RNA Sequencing Analysis Detection of a Novel Pathway of Endothelial Dysfunction in Pulmonary Arterial Hypertension

Elafin Reverses Pulmonary Hypertension via Caveolin-1–Dependent Bone Morphogenetic Protein Signaling

(2015) Nils P. Nickel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Proteomic Analysis Implicates Translationally Controlled Tumor Protein as a Novel Mediator of Occlusive Vascular Remodeling in Pulmonary Arterial Hypertension

(2014) Jessie R. Lavoie et al.   CIRCULATION

The high mobility group A1 molecular switch: turning on cancer – can we turn it off?

(2014) Tait H Huso et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The MicroRNA-130/301 Family Controls Vasoconstriction in Pulmonary Hypertension

(2014) Thomas Bertero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF-1 Alpha-Induced Up-Regulation of miR-9 Contributes to Phenotypic Modulation in Pulmonary Artery Smooth Muscle Cells During Hypoxia

(2014) Fabo Shan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension

(2014) Hirofumi Sawada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Basal PIR expression in HeLa cells is driven by NRF2 via evolutionary conserved antioxidant response element

(2014) Kamil Brzóska et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Nitrosation-Dependent Caveolin 1 Phosphorylation, Ubiquitination, and Degradation and its Association with Idiopathic Pulmonary Arterial Hypertension

(2014) Farnaz R. Bakhshi et al.   Pulmonary Circulation

Endothelial Expression of Guidance Cues in Vessel Wall Homeostasis Dysregulation Under Proatherosclerotic Conditions

(2013) Janine M. van Gils et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

DNAJB4 molecular chaperone distinguishes WT from mutant E-cadherin, determining their fate in vitro and in vivo

(2013) Joana Simões-Correia et al.   HUMAN MOLECULAR GENETICS

An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation

(2013) Daniel M. Hohenhaus et al.   IMMUNOBIOLOGY

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension

(2013) Edda Spiekerkoetter et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-21 Integrates Pathogenic Signaling to Control Pulmonary Hypertension

(2012) Victoria N. Parikh et al.   CIRCULATION

Pulmonary Arterial Hypertension in Patients Treated by Dasatinib

(2012) David Montani et al.   CIRCULATION

Loss of Adenomatous Poliposis Coli-α3 Integrin Interaction Promotes Endothelial Apoptosis in Mice and Humans

(2012) Vinicio A. de Jesus Perez et al.   CIRCULATION RESEARCH

Molecular pathogenesis of pulmonary arterial hypertension

(2012) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

Erythroid-Specific Transcriptional Changes in PBMCs from Pulmonary Hypertension Patients

(2012) Chris Cheadle et al.   PLoS One

Metabolomic Analysis of Bone Morphogenetic Protein Receptor Type 2 Mutations in Human Pulmonary Endothelium Reveals Widespread Metabolic Reprogramming

(2012) Joshua P. Fessel et al.   Pulmonary Circulation

Biomimetic Hydrogels with Immobilized EphrinA1 for Therapeutic Angiogenesis

(2011) Jennifer E. Saik et al.   BIOMACROMOLECULES

Epidermal Growth Factor Receptor (EGFR)-mediated Positive Feedback of Protein-tyrosine Phosphatase ϵ (PTPϵ) on ERK1/2 and AKT Protein Pathways Is Required for Survival of Human Breast Cancer Cells

(2011) Caroline E. Nunes-Xavier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Down-regulation of Krüppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-β and Bone Morphogenetic Protein 4

(2011) Brandi N. Davis-Dusenbery et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

(2011) Tero-Pekka Alastalo et al.   JOURNAL OF CLINICAL INVESTIGATION

Somatic Chromosome Abnormalities in the Lungs of Patients with Pulmonary Arterial Hypertension

(2010) Micheala A. Aldred et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Activation of NAD(P)H Oxidases by Thromboxane A 2 Receptor Uncouples Endothelial Nitric Oxide Synthase

(2010) Miao Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension

(2010) Eileen Hsu et al.   ARTHRITIS AND RHEUMATISM

Bone morphogenetic protein receptor II regulates pulmonary artery endothelial cell barrier function

(2010) V. J. Burton et al.   BLOOD

Regulation of heart valve morphogenesis by Eph receptor ligand, ephrin-A1

(2010) Leslie A. Frieden et al.   DEVELOPMENTAL DYNAMICS

High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells

(2010) Bin Du et al.   FEBS LETTERS

H5N1 Virus Activates Signaling Pathways in Human Endothelial Cells Resulting in a Specific Imbalanced Inflammatory Response

(2010) D. Viemann et al.   JOURNAL OF IMMUNOLOGY

Dasatinib reduces FAK phosphorylation increasing the effects of RPI-1 inhibition in a RET/PTC1-expressing cell line

(2010) Dario Caccia et al.   Molecular Cancer

Human C-reactive protein induces endothelial dysfunction and uncoupling of eNOS in vivo

(2009) Travis W. Hein et al.   ATHEROSCLEROSIS

Bone Morphogenetic Protein (BMP) and Activin Type II Receptors Balance BMP9 Signals Mediated by Activin Receptor-like Kinase-1 in Human Pulmonary Artery Endothelial Cells

(2009) Paul D. Upton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt–β-catenin and Wnt–RhoA–Rac1 pathways

(2009) Vinicio A. de Jesus Perez et al.   JOURNAL OF CELL BIOLOGY

Identification of Interferon-β-Stimulated Genes that Inhibit Angiogenesis In Vitro

(2008) Kevin L. Taylor et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Implications of Mutations of Activin Receptor-Like Kinase 1 Gene (ALK1) in Addition to Bone Morphogenetic Protein Receptor II Gene (BMPR2) in Children With Pulmonary Arterial Hypertension

(2007) Maya Fujiwara et al.   CIRCULATION JOURNAL