New physiologically-relevant liver tissue model based on hierarchically cocultured primary rat hepatocytes with liver endothelial cells

Oxygen-permeable membrane-based direct oxygenation remarkably enhances functions and gene expressions of rat hepatocytes in both 3D and sandwich cultures

(2014) Wenjin Xiao et al.   BIOCHEMICAL ENGINEERING JOURNAL

The importance of physiological oxygen concentrations in the sandwich cultures of rat hepatocytes on gas-permeable membranes

(2014) Wenjin Xiao et al.   BIOTECHNOLOGY PROGRESS

Sandwich-cultured hepatocytes: utility forin vitroexploration of hepatobiliary drug disposition and drug-induced hepatotoxicity

(2013) Tom De Bruyn et al.   Expert Opinion on Drug Metabolism & Toxicology

Designing a Multicellular Organotypic 3D Liver Model with a Detachable, Nanoscale Polymeric Space of Disse

(2013) Adam L. Larkin et al.   TISSUE ENGINEERING PART C-METHODS

Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies

(2012) J. Fraczek et al.   ARCHIVES OF TOXICOLOGY

Enhanced bile canaliculi formation enabling direct recovery of biliary metabolites of hepatocytes in 3D collagen gel microcavities

(2012) Hitoshi Matsui et al.   LAB ON A CHIP

Gas-permeable membranes and co-culture with fibroblasts enable high-density hepatocyte culture as multilayered liver tissues

(2011) Fanny Evenou et al.   BIOTECHNOLOGY PROGRESS

Key role of sinusoidal endothelial cells in the triggering of liver regeneration

(2011) Nicolas Moniaux et al.   JOURNAL OF HEPATOLOGY

Merging bioreactor technology with 3D hepatocyte-fibroblast culturing approaches: Improved in vitro models for toxicological applications

(2011) Sofia B. Leite et al.   TOXICOLOGY IN VITRO

Rapid and enhanced repolarization in sandwich-cultured hepatocytes on an oxygen-permeable membrane

(2010) Hitoshi Matsui et al.   BIOCHEMICAL ENGINEERING JOURNAL

Engineering of an Hepatic Organoid to Develop Liver Assist Devices

(2010) Alejandro Soto-Gutierrez et al.   CELL TRANSPLANTATION

3D Hepatic Cultures Simultaneously Maintain Primary Hepatocyte and Liver Sinusoidal Endothelial Cell Phenotypes

(2010) Yeonhee Kim et al.   PLoS One

The Design of In Vitro Liver Sinusoid Mimics Using Chitosan–Hyaluronic Acid Polyelectrolyte Multilayers

(2010) Yeonhee Kim et al.   TISSUE ENGINEERING PART A

Amino acid-mediated heterotypic interaction governs performance of a hepatic tissue model

(2009) Rohit Jindal et al.   FASEB JOURNAL

Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro

(2009) Sandra March et al.   HEPATOLOGY

Oxygen-mediated enhancement of primary hepatocyte metabolism, functional polarization, gene expression, and drug clearance

(2009) S. Kidambi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal Breast Cancer Resistance Protein (BCRP)/Bcrp1 and Multidrug Resistance Protein 3 (MRP3)/Mrp3 Are Involved in the Pharmacokinetics of Resveratrol

(2008) K. van de Wetering et al.   MOLECULAR PHARMACOLOGY

Stable immobilization of rat hepatocytes as hemispheroids onto collagen-conjugated poly-dimethylsiloxane (PDMS) surfaces: Importance of direct oxygenation through PDMS for both formation and function

(2007) Masaki Nishikawa et al.   BIOTECHNOLOGY AND BIOENGINEERING

Enhanced maintenance and functions of rat hepatocytes induced by combination of on-site oxygenation and coculture with fibroblasts

(2007) Masaki Nishikawa et al.   JOURNAL OF BIOTECHNOLOGY