Journal
ORGANIC LETTERS
Volume 10, Issue 9, Pages 1731-1734Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol8003589
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A direct asymmetric organocatalytic aza-Henry reaction has been developed in which a new bifuctional Bronsted-acid-catalyzed activation of nitroalkanes provides an efficient access to alpha,beta-diamino acids with high dia- and enantioselectivities under mild and base-free reaction conditions.
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