Article
Clinical Neurology
Larissa Salvador, Luana Giatti, Maria Carmen Viana, Claudia Kimie Suemoto, Bruce B. Duncan, Maria del Carmen Bisi Molina, Maria de Jesus Mendes da Fonseca, Andre R. Brunoni, Sandhi Maria Barreto, Paulo Caramelli
Summary: This study aimed to investigate the impact of alcohol intake on cognition in middle-aged participants and found that heavy alcohol consumption can affect executive functions in men and memory in women, while moderate alcohol intake may have a protective effect on gender-specific cognitive functions.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Nutrition & Dietetics
Katherine Kent, Maziar Yousefi, Vinicius A. do Rosario, Zoe Fitzgerald, Samantha Broyd, Denis Visentin, Steven Roodenrys, Karen Walton, Karen E. Charlton
Summary: Research suggests that dietary anthocyanins may play a role in preventing cognitive decline in older adults. This study examined the association between usual anthocyanin intake and memory and cognition in older adults with mild cognitive impairment. The results showed that higher anthocyanin intake was linked to better cognitive performance.
NUTRITION RESEARCH
(2022)
Article
Geriatrics & Gerontology
Raquel Jimenez Gomez, Eduardo Jose Fernandez Rodriguez, Celia Sanchez Gomez, Juan Jesus Cruz Hernandez, Maria Isabel Rihuete Galve
Summary: The aim of this study was to translate the Everyday Cognition Battery (ECB) into Spanish, adapt it to the sociocultural context of Spain, and validate it by testing the psychometric properties. Results showed that the Spanish version of the ECB tool is socially and culturally equivalent to the original version, and both its validity and reliability for assessing everyday cognition in older adults have been demonstrated.
Review
Geriatrics & Gerontology
Yongfeng Lao, Lijuan Hou, Jing Li, Xu Hui, Peijing Yan, Kehu Yang
Summary: This study found a nonlinear dose-response relationship between alcohol intake and the risk of progression from MCI to dementia. Excessive alcohol intake was associated with an increased risk of progression from MCI to dementia.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
History & Philosophy Of Science
Duncan Pritchard, Andrea R. English, John Ravenscroft
Summary: The research focuses on whether the use of assistive technology in special needs education can be considered a form of extended cognition, suggesting that the relationship between students and AT is more than just instrumental. It is argued that special needs education provides a particularly plausible case for extended cognition, with important philosophical and practical implications for mainstream education in technologically-rich environments.
Article
Geriatrics & Gerontology
Ragnhild Munthe-Kaas, Stina Aam, Ingvild Saltvedt, Torgeir Bruun Wyller, Sarah T. Pendlebury, Stian Lydersen, Guri Hagberg, Till Schellhorn, Siri Rostoft, Hege Ihle-Hansen
Summary: This study compared the predictive value of pre-stroke Frailty Index (FI) and modified Rankin Scale (mRS) for post-stroke neurocognitive disorder (NCD). The results showed that FI was a stronger predictor of post-stroke NCD than mRS and could be included in the prediction models for cognitive prognosis post-stroke.
Article
Neurosciences
Lihuan Lan, Hongxuan Wang, Xiaoni Zhang, Qingyu Shen, Xiangpen Li, Lei He, Xiaoming Rong, Jialing Peng, Jingjing Mo, Ying Peng
Summary: Long-term alcohol intake leads to synapse loss and cognitive impairment. Microglia-mediated synaptic elimination may play a key role in this mechanism.
EXPERIMENTAL NEUROLOGY
(2022)
Article
Geriatrics & Gerontology
Varshini Varadaraj, Beatriz Munoz, Eleanor M. Simonsick, Bonnielin K. Swenor
Summary: The study found that visually impaired older adults participate in fewer cognitive activities. Compared to the unimpaired, groups with impairments in vision and contrast sensitivity had higher rates of decline in cognitive activities.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Review
Oncology
Samantha J. Mayo, Maryam Lustberg, Haryana M. Dhillon, Zev M. Nakamura, Deborah H. Allen, Diane Von Ah, Michelle C. Janelsins, Alexandre Chan, Karin Olson, Chia Jie Tan, Yi Long Toh, Jeong Oh, Lisa Grech, Yin Ting Cheung, Ishwaria Mohan Subbiah, Duska Petranovic, James D'Olimpio, Margherita Gobbo, Susanne Koeppen, Charles L. Loprinzi, Linda Pang, Shivani Shinde, Olanipekun Ntukidem, Katherine B. Peters
Summary: Cancer-related cognitive impairment (CRCI) is commonly experienced by individuals with non-central nervous system cancers, impacting the functional ability and quality of life of patients and their families. Oncology providers must know how to identify, assess, and educate patients and caregivers to mitigate this impact. This review aims to provide oncology clinicians with an overview of CRCI in adults with non-central nervous system cancers and current approaches in its identification, assessment, and management.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Clinical Neurology
Sheridan D. Chappelle, Christina Gigliotti, Gabriel C. Leger, Guerry M. Peavy, Diane M. Jacobs, Sarah J. Banks, Emily A. Little, Douglas Galasko, David P. Salmon
Summary: Remote screening for cognitive impairment associated with Alzheimer's disease is important due to the aging population and possible treatment options. In this study, the Telephone Interview for Cognitive Status (TICS) and the telephone adaptation of the Montreal Cognitive Assessment (T-MoCA) were effective in detecting cognitive impairment remotely, and both tests correlated with AD biomarkers.
ALZHEIMERS & DEMENTIA
(2023)
Article
Geriatrics & Gerontology
Yi Zhu, Yaxin Gao, Chuan Guo, Ming Qi, Ming Xiao, Han Wu, Jinhui Ma, Qian Zhong, Hongyuan Ding, Qiumin Zhou, Nawab Ali, Li Zhou, Qin Zhang, Ting Wu, Wei Wang, Cuiyun Sun, Lehana Thabane, Ling Zhang, Tong Wang
Summary: This study demonstrates that aerobic dance can increase the right and total hippocampal volumes and improve episodic memory in elderly individuals with amnestic mild cognitive impairment (aMCI).
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Review
Geriatrics & Gerontology
Elena S. George, Surbhi Sood, Robin M. Daly, Sze-Yen Tan
Summary: The review explores the association between NAFLD and cognitive function. The results from 11 observational studies suggest that NAFLD is associated with lower cognitive performance across several domains.
Article
Neurosciences
Tomohiko Sato, Haruo Hanyu, Yumi Koyama, Haruka Horita, Toshinori Aoki, Kentaro Hirao, Hidekazu Kanetaka, Soichiro Shimizu
Summary: The discrepancy between cognitive and imaging findings in AD patients is associated with cognitive reserve, measured by a combination of leisure activity and education levels, indicating that lifestyle interventions may be able to delay clinical symptoms of AD.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Review
Medicine, General & Internal
Aravind Ganesh, Philip A. Barber
Summary: There is evidence suggesting that TIA has cognitive consequences beyond the risk of recurrent stroke. TIA can provide insights into early mixed vascular-neurodegenerative cognitive decline and serve as a warning event for stroke and dementia prevention. This review discusses the challenges in studying TIA-related cognitive impairment and provides an overview of transient and long-term cognitive impairment after TIA.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Neurosciences
Ahmad Alhowail
Summary: Alcohol is commonly used by pregnant women as an illicit substance, but it can have long-lasting effects on cognitive functions of the offspring by affecting fetal brain development. The mechanisms altered following prenatal alcohol exposure include long-term potentiation, mitochondrial function, and protein kinase activation, and these changes are potentially associated with behavioral changes in affected offspring.
Article
Clinical Neurology
Ilona Merikanto, Yves Dauvilliers, Frances Chung, Yun Kwok Wing, Luigi De Gennaro, Brigitte Holzinger, Bjorn Bjorvatn, Charles M. Morin, Thomas Penzel, Christian Benedict, Adrijana Koscec Bjelajac, Ngan Yin Chan, Colin A. Espie, Harald Hrubos-Strom, Yuichi Inoue, Maria Korman, Anne-Marie Landtblom, Damien Leger, Kentaro Matsui, Sergio Mota-Rolim, Michael R. Nadorff, Giuseppe Plazzi, Catia Reis, Juliana Yordanova, Markku Partinen
Summary: An international survey study reveals that post-acute sequelae of COVID-19 symptoms are more prevalent among severe cases and long-lasting sleep problems are at the core of these symptoms. Understanding the importance of sleep-related symptoms has clinical relevance in diagnosing and treating long-COVID.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Elisa M. S. Meth, Luiz Eduardo Mateus Brandao, Lieve T. van Egmond, Pei Xue, Anastasia Grip, Jiafei Wu, Ayaat Adan, Filip Andersson, Andre P. Pacheco, Kerstin Uvnas-Moberg, Jonathan Cedernaes, Christian Benedict
Summary: Using a weighted blanket may result in a significant increase in melatonin release before sleep, potentially providing therapeutic benefits for insomnia and anxiety.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Biology
Bjorn Bjorvatn, Ilona Merikanto, Catia Reis, Maria Korman, Adrijana Koscec Bjelajac, Brigitte Holzinger, Luigi De Gennaro, Yun Kwok Wing, Charles M. Morin, Colin A. Espie, Christian Benedict, Anne-Marie Landtblom, Kentaro Matsui, Harald Hrubos-Strom, Sergio Mota-Rolim, Michael R. Nadorff, Giuseppe Plazzi, Rachel Ngan Yin Chan, Markku Partinen, Yves Dauvilliers, Frances Chung, Ingeborg Forthun
Summary: The present study aimed to investigate the relationship between shift/night work and face-to-face work with the prevalence and severity of COVID-19. The results showed that shift/night work was not associated with an increased risk of COVID-19, but shift/night workers reported more severe disease when infected. Face-to-face work was associated with an increased risk of COVID-19, but not with higher disease severity.
CHRONOBIOLOGY INTERNATIONAL
(2023)
Article
Endocrinology & Metabolism
Yan Zhao, Yuchan Zheng, Yixin Tian, Qian Yu, Lijun Qin, Kai Xu, Biao Sun, Christian Benedict, Baoyi Chen, Lijun Wei, Xiao Tan
Summary: The aim of this study was to investigate the association between objective sleep parameters and glycaemic variability in patients with type 2 diabetes. The results showed that sleep duration, sleep midpoint, and their daily variability were associated with glucose control in these patients.
DIABETES OBESITY & METABOLISM
(2023)
Review
Peripheral Vascular Disease
Michelle L. Gumz, Daichi Shimbo, Marwah Abdalla, Ravi C. Balijepalli, Christian Benedict, Yabing Chen, David J. Earnest, Karen L. Gamble, Scott R. Garrison, Ming C. Gong, John B. Hogenesch, Yuling Hong, Jessica R. Ivy, Bina Joe, Aaron D. Laposky, Mingyu Liang, Eric J. MacLaughlin, Tami A. Martino, David M. Pollock, Susan Redline, Amy Rogers, R. Dan Rudic, Eva S. Schernhammer, George S. Stergiou, Marie-Pierre St-Onge, Xiaoling Wang, Jacqueline Wright, Young S. Oh
Summary: Healthy individuals experience variation in blood pressure over a 24-hour period, with higher levels during wakefulness and lower levels during sleep. Disruption of the blood pressure circadian rhythm has been associated with negative health outcomes such as cardiovascular disease, dementia, and chronic kidney disease. Current approaches to diagnosis and treatment do not adequately consider the circadian rhythmicity of blood pressure. This review summarizes findings from a workshop held by the National Heart, Lung, and Blood Institute to identify knowledge gaps and research opportunities related to the study of blood pressure circadian rhythm and chronotherapy for hypertension.
Article
Endocrinology & Metabolism
Lieve T. van Egmond, Elisa M. S. Meth, Joachim Engstrom, Maria Ilemosoglou, Jasmin Annica Keller, Heike Vogel, Christian Benedict
Summary: This study investigates the effects of acute total sleep deprivation on blood concentrations of leptin, ghrelin, and adiponectin. The results show that sleep deprivation reduces levels of leptin while increasing levels of ghrelin and adiponectin. These changes are more pronounced in women and among individuals with obesity.
Article
Psychiatry
Pei Xue, Ilona Merikanto, Frances Chung, Charles M. Morin, Colin Espie, Bjorn Bjorvatn, Jonathan Cedernaes, Anne-Marie Landtblom, Thomas Penzel, Luigi De Gennaro, Brigitte Holzinger, Kentaro Matsui, Harald Hrubos-Strom, Maria Korman, Damien Leger, Sergio Mota-Rolim, Courtney J. Bolstad, Michael Nadorff, Giuseppe Plazzi, Catia Reis, Rachel Ngan Yin Chan, Yun Kwok Wing, Juliana Yordanova, Adrijana Koscec Bjelajac, Yuichi Inoue, Markku Partinen, Yves Dauvilliers, Christian Benedict
Summary: Short and long sleep duration after receiving mRNA vaccines is associated with a higher risk of post-COVID symptoms. The study suggests that short and long sleepers are more likely to experience prolonged COVID-19 symptoms compared to normal sleepers. Further research is needed to validate these findings in cohorts with confirmed SARS-CoV-2 infection.
TRANSLATIONAL PSYCHIATRY
(2023)
Article
Critical Care Medicine
Gabriel Baldanzi, Sergi Sayols-Baixeras, Jenny Theorell-Haglow, Koen F. Dekkers, Ulf Hammar, Diem Nguyen, Yi-Ting Lin, Shafqat Ahmad, Jacob Bak Holm, Henrik Bjorn Nielsen, Louise Brunkwall, Christian Benedict, Jonathan Cedernaes, Sanna Koskiniemi, Mia Phillipson, Lars Lind, Johan Sundstrom, Goran Bergstrom, Gunnar Engstrom, J. Gustav Smith, Marju Orho-Melander, Johan Arnlov, Beatrice Kennedy, Eva Lindberg, Tove Fall
Summary: This study explores the relationship between obstructive sleep apnea (OSA) and the composition and potential functions of the human gut microbiota. The results show that OSA-related hypoxia is associated with specific gut microbiota species and functions, and can lead to a decrease in microbial diversity. These findings provide a foundation for future research on the health effects of OSA on the gut microbiota.
Article
Endocrinology & Metabolism
Pei Xue, Xiao Tan, Christian Benedict
Summary: This study investigated the association between socioeconomic deprivation and sleep health indicators in patients with type 2 diabetes mellitus, as well as whether socioeconomic deprivation is associated with higher HbA1c levels in these patients. The results showed that socioeconomic deprivation is associated with poor sleep health and inadequate blood sugar control.
DIABETES OBESITY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Lulu Yang, Hongliang Feng, Jie Chen, Yun Kwok Wing, Christian Benedict, Xiao Tan, Jihui Zhang
Summary: This study found that disrupted circadian rest-activity rhythm (CRAR) is associated with cardiovascular diseases and mortality among people with type 2 diabetes. Specifically, individuals with low interdaily stability (IS) and relative amplitude (RA) had the highest risk of developing cardiovascular disease. Delayed L5 onset did not have a significant association with cardiovascular disease risk. Moreover, high intradaily variability (IV) and low RA were associated with all-cause and cardiovascular mortality.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Editorial Material
Endocrinology & Metabolism
Pei Xue, Diana A. Noga, Christian Benedict
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Clinical Neurology
Pei Xue, Xiao Tan, Christian Benedict
Summary: The American Diabetes Association recommends a target of less than 7% for treating type 2 diabetes mellitus. It is uncertain if poor sleep affects this goal. A study using data from 5703 patients on metformin monotherapy found that a higher poor sleep score, including elements such as snoring, was associated with a glycated haemoglobin of >= 7%. However, adjusting for health and lifestyle factors eliminated the significant associations.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
David Ojalvo, Andre Pekkola Pacheco, Christian Benedict
Summary: Using sleep wearables does not worsen sleep worries among patients with insomnia. In a 4-week study, patients wore the Fitbit Inspire 2 sleep tracker and improved their sleep diary with a self-help guide. Results showed significant improvements in sleep quality, stress reactivity, and quality of life for all patients. However, there were no significant differences between the Fitbit and control groups in terms of sleep duration and efficiency.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Multidisciplinary Sciences
Hongliang Feng, Lulu Yang, Yannis Yan Liang, Sizhi Ai, Yaping Liu, Yue Liu, Xinyi Jin, Binbin Lei, Jing Wang, Nana Zheng, Xinru Chen, Joey W. Y. Chan, Raymond Kim Wai Sum, Ngan Yin Chan, Xiao Tan, Christian Benedict, Yun Kwok Wing, Jihui Zhang
Summary: There is increasing interest in the role of timing of physical activity (PA) in improving health. A large-scale study shows that engaging in moderate-to-vigorous PA at the optimal time of day can significantly reduce mortality risk and maximize the benefits of PA.
NATURE COMMUNICATIONS
(2023)
Article
Health Care Sciences & Services
Lulu Yang, Hongliang Feng, Sizhi Ai, Yue Liu, Binbin Lei, Jie Chen, Xiao Tan, Christian Benedict, Ningjian Wang, Yun Kwok Wing, Lu Qi, Jihui Zhang
Summary: Evidence suggests a potential relationship between circadian rhythm and atrial fibrillation (AF), however, it is largely unknown whether circadian disruption can predict the onset of AF in the general population. This study aimed to investigate the association between accelerometer-measured circadian rest-activity rhythm (CRAR) and the risk of AF, as well as examine the joint associations and potential interactions of CRAR and genetic susceptibility with AF incidence. The results indicate that low amplitude, delayed acrophase, and low mesor are significantly associated with a higher risk of AF.
NPJ DIGITAL MEDICINE
(2023)