Enantioselective Synthesis of Unsymmetrical Diaryl-Substituted Spirocyclohexanonepyrazolones through a Cascade [4+2] Double Michael Addition

Highly Z-Selective Asymmetric Conjugate Addition of Alkynones with Pyrazol-5-ones Promoted by N,N′-Dioxide-Metal Complexes

(2012) Zhen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Construction of Spiro[2H-pyran-3,4′-indoline] by a Systematic Michael/Reduction/Cyclization Sequence Triggered by the Asymmetric Conjugate Addition of Ketones to Isatylidenemalononitriles

(2012) Hua Zhao et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Highly Enantioselective Synthesis of Spiro[cyclohexanone-oxindoles] and Spiro[cyclohexanone-pyrazolones] by Asymmetric Cascade [5+1] Double Michael Reactions

(2012) Bin Wu et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Enantioselective construction of multifunctionalized spirocyclohexaneoxindoles through organocatalytic Michael–Aldol cyclization of isatin derived alkenes with linear dialdehydes

(2012) Xiao-Fei Huang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

ChiralN,N′-Dioxides: New Ligands and Organocatalysts for Catalytic Asymmetric Reactions

(2011) XiaoHua Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Highly Enantioselective Michael Addition of Pyrazolin-5-ones Catalyzed by Chiral Metal/N,N′-Dioxide Complexes: Metal-Directed Switch in Enantioselectivity

(2011) Zhen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Michael/Cyclization Reaction Sequence: Scaffold-Inspired Synthesis of Spirooxindoles with Multiple Stereocenters

(2011) Yiming Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiple Catalysis with Two Chiral Units: An Additional Dimension for Asymmetric Synthesis

(2011) Susy Piovesana et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

Enantioselective methodologies for the synthesis of spiro compounds

(2011) Ramon Rios   CHEMICAL SOCIETY REVIEWS

Organocatalytic Michael-Alkylation Cascade: The Enantioselective Nitrocyclopropanation of Oxindoles

(2011) Fabio Pesciaioli et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Stereoselective Synthesis of Spiropyrazolones

(2011) Andrea-Nekane R. Alba et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A General Organocatalyzed Michael–Michael Cascade Reaction Generates Functionalized Cyclohexenes

(2011) Patrick G. McGarraugh et al.   JOURNAL OF ORGANIC CHEMISTRY

Core-Structure-Motivated Design of a Phosphine-Catalyzed [3 + 2] Cycloaddition Reaction: Enantioselective Syntheses of Spirocyclopenteneoxindoles

(2011) Bin Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective cascade synthesis of spiropyrazolones

(2011) Alex Zea et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic enantioselective pyrazol-3-one addition to maleimides: Reactivity and stereochemical course

(2011) Andrea Mazzanti et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters

(2011) Wen-Bing Chen et al.   ORGANIC LETTERS

Chiral Counteranion Synergistic Organocatalysis under High Temperature: Efficient Construction of Optically Pure Spiro[cyclohexanone-oxindole] Backbone

(2011) Yu-Bao Lan et al.   ORGANIC LETTERS

Organocatalytic Sequential Michael Reactions: Stereoselective Synthesis of Multifunctionalized Tetrahydroindan Derivatives

(2011) Peng He et al.   ORGANIC LETTERS

Highly Stereoselective Brønsted Acid Catalyzed Synthesis of Spirooxindole Pyrans

(2011) Jingqi Wang et al.   ORGANIC LETTERS

Catalytic Asymmetric Construction of Spirocyclopentaneoxindoles by a Combined Ru-Catalyzed Cross-Metathesis/Double Michael Addition Sequence

(2011) Ying-Mei Li et al.   ORGANIC LETTERS

Highly Enantioselective One-Pot Synthesis of Spirocyclopentaneoxindoles Containing the Oxime Group by Organocatalyzed Michael Addition/ISOC/Fragmentation Sequence

(2011) Xiang Li et al.   ORGANIC LETTERS

Asymmetric α-Amination of 4-Substituted Pyrazolones Catalyzed by a Chiral Gd(OTf)3/N,N′-Dioxide Complex: Highly Enantioselective Synthesis of 4-Amino-5-pyrazolone Derivatives

(2011) Zhigang Yang et al.   ORGANIC LETTERS

Asymmetic Organocatalytic 1,3-Dipolar Cycloaddition of Azomethine Ylide to Methyl 2-(2-Nitrophenyl)acrylate for the Synthesis of Diastereoisomers of Spirotryprostatin A

(2011) Mou-Nuo Cheng et al.   ORGANIC LETTERS

Asymmetric synthesis of multi-substituted spiro[5,5]undecane-1,5,9-triones via organocatalytic three-component reaction

(2011) Jian Shi et al.   TETRAHEDRON

Recent advances in asymmetric catalysis with cinchona alkaloid-based primary amines

(2011) Lin Jiang et al.   Catalysis Science & Technology

Enantioselective Synthesis of Spirocyclic Oxindole-β-lactones via N-Heterocyclic Carbene-Catalyzed Cycloaddition of Ketenes and Isatins

(2010) Xiao-Na Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocatalytic Asymmetric Michael Addition of Pyrazolin-5-ones to Nitroolefins with Bifunctional Thiourea: Stereocontrolled Construction of Contiguous Quaternary and Tertiary Stereocenters

(2010) Yu-Hua Liao et al.   ADVANCED SYNTHESIS & CATALYSIS

Cooperative Organocatalysis for the Asymmetric γ Alkylation of α-Branched Enals

(2010) Giulia Bergonzini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiple approaches to enantiopure spirocyclic benzofuranones using organocatalytic cascade reactions

(2010) Carlo Cassani et al.   CHEMICAL COMMUNICATIONS

A Unique Approach to the Concise Synthesis of Highly Optically Active Spirooxazolines and the Discovery of a More Potent Oxindole-Type Phytoalexin Analogue

(2010) Xianxing Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Epoxidation of α-Branched Enals

(2010) Olga Lifchits et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Microwave-Assisted One-Pot Synthesis of Pyrazolone Derivatives under Solvent-Free Conditions

(2010) Ruoqun Ma et al.   MOLECULES

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Primary Amine/(+)-CSA Salt-Promoted Organocatalytic Conjugate Addition of Nitro Esters to Enones

(2010) Chen Liu et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Formal [4 + 2] Cycloaddition for the Synthesis of Spiro[4-cyclohexanone-1,3′-oxindoline] Derivatives in High Optical Purity

(2010) Qiang Wei et al.   ORGANIC LETTERS

Highly Enantioselective Construction of Spiro[4H-pyran-3,3′-oxindoles] Through a Domino Knoevenagel/Michael/Cyclization Sequence Catalyzed by Cupreine

(2010) Wen-Bing Chen et al.   ORGANIC LETTERS

Cinchona Alkaloids in Asymmetric Organocatalysis

(2010) Tommaso Marcelli et al.   SYNTHESIS-STUTTGART

Efficient Method for the Synthesis of Optically Active 2-Amino-2-chromene Derivatives via One-Pot Tandem Reactions

(2009) Jian-Wu Xie et al.   ADVANCED SYNTHESIS & CATALYSIS

Organocascade Reactions of Enones Catalyzed by a Chiral Primary Amine

(2009) Li-Yuan Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting Structural and Stereochemical Complexity by Organocascade Catalysis: Construction of Spirocyclic Oxindoles Having Multiple Stereocenters

(2009) Giorgio Bencivenni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and antiviral activity of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) against peste des petits ruminant virus (PPRV)

(2009) Kuppusamy Sujatha et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Asymmetric catalysis with chiral primary amine-based organocatalysts

(2009) Li-Wen Xu et al.   CHEMICAL COMMUNICATIONS

Organocatalytic Domino Reactions

(2009) Andrea-Nekane Alba et al.   CURRENT ORGANIC CHEMISTRY

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

(2009) Xiao-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of Spirooxindoles by Palladium-Catalyzed Decarboxylative Cyclization of γ-Methylidene-δ-valerolactones with Isatins

(2009) Ryo Shintani et al.   ORGANIC LETTERS

Stereoselective Synthesis of Spirocyclic Oxindoles via Prins Cyclizations

(2009) M. Paola Castaldi et al.   ORGANIC LETTERS

Stereocontrolled Synthesis of Spirooxindoles through Lewis Acid-Promoted [5 + 2]-Annulation of Chiral Silyl Alcohols

(2009) Yun Zhang et al.   ORGANIC LETTERS

Sodium stearate-catalyzed multicomponent reactions for efficient synthesis of spirooxindoles in aqueous micellar media

(2009) Li-Min Wang et al.   TETRAHEDRON

Organocatalytic Asymmetric Formal [3+3] Cycloaddition Reactions of α,β-Unsaturated Aldehydes with Nazarov Reagents

(2008) Ming-Kui Zhu et al.   ADVANCED SYNTHESIS & CATALYSIS

Natural Products, Small Molecules, and Genetics in Tuberculosis Drug Development

(2008) Maria-Teresa Gutierrez-Lugo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Enantioselective Diels−Alder Reaction of Simple α,β-Unsaturated Ketones with a Cinchona Alkaloid Catalyst

(2008) Ravi P. Singh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Epoxidation of Cyclic Enones

(2008) Xingwang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Peroxidation of α,β-Unsaturated Ketones

(2008) Xiaojie Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective desymmetrisation of prochiral α,α-dicyanoalkenes via domino Michael–Michael addition reactions

(2008) Tai-Ran Kang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The Development of Asymmetric Primary Amine Catalysts Based on Cinchona Alkaloids

(2008) Ying-Chun Chen   SYNLETT

Organocatalytic Asymmetric Sulfa-Michael Addition to α,β-Unsaturated Ketones

(2007) Paolo Ricci et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Counteranion-Directed Catalysis for the Epoxidation of Enals

(2007) Xingwang Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and antimicrobial activity of some new heterocycles incorporating antipyrine moiety

(2007) Samir Bondock et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New Pd(II) and Pt(II) complexes with N,S-chelated pyrazolonate ligands: Molecular and supramolecular structure and preliminary study of their in vitro antitumoral activity

(2007) José S. Casas et al.   JOURNAL OF INORGANIC BIOCHEMISTRY