Autophagy contributes to therapy-induced degradation of the PML/RARA oncoprotein

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

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Guidelines for the use and interpretation of assays for monitoring autophagy

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NBR1 and p62 as cargo receptors for selective autophagy of ubiquitinated targets

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Nutrient-dependent regulation of autophagy through the target of rapamycin pathway: Figure 1

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Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy

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Therapy-induced PML/RARA Proteolysis and Acute Promyelocytic Leukemia Cure

(2009) R. Nasr et al.   CLINICAL CANCER RESEARCH

Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-transretinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells

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ULK1·ATG13·FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

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Cell-cycle regulation and dynamics of cytoplasmic compartments containing the promyelocytic leukemia protein and nucleoporins

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Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation

(2009) Yu-Yun Chang et al.   MOLECULAR BIOLOGY OF THE CELL

Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia

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Autophagy in the Pathogenesis of Disease

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RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

(2008) Rihab Nasr et al.   NATURE MEDICINE