Bioresponsive Nanoparticles Targeted to Infectious Microenvironments for Sepsis Management

Green Fabrication of Amphiphilic Quaternized β-Chitin Derivatives with Excellent Biocompatibility and Antibacterial Activities for Wound Healing

(2018) Huan Xu et al.   ADVANCED MATERIALS

Metal-Organic-Framework-Assisted In Vivo Bacterial Metabolic Labeling and Precise Antibacterial Therapy

(2018) Duo Mao et al.   ADVANCED MATERIALS

Antibiotic-loaded nanoparticles targeted to the site of infection enhance antibacterial efficacy

(2018) Sazid Hussain et al.   Nature Biomedical Engineering

Ciprofloxacin-loaded PLGA nanoparticles against cystic fibrosis P. aeruginosa lung infections

(2017) Nazende Günday Türeli et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Ciprofloxacin-loaded lipid-core nanocapsules as mucus penetrating drug delivery system intended for the treatment of bacterial infections in cystic fibrosis

(2017) Afra Torge et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Selective killing ofHelicobacter pyloriwith pH-responsive helix–coil conformation transitionable antimicrobial polypeptides

(2017) Menghua Xiong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management

(2017) Soracha Thamphiwatana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release

(2016) Nazila Kamaly et al.   CHEMICAL REVIEWS

Encapsulation of NSAIDs for inflammation management: Overview, progress, challenges and prospects

(2016) Waisudin Badri et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Cell membrane-formed nanovesicles for disease-targeted delivery

(2016) Jin Gao et al.   JOURNAL OF CONTROLLED RELEASE

Biomimetic proteolipid vesicles for targeting inflamed tissues

(2016) R. Molinaro et al.   NATURE MATERIALS

Neutrophil-Mediated Delivery of Therapeutic Nanoparticles across Blood Vessel Barrier for Treatment of Inflammation and Infection

(2015) Dafeng Chu et al.   ACS Nano

pH-Activated Nanoparticles for Controlled Topical Delivery of Farnesol To Disrupt Oral Biofilm Virulence

(2015) Benjamin Horev et al.   ACS Nano

Amphiphilic Star Copolymer-Based Bimodal Fluorogenic/Magnetic Resonance Probes for Concomitant Bacteria Detection and Inhibition

(2014) Yamin Li et al.   ADVANCED MATERIALS

Sepsis: Current Dogma and New Perspectives

(2014) Clifford S. Deutschman et al.   IMMUNITY

Prevention of vascular inflammation by nanoparticle targeting of adherent neutrophils

(2014) Zhenjia Wang et al.   Nature Nanotechnology

Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

(2014) Samir Mitragotri et al.   NATURE REVIEWS DRUG DISCOVERY

Strategies to improve drug development for sepsis

(2014) Mitchell P. Fink et al.   NATURE REVIEWS DRUG DISCOVERY

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

(2014) Vladimir P. Torchilin   NATURE REVIEWS DRUG DISCOVERY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding

(2013) Kendra N. Iskander et al.   PHYSIOLOGICAL REVIEWS

Epidemiology of severe sepsis

(2013) Florian B Mayr et al.   Virulence

Surface Charge-Switching Polymeric Nanoparticles for Bacterial Cell Wall-Targeted Delivery of Antibiotics

(2012) Aleksandar F. Radovic-Moreno et al.   ACS Nano

Bacteria-Responsive Multifunctional Nanogel for Targeted Antibiotic Delivery

(2012) Meng-Hua Xiong et al.   ADVANCED MATERIALS

Sepsis, severe sepsis and septic shock: changes in incidence, pathogens and outcomes

(2012) Greg S Martin   Expert Review of Anti-Infective Therapy

The acute respiratory distress syndrome

(2012) Michael A. Matthay et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipase-Sensitive Polymeric Triple-Layered Nanogel for “On-Demand” Drug Delivery

(2012) Meng-Hua Xiong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Negligible Particle-Specific Antibacterial Activity of Silver Nanoparticles

(2012) Zong-ming Xiu et al.   NANO LETTERS

Nanoparticle Delivery of Cancer Drugs

(2011) Andrew Z. Wang et al.   Annual Review of Medicine

The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment

(2011) Michael A. Matthay et al.   Annual Review of Pathology-Mechanisms of Disease

Delivery of nanoparticle-complexed drugs across the vascular endothelial barrier via caveolae

(2011) Zhenjia Wang et al.   IUBMB LIFE

Bacterial Toxin-Triggered Drug Release from Gold Nanoparticle-Stabilized Liposomes for the Treatment of Bacterial Infection

(2011) Dissaya Pornpattananangkul et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The neutrophil in vascular inflammation

(2011) Mia Phillipson et al.   NATURE MEDICINE

Anti-inflammatory Agents: Present and Future

(2010) Charles A. Dinarello   CELL

An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells

(2010) Woo-Yong Lee et al.   NATURE IMMUNOLOGY

Impact of Nanotechnology on Drug Delivery

(2009) Omid C. Farokhzad et al.   ACS Nano

pH-Responsive composite based on prednisone-block copolymer micelle intercalated inorganic layered matrix: Structure and in vitro drug release

(2009) Yong Li et al.   CHEMICAL ENGINEERING JOURNAL

Update on the treatment of Pseudomonas aeruginosa pneumonia

(2009) A. A. El Solh et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Mechanisms of Cation Exchange by Pseudomonas aeruginosa PAO1 and PAO1 wbpL, a Strain with a Truncated Lipopolysaccharide

(2008) J. Shephard et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE