Hyperhomocysteinemia attenuates angiogenesis through reduction of HIF-1α and PGC-1α levels in muscle fibers during hindlimb ischemia

Defective Homocysteine Metabolism: Potential Implications for Skeletal Muscle Malfunction

(2013) Sudhakar Veeranki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification and Validation of Novel Contraction-Regulated Myokines Released from Primary Human Skeletal Muscle Cells

(2013) Silja Raschke et al.   PLoS One

Skeletal Muscle–Specific Genetic Determinants Contribute to the Differential Strain-Dependent Effects of Hindlimb Ischemia in Mice

(2012) Joseph M. McClung et al.   AMERICAN JOURNAL OF PATHOLOGY

Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia

(2012) Utpal Sen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

VEGF Improves Skeletal Muscle Regeneration After Acute Trauma and Reconstruction of the Limb in a Rabbit Model

(2012) Soenke Percy Frey et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Homocysteine, Frailty, and All-Cause Mortality in Older Men: The Health in Men Study

(2012) Y. Y. E. Wong et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Hypoxia Inducible Factor 1-Alpha (HIF-1 Alpha) Is Induced during Reperfusion after Renal Ischemia and Is Critical for Proximal Tubule Cell Survival

(2012) Elisa Conde et al.   PLoS One

Mitochondrial division/mitophagy inhibitor (Mdivi) Ameliorates Pressure Overload Induced Heart Failure

(2012) Srikanth Givvimani et al.   PLoS One

PKB signaling and atrogene expression in skeletal muscle of aged mice

(2011) Megan Gaugler et al.   JOURNAL OF APPLIED PHYSIOLOGY

Skeletal Muscle-Specific Expression of PGC-1α-b, an Exercise-Responsive Isoform, Increases Exercise Capacity and Peak Oxygen Uptake

(2011) Miki Tadaishi et al.   PLoS One

Vascular complications of cystathionine β-synthase deficiency: future directions for homocysteine-to-hydrogen sulfide research

(2010) Richard S. Beard et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hypoxia induces PGC-1α expression and mitochondrial biogenesis in the myocardium of TOF patients

(2010) Lingyun Zhu et al.   CELL RESEARCH

Homocysteine impaired endothelial function through compromised vascular endothelial growth factor/Akt/endothelial nitric oxide synthase signalling

(2010) Ting-Ting Yan et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Cystathionine γ-Lyase-deficient Mice Require Dietary Cysteine to Protect against Acute Lethal Myopathy and Oxidative Injury

(2010) Isao Ishii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

X-ray imaging of differential vascular density in MMP-9−/−, PAR-1−/+, hyperhomocysteinemic (CBS−/+) and diabetic (Ins2−/+) mice

(2010) S. Givvimani et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Homocysteine and Peripheral Arterial Disease: Systematic Review and Meta-analysis

(2009) N. Khandanpour et al.   EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY

Muscle-specific VEGF deficiency greatly reduces exercise endurance in mice

(2009) I. Mark Olfert et al.   JOURNAL OF PHYSIOLOGY-LONDON

Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia

(2009) Anne Limbourg et al.   Nature Protocols

Adenoviral transfer of HIF-1  enhances vascular responses to critical limb ischemia in diabetic mice

(2009) K. Sarkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Treatment of Hyperhomocysteinemia

(2008) Bradley A. Maron et al.   Annual Review of Medicine

Vascular endothelial growth factor-D transgenic mice show enhanced blood capillary density, improved postischemic muscle regeneration, and increased susceptibility to tumor formation

(2008) A.-M. Karkkainen et al.   BLOOD

The Akt/mTOR Pathway Assures the Synthesis of HIF-1α Protein in a Glucose- and Reoxygenation-dependent Manner in Irradiated Tumors

(2008) Hiroshi Harada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK regulates basal skeletal muscle capillarization and VEGF expression, but is not necessary for the angiogenic response to exercise

(2008) Kevin A. Zwetsloot et al.   JOURNAL OF PHYSIOLOGY-LONDON

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE