Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension

17β-Estradiol Attenuates Hypoxic Pulmonary Hypertension via Estrogen Receptor–mediated Effects

(2012) Tim Lahm et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Activity of the Estrogen-Metabolizing Enzyme Cytochrome P450 1B1 Influences the Development of Pulmonary Arterial Hypertension

(2012) Kevin White et al.   CIRCULATION

Pulmonary hypertension associated with benfluorex exposure

(2012) Laurent Savale et al.   EUROPEAN RESPIRATORY JOURNAL

Testosterone negatively regulates right ventricular load stress responses in mice

(2012) Anna R. Hemnes et al.   Pulmonary Circulation

Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension

(2011) Jennifer A. Johnson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Serotonin transporter, sex, and hypoxia: microarray analysis in the pulmonary arteries of mice identifies genes with relevance to human PAH

(2011) Kevin White et al.   PHYSIOLOGICAL GENOMICS

Altered Gene Expression in Pulmonary Tissue of Tryptophan Hydroxylase-1 Knockout Mice: Implications for Pulmonary Arterial Hypertension

(2011) Richard B. Rothman et al.   PLoS One

Adiponectin Decreases Pulmonary Arterial Remodeling in Murine Models of Pulmonary Hypertension

(2010) Meiqian Weng et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The serotonin transporter, gender, and 17  oestradiol in the development of pulmonary arterial hypertension

(2010) K. White et al.   CARDIOVASCULAR RESEARCH

Cytochrome P450 1B1 Contributes to Angiotensin II–Induced Hypertension and Associated Pathophysiology

(2010) Brett L. Jennings et al.   HYPERTENSION

Cytochrome P450 1B1 Gene Polymorphisms as Predictors of Anticancer Drug Activity: Studies with In vitro Models

(2010) A. Laroche-Clary et al.   MOLECULAR CANCER THERAPEUTICS

In vivo effects of a combined 5-HT1B receptor/SERT antagonist in experimental pulmonary hypertension

(2009) I. Morecroft et al.   CARDIOVASCULAR RESEARCH

Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females

(2009) E. D. Austin et al.   EUROPEAN RESPIRATORY JOURNAL

Gene expression in BMPR2 mutation carriers with and without evidence of Pulmonary Arterial Hypertension suggests pathways relevant to disease penetrance

(2008) James West et al.   BMC Medical Genomics

Pulmonary hypertension: therapeutic targets within the serotonin system

(2008) Y Dempsie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Converging Evidence in Support of the Serotonin Hypothesis of Dexfenfluramine-Induced Pulmonary Hypertension With Novel Transgenic Mice

(2008) Yvonne Dempsie et al.   CIRCULATION