article
Nutrition & Dietetics
Josiane Steluti, Andreia Machado Miranda, Eduardo De Carli, Cecilia Zanin Palchetti, Regina Mara Fisberg, Dirce Maria Lobo Marchioni
Summary: A study in São Paulo City, Brazil, investigated the association between inflammatory markers and unmetabolized folic acid (UMFA) in a population exposed to mandatory fortification. The results showed that higher UMFA concentrations were linked to lower levels of proinflammatory markers like TNF-alpha, IL-1 beta, and IL-12. This suggests a connection between folate metabolism and inflammatory status in adults.
EUROPEAN JOURNAL OF NUTRITION
(2021)
Review
Food Science & Technology
Shrooq Ismail, Sereen Eljazzar, Vijay Ganji
Summary: Inadequate folate intake during pregnancy is the leading cause of neural tube defects (NTDs) in newborns. The mandatory fortification of folic acid in processed cereals in the US has decreased the prevalence of NTDs and also had unintended benefits such as reducing anemia and the risk of cardiovascular diseases. However, there are potential issues with folic acid fortification that need to be monitored, such as the presence of unmetabolized folic acid and increased risk of cancer.
Article
Food Science & Technology
Noer Abyor Handayani, Kamarza Mulia, Sutrasno Kartohardjono, Elsa Anisa Krisanti
Summary: Spray-dried chitosan microparticles fortified jelly foods were found to increase the bioavailability of iron and folic acid, which could help alleviate iron deficiency anaemia and folic acid deficiency anaemia.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Article
Nutrition & Dietetics
Khadijah Alnabbat, Ali M. Fardous, Aiman Shahab, Andrew A. James, Manhel R. Bahry, Ahmad R. Heydari
Summary: This study found that high consumption of folic acid from fortified foods can lead to genomic instability in peripheral lymphocytes, which is consistent with previous reports.
Article
Nutrition & Dietetics
Cecilia Zanin Palchetti, Josiane Steluti, Eliseu Verly-Jr, Eduardo De Carli, Rosely Sichieri, Edna Massae Yokoo, Rosangela Alves Pereira, Dirce Maria Lobo Marchioni
Summary: The study compared the evolution of dietary folate intake in the Brazilian population in two post-fortification periods, estimating the prevalence of folate inadequacy (POFI) and the contribution of food groups to folate intake. Despite mandatory folic acid flour fortification in Brazil for nearly two decades, an increase in POFI was observed in 2017-2018. This study provides important scientific information to guide public health fortification strategies.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Lola Madrid, Kartavya J. Vyas, Vijaya Kancherla, Haleluya Leulseged, Parminder S. Suchdev, Quique Bassat, Samba Sow, Shams El Arifeen, ShabirA Madhi, Dickens Onyango, Ikechukwu Ogbuanu, J. Anthony G. Scott, Dianna Blau, Inacio Mandomando, Adama M. Keita, Emily S. Gurley, Sana Mahtab, Victor Akelo, Sulaiman Sannoh, Yenenesh Tilahun, Rosauro Varo, Uma Onwuchekwa, Afruna Rahman, Yasmin Adam, Richard Omore, Sandra Lako, Elisio Xerinda, Kazi Munisul Islam, Amy Wise, Beth A. Tippet-Barr, Erick Kaluma, Sara Ajanovic, Karen L. Kotloff, Mohammad Zahid Hossain, Portia Mutevedzi, Milagritos Tapia, Emily Rogena, Francis Moses, Cynthia G. Whitney, Nega Assefa
Summary: This study aimed to estimate the mortality attributed to neural tube defects in seven countries in sub-Saharan Africa and southeast Asia. The results showed that neural tube defects were a common cause of stillbirth and neonatal deaths, especially in Ethiopia. Therefore, implementing necessary interventions such as mandatory folic acid fortification could reduce mortality due to neural tube defects.
LANCET GLOBAL HEALTH
(2023)
Article
Food Science & Technology
Anna W. Waller, Marcela Gaytan-Martinez, Juan E. Andrade Laborde
Summary: This study validated a paper-based, smartphone-assisted colorimetric assay (Nu3Px) for determining the iron content in fortified flours compared to the gold standard method, atomic emission spectrometry (AES). The results showed that Nu3Px had good error parameters and similar classifications to AES, and using affordable sampling tools also yielded accurate results.
Article
Nutrition & Dietetics
Fenglei Wang, Kana Wu, Yanping Li, Rui Song, You Wu, Xuehong Zhang, Mingyang Song, Liming Liang, Stephanie A. Smith-Warner, Edward L. Giovannucci, Walter C. Willett
Summary: The study aimed to examine the association between folate intake in different chemical forms and colorectal cancer risk, especially in the postfortification era in the United States. The results showed that both total folate intake and synthetic folic acid intake were associated with a lower risk of colorectal cancer after long latency periods. High folate intake in the postfortification period was not related to increased colorectal cancer risk in the US female population.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
