4.6 Article

Microwave-Assisted One-Pot Synthesis of Pyrazolone Derivatives under Solvent-Free Conditions

Journal

MOLECULES
Volume 15, Issue 5, Pages 3593-3601

Publisher

MDPI
DOI: 10.3390/molecules15053593

Keywords

microwave-assisted reactions; one-pot; pyrazolones

Funding

  1. National Natural Science Foundation of China [90813005, 20902022, 30801415, 30890044]
  2. Open Project Program of State Key Laboratory of Drug Research [SIMM0901KF-03]
  3. Shanghai Rising-Star Program [09QA1406800]

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An efficient one-pot method to generate structurally diverse and medicinally interesting pyrazolone derivatives in good to excellent yields of 51-98% under microwave irradiation and solvent-free conditions has been developed.

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