Acquired cisplatin resistance in human ovarian A2780 cancer cells correlates with shift in taurine homeostasis and ability to volume regulate

mTOR ensures increased release and reduced uptake of the organic osmolyte taurine under hypoosmotic conditions in mouse fibroblasts

(2014) Ian Henry Lambert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

PTEN overexpression improves cisplatin-resistance of human ovarian cancer cells through upregulating KRT10 expression

(2014) Huijuan Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel

(2014) Zhaozhu Qiu et al.   CELL

Ion channels and transporters in the development of drug resistance in cancer cells

(2014) E. K. Hoffmann et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Identification of LRRC8 Heteromers as an Essential Component of the Volume-Regulated Anion Channel VRAC

(2014) F. K. Voss et al.   SCIENCE

Role of SLC6A6 in promoting the survival and multidrug resistance of colorectal cancer

(2014) Masahiro Yasunaga et al.   Scientific Reports

Organic Cation Transporter OCTs (SLC22) and MATEs (SLC47) in the Human Kidney

(2013) Hideyuki Motohashi et al.   AAPS Journal

Volume-sensitive release of organic osmolytes in the human lung epithelial cell line A549: role of the 5-lipoxygenase

(2013) Jacob Bak Holm et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

EDD enhances cell survival and cisplatin resistance and is a therapeutic target for epithelial ovarian cancer

(2013) Amber Bradley et al.   CARCINOGENESIS

LINGO-1 Receptor Promotes Neuronal Apoptosis by Inhibiting WNK3 Kinase Activity

(2013) Zhaohuan Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRRC8 proteins share a common ancestor with pannexins, and may form hexameric channels involved in cell-cell communication

(2012) Federico Abascal et al.   BIOESSAYS

DNA damage-induced cell death: From specific DNA lesions to the DNA damage response and apoptosis

(2012) Wynand P. Roos et al.   CANCER LETTERS

Downregulation of the Taurine Transporter TauT During Hypo-Osmotic Stress in NIH3T3 Mouse Fibroblasts

(2012) Daniel Bloch Hansen et al.   JOURNAL OF MEMBRANE BIOLOGY

Ion channnels and transporters in cancer. 5. Ion channels in control of cancer and cell apoptosis

(2011) V'yacheslav Lehen'kyi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Taurine protects rat testes against doxorubicin-induced oxidative stress as well as p53, Fas and caspase 12-mediated apoptosis

(2011) Joydeep Das et al.   AMINO ACIDS

Mechanism underlying the antioxidant activity of taurine: prevention of mitochondrial oxidant production

(2011) Chian Ju Jong et al.   AMINO ACIDS

Pinpointing Differences in Cisplatin-induced Apoptosis in Adherent and Non-adherent Cancer Cells

(2011) Hanne S. Tastesen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Regulation of Taurine Transport Systems by Protein Kinase CK2 in Mammalian Cells

(2011) Ian Henry Lambert et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Dysfunction of volume-sensitive chloride channels contributes to cisplatin resistance in human lung adenocarcinoma cells

(2011) Xian-jun Min et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation

(2011) Y. Qu et al.   JOURNAL OF IMMUNOLOGY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Human mitochondrial diseases caused by lack of taurine modification in mitochondrial tRNAs

(2011) Suzuki Tsutomu et al.   Wiley Interdisciplinary Reviews-RNA

Acute cholesterol depletion leads to net loss of the organic osmolyte taurine in Ehrlich Lettré tumor cells

(2010) Kasper Rømer Villumsen et al.   AMINO ACIDS

Regulation of taurine homeostasis by protein kinase CK2 in mouse fibroblasts

(2010) Daniel Bloch Hansen et al.   AMINO ACIDS

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Deregulation of apoptotic volume decrease and ionic movements in multidrug-resistant tumor cells: role of chloride channels

(2009) K. A. Poulsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Taurine protects transformed rat retinal ganglion cells from hypoxia-induced apoptosis by preventing mitochondrial dysfunction

(2009) Ka Chen et al.   BRAIN RESEARCH

Pharmacogenetics of Drug Transporters

(2009) R. Franke et al.   CURRENT PHARMACEUTICAL DESIGN

Aberration of the PI3K/AKT/mTOR signaling in epithelial ovarian cancer and its implication in cisplatin-based chemotherapy

(2009) Hai-Yan Zhang et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Functional TauT Protects Against Acute Kidney Injury

(2009) X. Han et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inhibition of transcription by platinum antitumor compounds

(2009) Ryan C. Todd et al.   Metallomics

Physiology of Cell Volume Regulation in Vertebrates

(2009) Else K. Hoffmann et al.   PHYSIOLOGICAL REVIEWS

Cell volume regulation: physiology and pathophysiology

(2008) I. H. Lambert et al.   Acta Physiologica

Casein kinase 2 regulates the active uptake of the organic osmolyte taurine in NIH3T3 mouse fibroblasts

(2008) Jack H. Jacobsen et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY