The value of experimental models of colitis in predicting efficacy of biological therapies for inflammatory bowel diseases
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Title
The value of experimental models of colitis in predicting efficacy of biological therapies for inflammatory bowel diseases
Authors
Keywords
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Journal
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
Volume 305, Issue 11, Pages G763-G785
Publisher
American Physiological Society
Online
2013-08-30
DOI
10.1152/ajpgi.00004.2013
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Note: Only part of the references are listed.- A Randomized Controlled Trial of the Efficacy and Safety of CCX282-B, an Orally-Administered Blocker of Chemokine Receptor CCR9, for Patients with Crohn’s Disease
- (2013) Satish Keshav et al. PLoS One
- Mo2083 A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of AMG 827 in Subjects With Moderate to Severe Crohn's Disease
- (2012) Stephan R. Targan et al. GASTROENTEROLOGY
- Abatacept for Crohn's Disease and Ulcerative Colitis
- (2012) William J. Sandborn et al. GASTROENTEROLOGY
- A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis
- (2012) Paul J Rutgeerts et al. GUT
- Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial
- (2012) Wolfgang Hueber et al. GUT
- Why study animal models of IBD?
- (2012) Warren Strober INFLAMMATORY BOWEL DISEASES
- Microbial and Histopathologic Considerations in the Use of Mouse Models of Inflammatory Bowel Diseases
- (2012) Trenton R. Schoeb et al. INFLAMMATORY BOWEL DISEASES
- Exclusive antagonism of the α4β7 integrin by vedolizumab confirms the gut-selectivity of this pathway in primates
- (2012) Eric R. Fedyk et al. INFLAMMATORY BOWEL DISEASES
- Efficacy, safety and tolerability of vidofludimus in patients with inflammatory bowel disease: The ENTRANCE study
- (2012) K.R. Herrlinger et al. Journal of Crohns & Colitis
- Host-dependent control of early regulatory and effector T-cell differentiation underlies the genetic susceptibility of RAG2-deficient mouse strains to transfer colitis
- (2012) V Valatas et al. Mucosal Immunology
- Tofacitinib, an Oral Janus Kinase Inhibitor, in Active Ulcerative Colitis
- (2012) William J. Sandborn et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ustekinumab Induction and Maintenance Therapy in Refractory Crohn's Disease
- (2012) William J. Sandborn et al. NEW ENGLAND JOURNAL OF MEDICINE
- Risk of Natalizumab-Associated Progressive Multifocal Leukoencephalopathy
- (2012) Gary Bloomgren et al. NEW ENGLAND JOURNAL OF MEDICINE
- Overview of the biology of type I interferons
- (2012) George D Kalliolias et al. ARTHRITIS RESEARCH & THERAPY
- Review article: defining remission in ulcerative colitis
- (2011) S. P. L. Travis et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Efficacy of Biological Therapies in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis
- (2011) Alexander C Ford et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- IL-10–Producing Regulatory B10 Cells Inhibit Intestinal Injury in a Mouse Model
- (2011) Koichi Yanaba et al. AMERICAN JOURNAL OF PATHOLOGY
- NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
- (2011) Eran Elinav et al. CELL
- Proinflammatory Cytokines in the Pathogenesis of Inflammatory Bowel Diseases
- (2011) Warren Strober et al. GASTROENTEROLOGY
- The Membrane-Bound Mucin Muc1 Regulates T Helper 17-Cell Responses and Colitis in Mice
- (2011) Atsushi Nishida et al. GASTROENTEROLOGY
- B Cells That Produce Immunoglobulin E Mediate Colitis in BALB/c Mice
- (2011) Jennifer C. Hoving et al. GASTROENTEROLOGY
- New therapies for inflammatory bowel disease: from the bench to the bedside
- (2011) Silvio Danese GUT
- Randomised placebo-controlled trial of rituximab (anti-CD20) in active ulcerative colitis
- (2011) K. Leiper et al. GUT
- The mucosal addressin cell adhesion molecule antibody PF-00547,659 in ulcerative colitis: a randomised study
- (2011) S. Vermeire et al. GUT
- The interleukin-17 cytokine family: critical players in host defence and inflammatory diseases
- (2011) Rajita Pappu et al. IMMUNOLOGY
- Pharmacological intervention studies using mouse models of the inflammatory bowel diseases
- (2011) Iurii Koboziev et al. INFLAMMATORY BOWEL DISEASES
- Toll-like receptor-7 ligand imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis
- (2011) Satheesh K. Sainathan et al. INFLAMMATORY BOWEL DISEASES
- Vedolizumab for the Treatment of Active Ulcerative Colitis: A Randomized Controlled Phase 2 Dose-ranging Study
- (2011) Asit Parikh et al. INFLAMMATORY BOWEL DISEASES
- Autoimmunity and inflammation: murine models and translational studies
- (2011) Samuel W. Hall et al. MAMMALIAN GENOME
- Intestinal homeostasis and its breakdown in inflammatory bowel disease
- (2011) Kevin J. Maloy et al. NATURE
- Genetics and pathogenesis of inflammatory bowel disease
- (2011) Bernard Khor et al. NATURE
- CCL25/CCR9 Interactions Regulate Large Intestinal Inflammation in a Murine Model of Acute Colitis
- (2011) Marc-Andre Wurbel et al. PLoS One
- Localized Delivery of Interferon-β by Lactobacillus Exacerbates Experimental Colitis
- (2011) Adelle P. McFarland et al. PLoS One
- Interferon-β exacerbates Th17-mediated inflammatory disease
- (2011) Robert C. Axtell et al. TRENDS IN IMMUNOLOGY
- The Nlrp3 inflammasome: contributions to intestinal homeostasis
- (2011) Md. Hasan Zaki et al. TRENDS IN IMMUNOLOGY
- Evaluation of therapeutic targets in animal models of arthritis: How does it relate to rheumatoid arthritis?
- (2010) Lisette Bevaart et al. ARTHRITIS AND RHEUMATISM
- Interleukin-11 Reduces TLR4-Induced Colitis in TLR2-Deficient Mice and Restores Intestinal STAT3 Signaling
- (2010) Deanna L. Gibson et al. GASTROENTEROLOGY
- Colitis and Intestinal Inflammation in IL10−/− Mice Results From IL-13Rα2–Mediated Attenuation of IL-13 Activity
- (2010) Mark S. Wilson et al. GASTROENTEROLOGY
- Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study
- (2010) Christopher D. Williams et al. GASTROENTEROLOGY
- Suppression of inflammation in ulcerative colitis by interferon- -1a is accompanied by inhibition of IL-13 production
- (2010) P. J. Mannon et al. GUT
- Anti-CD3 antibody visilizumab is not effective in patients with intravenous corticosteroid-refractory ulcerative colitis
- (2010) W. J. Sandborn et al. GUT
- The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
- (2010) Md. Hasan Zaki et al. IMMUNITY
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- (2010) Jeremy Dupaul-Chicoine et al. IMMUNITY
- Influences of Intestinal Bacteria in Human Inflammatory Bowel Disease
- (2010) Rachel Vanderploeg et al. INFECTIOUS DISEASE CLINICS OF NORTH AMERICA
- Case Series: Ulcerative Colitis, Multiple Sclerosis, and Interferon-Beta 1a
- (2010) S. Rodrigues et al. INFLAMMATORY BOWEL DISEASES
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- (2010) Janneke C. van der Woude et al. INFLAMMATORY BOWEL DISEASES
- 4SC-101, a novel immunosuppressive drug, inhibits IL-17 and attenuates colitis in two murine models of inflammatory bowel disease†
- (2010) Leo R. Fitzpatrick et al. INFLAMMATORY BOWEL DISEASES
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- (2010) Ailsa L. Hart et al. INFLAMMATORY BOWEL DISEASES
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- (2010) Robert M. Plenge et al. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
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- (2009) Daniel C Baumgart et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
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- (2009) Ellen C Ebert et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Regulatory Lymphocytes and Intestinal Inflammation
- (2009) Ana Izcue et al. Annual Review of Immunology
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- (2009) Wendy S. Garrett et al. CANCER CELL
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- (2009) Banishree Saha et al. CYTOKINE
- S1066 Oral Alpha-4 Integrin Inhibitor (AJM300) in Patients with Active Crohn's Disease — A Randomized, Double-Blind, Placebo-Controlled Trial
- (2009) Masakazu Takazoe et al. GASTROENTEROLOGY
- Steroid-sparing properties of sargramostim in patients with corticosteroid-dependent Crohn's disease: a randomised, double-blind, placebo-controlled, phase 2 study
- (2009) J F Valentine et al. GUT
- Anti-CTLA-4 treatment induces IL-10-producing ICOS+ regulatory T cells displaying IDO-dependent anti-inflammatory properties in a mouse model of colitis
- (2009) C Coquerelle et al. GUT
- The interleukin-23 axis in intestinal inflammation
- (2009) Philip P. Ahern et al. IMMUNOLOGICAL REVIEWS
- Janus kinases in immune cell signaling
- (2009) Kamran Ghoreschi et al. IMMUNOLOGICAL REVIEWS
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- (2009) Walter Reinisch et al. INFLAMMATORY BOWEL DISEASES
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- (2009) Daniel C. Baumgart et al. INFLAMMATORY BOWEL DISEASES
- Granulocyte-macrophage colony-stimulating factor elicits bone marrow-derived cells that promote efficient colonic mucosal healing
- (2009) Eric Bernasconi et al. INFLAMMATORY BOWEL DISEASES
- Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease
- (2009) Andrew M. Smith et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Early-onset Crohn Disease Is Associated With Male Sex and a Polymorphism in the IL-6 Promoter
- (2009) Keren Sagiv-Friedgut et al. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION
- A protective function for interleukin 17A in T cell–mediated intestinal inflammation
- (2009) William O'Connor Jr et al. NATURE IMMUNOLOGY
- Inflammatory Bowel Disease
- (2009) Clara Abraham et al. NEW ENGLAND JOURNAL OF MEDICINE
- Clinical trial: a multicentre, randomized, double-blind, placebo-controlled, dose-finding, phase II study of subcutaneous interferon-β-1a in moderately active ulcerative colitis
- (2008) C. PENA-ROSSI et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Anti-adhesion molecule therapies in inflammatory bowel disease: Touch and go
- (2008) Tommaso Stefanelli et al. AUTOIMMUNITY REVIEWS
- The role of granulocyte macrophage-colony-stimulating factor in acute intestinal inflammation
- (2008) Yinghua Xu et al. CELL RESEARCH
- Treatment of Active Crohn's Disease With MLN0002, a Humanized Antibody to the α4β7 Integrin
- (2008) Brian G. Feagan et al. Clinical Gastroenterology and Hepatology
- Visilizumab induces apoptosis of mucosal T lymphocytes in ulcerative colitis through activation of caspase 3 and 8 dependent pathways
- (2008) Qi T. Yu et al. CLINICAL IMMUNOLOGY
- Mucosal T Cell Proliferation and Apoptosis in Inflammatory Bowel Disease
- (2008) Andreas Sturm et al. CURRENT DRUG TARGETS
- Clinical course of ulcerative colitis
- (2008) M. Cottone et al. DIGESTIVE AND LIVER DISEASE
- Role of β7 Integrin and the Chemokine/Chemokine Receptor Pair CCL25/CCR9 in Modeled TNF-Dependent Crohn's Disease
- (2008) Maria Apostolaki et al. GASTROENTEROLOGY
- A Randomized Trial of Ustekinumab, a Human Interleukin-12/23 Monoclonal Antibody, in Patients With Moderate-to-Severe Crohn's Disease
- (2008) William J. Sandborn et al. GASTROENTEROLOGY
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- (2008) Xiaonan Han et al. GASTROENTEROLOGY
- Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis
- (2008) Ana Izcue et al. IMMUNITY
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- (2008) Robert A. Edwards et al. INFLAMMATORY BOWEL DISEASES
- Alterations in myeloid dendritic cell innate immune responses in the Gαi2-deficient mouse model of colitis
- (2008) J. A. Peña et al. INFLAMMATORY BOWEL DISEASES
- Validation of murine dextran sulfate sodium-induced colitis using four therapeutic agents for human inflammatory bowel disease
- (2008) Silvia Melgar et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Regulation of inflammatory responses by IL-17F
- (2008) Xuexian O. Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
- (2008) Andre Franke et al. NATURE GENETICS
- Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
- (2008) Jeffrey C Barrett et al. NATURE GENETICS
- Efficient colonic mucosal wound repair requires Trem2 signaling
- (2008) H. Seno et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Antibiotic-Responsive Mouse Model of Fulminant Ulcerative Colitis
- (2008) Silvia S Kang et al. PLOS MEDICINE
- Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis
- (2007) Satheesh K. Sainathan et al. INFLAMMATORY BOWEL DISEASES
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