Pharmacological intervention studies using mouse models of the inflammatory bowel diseases

Pathogenic and Protective Roles of MyD88 in Leukocytes and Epithelial Cells in Mouse Models of Inflammatory Bowel Disease

(2010) Mark J. Asquith et al.   GASTROENTEROLOGY

Microbiota innate stimulation is a prerequisite for T cell spontaneous proliferation and induction of experimental colitis

(2010) Ting Feng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Publication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy

(2010) Emily S. Sena et al.   PLOS BIOLOGY

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Regulatory Lymphocytes and Intestinal Inflammation

(2009) Ana Izcue et al.   Annual Review of Immunology

Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases

(2009) Claudio Napoli et al.   ARCHIVES OF PHARMACAL RESEARCH

Mouse models of intestinal inflammation as tools to understand the pathogenesis of inflammatory bowel disease

(2009) Holm H. Uhlig et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TLR2-independent induction and regulation of chronic intestinal inflammation

(2009) Olivier Boulard et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T Cells Reinforce Intestinal Homeostasis

(2009) Michael J. Barnes et al.   IMMUNITY

Blocking CD27-CD70 Costimulatory Pathway Suppresses Experimental Colitis

(2009) M. Manocha et al.   JOURNAL OF IMMUNOLOGY

Usefulness of CD4+CD45RBhigh CD25− Cell–Transferred SCID Mice for Preclinical Evaluation of Drugs for Inflammatory Bowel Disease

(2009) Daisuke Hirano et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

T cell transfer model of chronic colitis: concepts, considerations, and tricks of the trade

(2008) Dmitry V. Ostanin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Raf Protects Against Colitis by Promoting Mouse Colon Epithelial Cell Survival Through NF-κB

(2008) Karen L. Edelblum et al.   GASTROENTEROLOGY

The ErbB4 Growth Factor Receptor Is Required for Colon Epithelial Cell Survival in the Presence of TNF

(2008) Mark R. Frey et al.   GASTROENTEROLOGY

Regulation of intestinal barrier function by signal transducer and activator of transcription 5b

(2008) X Han et al.   GUT

Efficient colonic mucosal wound repair requires Trem2 signaling

(2008) H. Seno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for the Efficacy of NXY-059 in Experimental Focal Cerebral Ischaemia Is Confounded by Study Quality

(2008) Malcolm R. Macleod et al.   STROKE

Empirical Evidence of Bias in the Design of Experimental Stroke Studies

(2008) Nicolas A. Crossley et al.   STROKE

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

(2007) Andreas Robinson et al.   GASTROENTEROLOGY