The MicroRNA-130/301 Family Controls Vasoconstriction in Pulmonary Hypertension

Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

(2014) Thomas Bertero et al.   JOURNAL OF CLINICAL INVESTIGATION

An expression atlas of human primary cells: inference of gene function from coexpression networks

(2013) Neil A Mabbott et al.   BMC GENOMICS

Circulating miRNAs as Potential Marker for Pulmonary Hypertension

(2013) Chuanyu Wei et al.   PLoS One

Hypoxia Mediates Mutual Repression between microRNA-27a and PPARγ in the Pulmonary Vasculature

(2013) Bum-Yong Kang et al.   PLoS One

Nitric oxide plays a minimal role in hypoxic pulmonary vasoconstriction in isolated rat lungs

(2013) T.S. Hakim et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

miR-210 has an antiapoptotic effect in pulmonary artery smooth muscle cells during hypoxia

(2012) Deming Gou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MicroRNA-21 Integrates Pathogenic Signaling to Control Pulmonary Hypertension

(2012) Victoria N. Parikh et al.   CIRCULATION

Endothelin Axis Is Upregulated in Human and Rat Right Ventricular Hypertrophy

(2012) Jayan Nagendran et al.   CIRCULATION RESEARCH

Peroxisome Proliferator-Activated Receptor-γ Ameliorates Pulmonary Arterial Hypertension by Inhibiting 5-Hydroxytryptamine 2B Receptor

(2012) Yahan Liu et al.   HYPERTENSION

Hypoxic pulmonary vasoconstriction requires connexin 40–mediated endothelial signal conduction

(2012) Liming Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular pathogenesis of pulmonary arterial hypertension

(2012) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

Downregulation of microRNA-126 in endothelial progenitor cells from diabetes patients, impairs their functional properties, via target gene Spred-1

(2012) S. Meng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

(2012) Jongmin Kim et al.   NATURE MEDICINE

Hypoxic Pulmonary Vasoconstriction

(2012) J. T. Sylvester et al.   PHYSIOLOGICAL REVIEWS

MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension

(2011) W.-H. Wu et al.   AMERICAN JOURNAL OF HYPERTENSION

The PPARγ ligand rosiglitazone attenuates hypoxia-induced endothelin signaling in vitro and in vivo

(2011) Bum-Yong Kang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A Novel Murine Model of Severe Pulmonary Arterial Hypertension

(2011) Loredana Ciuclan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

ROCK and JAK1 Signaling Cooperate to Control Actomyosin Contractility in Tumor Cells and Stroma

(2011) Victoria Sanz-Moreno et al.   CANCER CELL

Signal Transducers and Activators of Transcription-3/Pim1 Axis Plays a Critical Role in the Pathogenesis of Human Pulmonary Arterial Hypertension

(2011) Roxane Paulin et al.   CIRCULATION

Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

(2011) Tero-Pekka Alastalo et al.   JOURNAL OF CLINICAL INVESTIGATION

Role for miR-204 in human pulmonary arterial hypertension

(2011) Audrey Courboulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dynamic regulation of circulating microRNA during acute exhaustive exercise and sustained aerobic exercise training

(2011) Aaron L. Baggish et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mechanisms of disease: pulmonary arterial hypertension

(2011) Ralph T. Schermuly et al.   Nature Reviews Cardiology

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization

(2009) C. Guignabert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

MicroRNA-210 Controls Mitochondrial Metabolism during Hypoxia by Repressing the Iron-Sulfur Cluster Assembly Proteins ISCU1/2

(2009) Stephen Y. Chan et al.   Cell Metabolism

KEGG for representation and analysis of molecular networks involving diseases and drugs

(2009) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

PPAR  Activation: A Potential Treatment For Pulmonary Hypertension

(2009) G. Hansmann et al.   Science Translational Medicine

Interaction between bone morphogenetic proteins and endothelin-1 in human pulmonary artery smooth muscle

(2009) Sarah Din et al.   VASCULAR PHARMACOLOGY

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

(2009) Chunlei Wu et al.   GENOME BIOLOGY

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Molecular pathogenesis of pulmonary arterial hypertension

(2008) Marlene Rabinovitch   JOURNAL OF CLINICAL INVESTIGATION

An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension

(2008) Georg Hansmann et al.   JOURNAL OF CLINICAL INVESTIGATION

PID: the Pathway Interaction Database

(2008) Carl F. Schaefer et al.   NUCLEIC ACIDS RESEARCH

Reactome knowledgebase of human biological pathways and processes

(2008) L. Matthews et al.   NUCLEIC ACIDS RESEARCH

Endothelial cell dysfunction and cross talk between endothelium and smooth muscle cells in pulmonary arterial hypertension

(2008) Marc Humbert et al.   VASCULAR PHARMACOLOGY