Role of the fourth transmembrane domain in proton-coupled folate transporter function as assessed by the substituted cysteine accessibility method

Identification of a functionally critical GXXG motif and its relationship to the folate binding site of the proton-coupled folate transporter (PCFT-SLC46A1)

(2012) Rongbao Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A P425R mutation of the proton-coupled folate transporter causing hereditary folate malabsorption produces a highly selective alteration in folate binding

(2012) Daniel Sanghoon Shin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Functional roles of the A335 and G338 residues of the proton-coupled folate transporter (PCFT-SLC46A1) mutated in hereditary folate malabsorption

(2012) Daniel Sanghoon Shin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Mechanisms of Membrane Transport of Folates into Cells and Across Epithelia

(2011) Rongbao Zhao et al.   Annual Review of Nutrition

Vulnerability of the cysteine-less proton-coupled folate transporter (PCFT-SLC46A1) to mutational stress associated with the substituted cysteine accessibility method

(2011) Rongbao Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Identification and Functional Impact of Homo-oligomers of the Human Proton-coupled Folate Transporter

(2011) Zhanjun Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Random Mutagenesis of the Proton-coupled Folate Transporter (SLC46A1), Clustering of Mutations, and the Bases for Associated Losses of Function

(2011) Rongbao Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter

(2011) S. Kugel Desmoulin et al.   MOLECULAR PHARMACOLOGY

Properties of the Arg376 residue of the proton-coupled folate transporter (PCFT-SLC46A1) and a glutamine mutant causing hereditary folate malabsorption

(2010) Kris Mahadeo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Membrane Topological Analysis of the Proton-Coupled Folate Transporter (PCFT-SLC46A1) by the Substituted Cysteine Accessibility Method

(2010) Rongbao Zhao et al.   BIOCHEMISTRY

Functional roles of aspartate residues of the proton-coupled folate transporter (PCFT-SLC46A1); a D156Y mutation causing hereditary folate malabsorption

(2010) D. S. Shin et al.   BLOOD

Transmembrane Segment 11 Appears to Line the Purine Permeation Pathway of thePlasmodium falciparumEquilibrative Nucleoside Transporter 1 (PfENT1)

(2010) Paul M. Riegelhaupt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors

(2010) S. K. Desmoulin et al.   MOLECULAR PHARMACOLOGY

Role of the glutamate 185 residue in proton translocation mediated by the proton-coupled folate transporter SLC46A1

(2009) Ersin Selcuk Unal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hereditary folate malabsorption: A positively charged amino acid at position 113 of the proton-coupled folate transporter (PCFT/SLC46A1) is required for folic acid binding

(2009) Inbal Lasry et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Functional Roles of the His247and His281Residues in Folate and Proton Translocation Mediated by the Human Proton-coupled Folate Transporter SLC46A1

(2009) Ersin Selcuk Unal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal trancriptional regulatory region in an antifolate-resistant HeLa cell line

(2009) N. K. Diop-Bove et al.   MOLECULAR CANCER THERAPEUTICS

Modelling and mutational evidence identify the substrate binding site and functional elements in APC amino acid transporters

(2009) Ioannis Vangelatos et al.   MOLECULAR MEMBRANE BIOLOGY

Alignment of multiple protein structures based on sequence and structure features

(2009) M.S. Madhusudhan et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for function

(2008) I. Lasry et al.   BLOOD

Mechanism for alternating access in neurotransmitter transporters

(2008) L. R. Forrest et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA