Construction of Vicinal Tetrasubstituted Stereogenic Centers via a Mannich-Type Organocatalyzed Addition of Δ2 -Pyrrolin-4-ones to Isatin Imines

Asymmetric synthesis of trifluoromethyl-substituted 3,3′-pyrrolidinyl-dispirooxindoles through organocatalytic 1,3-dipolar cycloaddition reactions

(2017) Wei-Jie Huang et al.   Organic Chemistry Frontiers

1,3-Diamine-Derived Bifunctional Organocatalyst Prepared from Camphor

(2016) Sebastijan Ričko et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Enantioselective Alkylation of Pyrazol-3-ones with Isatin-Derived Ketimines: Stereocontrolled Construction of Vicinal Tetrasubstituted Stereocenters

(2016) Fares Ibrahim Amr et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic asymmetric Henry reaction of 1H-pyrrole-2,3-diones with bifunctional amine-thiourea catalysts bearing multiple hydrogen-bond donors

(2016) Ming-Liang Zhang et al.   Beilstein Journal of Organic Chemistry

Asymmetric synthesis of 3,3′-pyrrolidinyl-dispirooxindoles via a one-pot organocatalytic Mannich/deprotection/aza-Michael sequence

(2016) Kun Zhao et al.   CHEMICAL COMMUNICATIONS

Organocatalytic asymmetric [3+2] cycloaddition of N-2,2,2-trifluoroethylisatin ketimines with 3-alkenyl-5-arylfuran-2(3H)-ones

(2016) Zhen-Hua Wang et al.   CHEMICAL COMMUNICATIONS

Asymmetric synthesis of bicyclic dihydropyrans via organocatalytic inverse-electron-demand oxo-Diels–Alder reactions of enolizable aliphatic aldehydes

(2016) Jun-Long Li et al.   CHEMICAL COMMUNICATIONS

Oxindole: A chemical prism carrying plethora of therapeutic benefits

(2016) Maninder Kaur et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Asymmetric Mannich Reaction of Isatin-Based Ketimines with α-Diazomethylphosphonates Catalyzed by Chiral Silver Phosphate

(2016) Jing Chen et al.   ORGANIC LETTERS

Bifunctional Amine-Squaramides: Powerful Hydrogen-Bonding Organocatalysts for Asymmetric Domino/Cascade Reactions

(2015) Pankaj Chauhan et al.   ADVANCED SYNTHESIS & CATALYSIS

Stereoselective Organocatalytic Synthesis of Oxindoles with Adjacent Tetrasubstituted Stereocenters

(2015) Oliver D. Engl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Deconstructing Covalent Organocatalysis

(2015) Mareike C. Holland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Construction of Vicinal Tetrasubstituted Stereocenters with a C–F Bond through a Catalytic Enantioselective Detrifluoroacetylative Mannich Reaction

(2015) Xihong Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Construction of Vicinal Tetrasubstituted Stereocenters by the Mannich Reaction of Linear α-Substituted Monothiomalonates with Isatin N-Boc Ketimines

(2015) Teng Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

An Organocatalytic Asymmetric Friedel–Crafts Addition/Fluorination Sequence: Construction of Oxindole–Pyrazolone Conjugates Bearing Vicinal Tetrasubstituted Stereocenters

(2015) Xiaoze Bao et al.   ORGANIC LETTERS

A Journey in the Catalytic Synthesis of 3-Substituted 3-Amino­oxindoles

(2015) Jian Zhou et al.   SYNLETT

Asymmetric addition of 3-substituted benzofuran-2-ones to isatin N-Boc ketimines catalyzed by chiral biscinchona alkaloid catalyst

(2015) Yi Zhu et al.   TETRAHEDRON

Towards a stereoselective synthesis of α,α-disubstituted proline analogues

(2015) Sukant K. Das et al.   TETRAHEDRON LETTERS

Stereoselective synthesis of 3-amino-2-oxindoles from isatin imines: new scaffolds for bioactivity evaluation

(2015) Jasneet Kaur et al.   RSC Advances

Enantioselective Construction of Vicinal Tetrasubstituted Stereocenters by the Mannich Reaction of Silyl Ketene Imines with Isatin-Derived Ketimines

(2014) Jiannan Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantioselective synthesis of bisoxindoles with two vicinal quaternary stereocenters via Lewis base mediated addition of oxindoles to isatin-derived ketimines

(2014) Zhongkai Tang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Bifunctional N-Heterocyclic Carbene-Catalyzed Highly Enantioselective Synthesis of Spirocyclic Oxindolo-β-lactams

(2014) Han-Ming Zhang et al.   ORGANIC LETTERS

Palladium-Catalyzed Asymmetric Construction of Vicinal All-Carbon Quaternary Stereocenters and its Application to the Synthesis of Cyclotryptamine Alkaloids

(2013) Barry M. Trost et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure-Activity Relationship Studies of Pyrrolone Antimalarial Agents

(2013) Dinakaran Murugesan et al.   ChemMedChem

Discovery and Structure–Activity Relationships of Pyrrolone Antimalarials

(2013) Dinakaran Murugesan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Construction of Vicinal All-Carbon Quaternary Stereocenters by Catalytic Asymmetric Alkylation Reaction of 3-Bromooxindoles with 3-Substituted Indoles: Total Synthesis of (+)-Perophoramidine

(2013) Hailong Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bifunctional primary amine-thioureas in asymmetric organocatalysis

(2013) Olga V. Serdyuk et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

α-Amino acid derived enaminones and their application in the synthesis of N-protected methyl 5-substituted-4-hydroxypyrrole-3-carboxylates and other heterocycles

(2013) Uroš Grošelj et al.   TETRAHEDRON

Organocatalytic asymmetric synthesis of 3-amino-2-oxindole derivatives bearing a tetra-substituted stereocenter

(2013) Pankaj Chauhan et al.   TETRAHEDRON-ASYMMETRY

Chiral guanidine-catalyzed asymmetric direct vinylogous Michael reaction of α,β-unsaturated γ-butyrolactams with alkylidene malonates

(2012) Yang Yang et al.   CHEMICAL COMMUNICATIONS

α-Oxo-γ-Butyrolactam, N-Containing Pronucleophile in Organocatalytic One-Pot Assembly of Butyrolactam-Fused Indoloquinolizidines

(2012) Hai-Liang Zhu et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic asymmetric direct vinylogous Michael addition of α,β-unsaturated γ-butyrolactam to nitroolefins

(2012) Abhijnan Ray Choudhury et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatins and Their Application in Enantioselective Synthesis of 3-Aminooxindoles

(2012) Wenjin Yan et al.   ORGANIC LETTERS

Squaramides: Bridging from Molecular Recognition to Bifunctional Organocatalysis

(2011) José Alemán et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalyzed enantioselective aldol reaction of 1H-pyrrole-2,3-diones

(2011) Mayur Bhanushali et al.   TETRAHEDRON LETTERS

Pyrrolinone-Based Peptidomimetics. “Let the Enzyme or Receptor be the Judge”

(2010) Amos B. Smith et al.   ACCOUNTS OF CHEMICAL RESEARCH

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Squaramide-Catalyzed Enantioselective Michael Addition of Diphenyl Phosphite to Nitroalkenes

(2009) Ye Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

5-Benzyl-3-methylimidazolidin-4-one-Derived Reactive Intermediates of Organocatalysis - A Comforting Resemblance of X-Ray, NMR, and DFT Solid-Phase, Liquid-Phase, and Gas-Phase Structures

(2009) Uroš Grošelj et al.   HELVETICA CHIMICA ACTA

Chiral Squaramide Derivatives are Excellent Hydrogen Bond Donor Catalysts

(2008) Jeremiah P. Malerich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Non-peptide arginine-vasopressin antagonists: the vaptans

(2008) Guy Decaux et al.   LANCET