Reduction of endoplasmic reticulum stress by 4-phenylbutyric acid prevents the development of hypoxia-induced pulmonary arterial hypertension

Imatinib Attenuates Hypoxia-induced Pulmonary Arterial Hypertension Pathology via Reduction in 5-Hydroxytryptamine through Inhibition of Tryptophan Hydroxylase 1 Expression

(2013) Loredana Ciuclan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of Src Tyrosine Kinases in Experimental Pulmonary Hypertension

(2012) Soni Savai Pullamsetti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hypoxia induces unique proliferative response in adventitial fibroblasts by activating PDGFβ receptor-JNK1 signalling

(2012) Evgeniy Panzhinskiy et al.   CARDIOVASCULAR RESEARCH

Platelet-derived growth factor (PDGF) induces pulmonary vascular remodeling through 15-LO/15-HETE pathway under hypoxic condition

(2012) Lei Zhang et al.   CELLULAR SIGNALLING

Histone Deacetylation Inhibition in Pulmonary Hypertension

(2012) Lan Zhao et al.   CIRCULATION

Attenuating Endoplasmic Reticulum Stress as a Novel Therapeutic Strategy in Pulmonary Hypertension

(2012) Peter Dromparis et al.   CIRCULATION

Loss of Adenomatous Poliposis Coli-α3 Integrin Interaction Promotes Endothelial Apoptosis in Mice and Humans

(2012) Vinicio A. de Jesus Perez et al.   CIRCULATION RESEARCH

PAR-2 Inhibition Reverses Experimental Pulmonary Hypertension

(2012) Grazyna Kwapiszewska et al.   CIRCULATION RESEARCH

Cytoprotective regulation of the mitochondrial permeability transition pore is impaired in type 2 diabetic Goto–Kakizaki rat hearts

(2012) Takahito Itoh et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Role of ER Stress in Ventricular Contractile Dysfunction in Type 2 Diabetes

(2012) Akifumi Takada et al.   PLoS One

Meta-Analysis of Monotherapy Versus Combination Therapy for Pulmonary Arterial Hypertension

(2011) Benjamin D. Fox et al.   AMERICAN JOURNAL OF CARDIOLOGY

Validation of the Pulmonary Hypertension Connection Equation for Survival Prediction in Pulmonary Arterial Hypertension

(2011) Thenappan Thenappan et al.   CHEST

The ER stress factor XBP1s prevents amyloid-β neurotoxicity

(2011) Sergio Casas-Tinto et al.   HUMAN MOLECULAR GENETICS

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress

(2011) Brian F. Teske et al.   MOLECULAR BIOLOGY OF THE CELL

Mechanisms of disease: pulmonary arterial hypertension

(2011) Ralph T. Schermuly et al.   Nature Reviews Cardiology

The Role of Nogo and the Mitochondria-Endoplasmic Reticulum Unit in Pulmonary Hypertension

(2011) G. Sutendra et al.   Science Translational Medicine

Imatinib in Pulmonary Arterial Hypertension Patients with Inadequate Response to Established Therapy

(2010) Hossein A. Ghofrani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Basic Science of Pulmonary Arterial Hypertension for Clinicians

(2010) Stephen L. Archer et al.   CIRCULATION

Signaling cell death from the endoplasmic reticulum stress response

(2010) Gordon C Shore et al.   CURRENT OPINION IN CELL BIOLOGY

Pulmonary arterial hypertension: from the kingdom of the near-dead to multiple clinical trial meta-analyses

(2010) N. Galie et al.   EUROPEAN HEART JOURNAL

Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization

(2009) C. Guignabert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A meta-analysis of randomized controlled trials in pulmonary arterial hypertension

(2009) N. Galie et al.   EUROPEAN HEART JOURNAL

The Role of NADPH Oxidase in Chronic Intermittent Hypoxia-Induced Pulmonary Hypertension in Mice

(2008) Rachel E. Nisbet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Molecular pathogenesis of pulmonary arterial hypertension

(2008) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE