IL-1β and ADAM17 are central regulators of β-defensin expression in Candida esophagitis

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

(2010) Athena Chalaris et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

The expression of the beta-defensins hBD-2 and hBD-3 is differentially regulated by NF-kappaB and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis

(2009) Nadine Steubesand et al.   BMC IMMUNOLOGY

Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion

(2009) A. Brill et al.   CARDIOVASCULAR RESEARCH

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

ATP-mediated Activation of the NADPH Oxidase DUOX1 Mediates Airway Epithelial Responses to Bacterial Stimuli

(2009) Agnes W. Boots et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of the NLRP3 Inflammasome in Innate and Humoral Adaptive Immune Responses to Fungal  -Glucan

(2009) H. Kumar et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome

(2009) S. Joly et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial Reactive Oxygen Species Mediate GPCR–induced TACE/ADAM17-dependent Transforming Growth Factor-α Shedding

(2009) Timothy J. Myers et al.   MOLECULAR BIOLOGY OF THE CELL

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Multiple TLRs activate EGFR via a signaling cascade to produce innate immune responses in airway epithelium

(2008) Jonathan L. Koff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Activation of Toll-like receptors by Burkholderia pseudomallei

(2008) T Eoin West et al.   BMC IMMUNOLOGY

Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages

(2008) Gerben Ferwerda et al.   CELLULAR MICROBIOLOGY

Antimicrobial host defense in the upper gastrointestinal tract

(2008) Yoshio Hosaka et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases

(2008) P-R. Burgel et al.   EUROPEAN RESPIRATORY JOURNAL

Host defense mechanisms in invasive candidiasis originating in the GI tract

(2008) Manuel Vilanova et al.   Expert Review of Anti-Infective Therapy

Transcriptome Profile of the Vascular Endothelial Cell Response toCandida albicans

(2008) Katherine S. Barker et al.   JOURNAL OF INFECTIOUS DISEASES

Overexpression of human β-defensin-3 in oral dysplasia: Potential role in macrophage trafficking

(2008) Hameem I. Kawsar et al.   ORAL ONCOLOGY

IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis

(2007) Alexander Arlt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis

(2007) Mihai G. Netea et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY