Induction of autophagy by Imatinib sequesters Bcr-Abl in autophagosomes and down-regulates Bcr-Abl protein
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Induction of autophagy by Imatinib sequesters Bcr-Abl in autophagosomes and down-regulates Bcr-Abl protein
Authors
Keywords
-
Journal
AMERICAN JOURNAL OF HEMATOLOGY
Volume 88, Issue 6, Pages 455-462
Publisher
Wiley
Online
2013-02-26
DOI
10.1002/ajh.23428
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide
- (2012) D. J. Goussetis et al. BLOOD
- Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein
- (2011) Zhuo Wang et al. Autophagy
- Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling
- (2011) Emma Sandilands et al. NATURE CELL BIOLOGY
- Control of autophagy as a therapy for neurodegenerative disease
- (2011) Harry Harris et al. Nature Reviews Neurology
- Autophagy induction by Bcr-Abl-expressing cells facilitates their recovery from a targeted or nontargeted treatment
- (2010) Lisa C. Crowley et al. AMERICAN JOURNAL OF HEMATOLOGY
- Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein
- (2010) P. Isakson et al. BLOOD
- Bag1 directly routes immature BCR-ABL for proteasomal degradation
- (2010) F. Tsukahara et al. BLOOD
- The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy
- (2010) Maria Filimonenko et al. MOLECULAR CELL
- Cytoprotective effect of imatinib mesylate in non-BCR-ABL-expressing cells along with autophagosome formation
- (2009) Tadashi Ohtomo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Autophagy: links with the proteasome
- (2009) Trond Lamark et al. CURRENT OPINION IN CELL BIOLOGY
- Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells
- (2009) Cristian Bellodi et al. JOURNAL OF CLINICAL INVESTIGATION
- Cathepsin B release after imatinib-mediated lysosomal membrane permeabilization triggers BCR–ABL cleavage and elimination of chronic myelogenous leukemia cells
- (2009) A Puissant et al. LEUKEMIA
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- Monitoring treatment of chronic myeloid leukemia
- (2008) M. Baccarani et al. HAEMATOLOGICA
- Disruption of the Bcr-Abl/Hsp90 protein complex: a possible mechanism to inhibit Bcr-Abl-positive human leukemic blasts by novobiocin
- (2008) L X Wu et al. LEUKEMIA
- Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival
- (2007) Christopher Fung et al. MOLECULAR BIOLOGY OF THE CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation