Sex Affects Bone Morphogenetic Protein Type II Receptor Signaling in Pulmonary Artery Smooth Muscle Cells

Sex-Dependent Influence of Endogenous Estrogen in Pulmonary Hypertension

(2014) Kirsty M. Mair et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy

(2014) Daisuke Nakada et al.   NATURE

Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells

(2013) Jun Yang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Imatinib Attenuates Hypoxia-induced Pulmonary Arterial Hypertension Pathology via Reduction in 5-Hydroxytryptamine through Inhibition of Tryptophan Hydroxylase 1 Expression

(2013) Loredana Ciuclan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Correction of NonsenseBMPR2andSMAD9Mutations by Ataluren in Pulmonary Arterial Hypertension

(2013) Kylie M. Drake et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension

(2013) Yvonne Dempsie et al.   CARDIOVASCULAR RESEARCH

SMAD1 Deficiency in Either Endothelial or Smooth Muscle Cells Can Predispose Mice to Pulmonary Hypertension

(2013) Chul Han et al.   HYPERTENSION

Pulmonary Arterial Hypertension

(2013) Michael D. McGoon et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Endoglin-Mediated Suppression of Prostate Cancer Invasion Is Regulated by Activin and Bone Morphogenetic Protein Type II Receptors

(2013) Michael J. Breen et al.   PLoS One

17β-Estradiol Attenuates Hypoxic Pulmonary Hypertension via Estrogen Receptor–mediated Effects

(2012) Tim Lahm et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Activity of the Estrogen-Metabolizing Enzyme Cytochrome P450 1B1 Influences the Development of Pulmonary Arterial Hypertension

(2012) Kevin White et al.   CIRCULATION

Gene Therapy by Targeted Adenovirus-mediated Knockdown of Pulmonary Endothelial Tph1 Attenuates Hypoxia-induced Pulmonary Hypertension

(2012) Ian Morecroft et al.   MOLECULAR THERAPY

Antagonism of Inhibitor of Apoptosis Proteins Increases Bone Metastasis via Unexpected Osteoclast Activation

(2012) Chang Yang et al.   Cancer Discovery

BMPR2 expression is suppressed by signaling through the estrogen receptor

(2012) Eric D Austin et al.   Biology of Sex Differences

Estrogen-mediated epigenetic repression of the imprinted gene cyclin-dependent kinase inhibitor 1C in breast cancer cells

(2011) Benjamin A.T. Rodriguez et al.   CARCINOGENESIS

Sex Differences in the Diagnosis, Treatment, and Outcome of Patients With Pulmonary Arterial Hypertension Enrolled in the Registry to Evaluate Early and Long-term Pulmonary Arterial Hypertension Disease Management

(2011) Shelley Shapiro et al.   CHEST

Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH

(2011) Kevin White et al.   PHYSIOLOGICAL GENOMICS

The serotonin transporter, gender, and 17  oestradiol in the development of pulmonary arterial hypertension

(2010) K. White et al.   CARDIOVASCULAR RESEARCH

Genetic Risk Factors for Portopulmonary Hypertension in Patients with Advanced Liver Disease

(2009) Kari E. Roberts et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension

(2009) I. Morecroft et al.   CARDIOVASCULAR RESEARCH

Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females

(2009) E. D. Austin et al.   EUROPEAN RESPIRATORY JOURNAL

Bone morphogenetic protein receptors and signal transduction

(2009) K. Miyazono et al.   JOURNAL OF BIOCHEMISTRY

Genetics and Genomics of Pulmonary Arterial Hypertension

(2009) Rajiv D. Machado et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Platelet-derived Growth Factor Expression and Function in Idiopathic Pulmonary Arterial Hypertension

(2008) Frédéric Perros et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Gene expression in BMPR2 mutation carriers with and without evidence of Pulmonary Arterial Hypertension suggests pathways relevant to disease penetrance

(2008) James West et al.   BMC Medical Genomics

Pulmonary hypertension: therapeutic targets within the serotonin system

(2008) Y Dempsie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Converging Evidence in Support of the Serotonin Hypothesis of Dexfenfluramine-Induced Pulmonary Hypertension With Novel Transgenic Mice

(2008) Yvonne Dempsie et al.   CIRCULATION

Mutations in Bone Morphogenetic Protein Type II Receptor Cause Dysregulation of Id Gene Expression in Pulmonary Artery Smooth Muscle Cells

(2008) Jun Yang et al.   CIRCULATION RESEARCH

An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension

(2008) Georg Hansmann et al.   JOURNAL OF CLINICAL INVESTIGATION