Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts

TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO

(2012) Stacey Robida-Stubbs et al.   Cell Metabolism

Mitochondrial SKN-1/Nrf Mediates a Conserved Starvation Response

(2012) Jennifer Paek et al.   Cell Metabolism

Assurance of mitochondrial integrity and mammalian longevity by the p62–Keap1–Nrf2–Nqo1 cascade

(2012) Jeongho Kwon et al.   EMBO REPORTS

Enteric-delivered rapamycin enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence

(2012) Cecilia A. Hinojosa et al.   EXPERIMENTAL GERONTOLOGY

Axis of ageing: telomeres, p53 and mitochondria

(2012) Ergün Sahin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype

(2011) Adam Freund et al.   EMBO JOURNAL

p62 Is a Key Regulator of Nutrient Sensing in the mTORC1 Pathway

(2011) Angeles Duran et al.   MOLECULAR CELL

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Autophagy Impairment Induces Premature Senescence in Primary Human Fibroblasts

(2011) Hyun Tae Kang et al.   PLoS One

Elimination of Proliferating Cells Unmasks the Shift from Senescence to Quiescence Caused by Rapamycin

(2011) Olga V. Leontieva et al.   PLoS One

Pleiotropic effects of growth hormone signaling in aging

(2011) Andrzej Bartke   TRENDS IN ENDOCRINOLOGY AND METABOLISM

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Long-Term IGF-I Exposure Decreases Autophagy and Cell Viability

(2010) Alessandro Bitto et al.   PLoS One

Transcriptional Control of Mitochondrial Biogenesis and Function

(2009) M. Benjamin Hock et al.   Annual Review of Physiology

Mitochondrial targeting of the electrophilic lipid 15-deoxy-Δ12,14prostaglandin J2increases apoptotic efficacy via redox cell signalling mechanisms

(2009) Anne R. Diers et al.   BIOCHEMICAL JOURNAL

p62 at the Crossroads of Autophagy, Apoptosis, and Cancer

(2009) Jorge Moscat et al.   CELL

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view

(2008) Gilad Twig et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

(2008) Jennifer M.A. Tullet et al.   CELL

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

(2008) Gilad Twig et al.   EMBO JOURNAL

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

Proteasome modulates mitochondrial function during cellular senescence

(2007) Claudio A. Torres et al.   FREE RADICAL BIOLOGY AND MEDICINE