Basal PIR expression in HeLa cells is driven by NRF2 via evolutionary conserved antioxidant response element

Pirin is an iron-dependent redox regulator of NF- B

(2013) F. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK

(2012) Yu-yi Lin et al.   NATURE

Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha

(2012) B. N. Chorley et al.   NUCLEIC ACIDS RESEARCH

Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway

(2011) Miao Yu et al.   CELLULAR SIGNALLING

Molecular cross-talk between the NRF2/KEAP1 signaling pathway, autophagy, and apoptosis

(2011) Tomasz M. Stępkowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heme oxygenase 1 is induced by miR-155 via reduced BACH1 translation in endothelial cells

(2011) Kati H. Pulkkinen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Putative proto-oncogenePirexpression is significantly up-regulated in the spleen and kidney of cytosolic superoxide dismutase-deficient mice

(2011) Kamil Brzóska et al.   REDOX REPORT

When NRF2 Talks, Who's Listening?

(2010) Nobunao Wakabayashi et al.   ANTIOXIDANTS & REDOX SIGNALING

Pirin delocalization in melanoma progression identified by high content immuno-detection based approaches

(2010) Silvia Licciulli et al.   BMC CELL BIOLOGY

Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation

(2010) Barry R. Imhoff et al.   CELL BIOLOGY AND TOXICOLOGY

A small-molecule inhibitor shows that pirin regulates migration of melanoma cells

(2010) Isao Miyazaki et al.   Nature Chemical Biology

Pirin downregulation is a feature of AML and leads to impairment of terminal myeloid differentiation

(2009) S Licciulli et al.   LEUKEMIA

Unknown

(2009) Ralf-Harto Hubner et al.   MOLECULAR MEDICINE

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

(2009) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2–Keap1 signaling

(2008) Narayanan Sriram et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS