Article
Engineering, Civil
Muhammad Waqar, Moez Louati, Mohamed S. Ghidaoui
Summary: Time reversal (TR) techniques are widely used and robust to damping, allowing for applications in various fields including medical treatment, material detection, and communication. This paper investigates the applicability of TR-based methods for damped water-hammer waves and shows that while the spatial resolution is maintained, damping reduces the amplitude of the refocused wave, potentially affecting resolution in the presence of noise.
JOURNAL OF HYDRAULIC RESEARCH
(2022)
Article
Gastroenterology & Hepatology
M. Climent, R. Frago, N. Cornella, M. Serrano, E. Kreisler, S. Biondo
Summary: This study evaluated the morbidity related to loop ileostomy closure, finding that patients with chronic kidney disease, those who had any complication after primary surgery, and those who had ileostomy closure later than 10 months after primary surgery had a significantly higher risk of developing postoperative complications.
TECHNIQUES IN COLOPROCTOLOGY
(2022)
Article
Acoustics
Murat M. Gozum, Saber Nasraoui, Georgios Grigoropoulos, Moez Louati, Mohamed S. Ghidaoui
Summary: This paper introduces a high-resolution, passive defect detection technique for pressurized water supply pipeline systems (PWSPS) using the ubiquitous high-frequency background noise in the systems. By measuring the background noise at two locations along the pipe, the technique enables accurate defect detection and localization, which is important for buried and inaccessible pipeline systems.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2022)
Article
Critical Care Medicine
Jay Chandra, Miguel A. Armengol de la Hoz, Gwendolyn Lee, Alexandria Lee, Patrick Thoral, Paul Elbers, Hyung-Chul Lee, John S. Munger, Leo Anthony Celi, David A. Kaufman
Summary: This study aims to quantify vascular leak in sepsis patients and guide fluid resuscitation.
Article
Multidisciplinary Sciences
In-Gu Do, Kyung Uk Jung, Dong-Hoe Koo, Yun-Gyoo Lee, Sukjoong Oh, Kyungeun Kim, Dong-Hoon Kim, Jin Hee Sohn, Byung Ho Son, Sung Ryol Lee, Jun Ho Shin, Hyung Ook Kim, Hungdai Kim, Ho-Kyung Chun, Ginette Serrero, Chang Hak Yoo
Summary: This study retrospectively analyzed 54 patients with GIST who underwent curative surgical resection, and found that high PGRN expression was associated with worse prognosis, characterized by more epithelioid/mixed histology and KIT exon 11 mutations.
Article
Surgery
Mahmoud B. Malas, Hanaa Dakour-Aridi, Vikram S. Kashyap, Jens Eldrup-Jorgensen, Grace J. Wang, Raghu L. Motaganahalli, Jack L. Cronenwett, Marc L. Schermerhorn
Summary: This study compared the outcomes of TCAR with flow reversal to the gold standard CEA and found that TCAR significantly reduces the risk of postoperative myocardial infarction and cranial nerve injury compared to CEA, with no differences in the rates of stroke/death.
Article
Gastroenterology & Hepatology
S. Lindner, K. von Rudno, J. Gawlitza, J. Hardt, F. Sandra-Petrescu, S. Seyfried, P. Kienle, C. Reissfelder, A. Bogner, F. Herrle
Summary: This study aimed to investigate whether contrast enema and flexible endoscopy should be routinely performed before ileostomy reversal after low anterior resection, and to assess the impact of previous anastomotic leakage on diagnostic test accuracy. The results showed that flexible endoscopy is the more accurate diagnostic test for the detection of asymptomatic anastomotic leaks, with no gain of information from contrast enema.
INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
(2021)
Review
Pharmacology & Pharmacy
Usamah S. Kayyali, Elizabeth Ghandakly, Natesh Singh, Bruno O. Villoutreix, Katya Tsaioun
Summary: The endothelial vascular permeability barrier plays an important role in the body's vasculature, and disruption can lead to vascular hyperpermeability. In the lungs, vascular hyperpermeability can cause pulmonary edema and acute respiratory distress syndrome (ARDS). Currently, there is no pharmacological treatment for ARDS, but enhancing the endothelial barrier may be a potential approach for treating ARDS and other conditions associated with vascular hyperpermeability.
DRUG DISCOVERY TODAY
(2022)
Article
Biochemistry & Molecular Biology
Ruirui Wang, Chen Ni, Xiaohan Lou, Lijing Zhang, Linlin Wang, Xiaohan Yao, Xixi Duan, Jiajia Wan, Pan Li, Zhihai Qin
Summary: This study found that treatment with cisplatin often caused IFN gamma-dependent tumor vascular damage. The researchers developed nanoparticles that targeted the leakage site of damaged tumor blood vessels and blocked IFN gamma activity, promoting blood vessel integrity and drug delivery.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES
(2023)
Article
Oncology
Thomas L. Sutton, Brett S. Walker, Kevin G. Billingsley, Brett C. Sheppard, Christopher L. Corless, Michael C. Heinrich, Skye C. Mayo
Summary: Longer disease-free interval (DFI) exceeding 24 months in GIST patients is independently associated with higher post-recurrence survival rate and better progression-free survival rate at 10 years. DFI duration may be linked to tumor biology characteristics and treatment planning.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Oncology
You-Zhu Wei, Zhi-Bin Cai, Chen-Long Zhu, Yan-Ming Zhou, Xiao-Feng Zhang
Summary: The study evaluated the long-term survival outcomes of patients with duodenal GIST who underwent radical resection (RR) or limited resection (LR). Results showed that surgical modalities did not have a significant impact on long-term survival outcomes, which should mainly depend on tumor size and location.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Article
Surgery
Danielle Taylor, Ian G. Faragher, Mobin Master, Stephanie Wang, Steven T. F. Chan, Justin M. C. Yeung
Summary: This study proposed a classification system for chronic rectal anastomotic complications and examined the correlation with outcomes after ileostomy reversal. The results showed that patients with Type 1 stenosis or defect had few rectal complications after stoma closure.
ANZ JOURNAL OF SURGERY
(2022)
Article
Multidisciplinary Sciences
Francesco Mongelli, Fabio Garofalo, Pietro Giacopelli, Martino Munini, Francesco Volonte, Michele Marengo
Summary: Our study aimed to assess the usefulness of indocyanine green (ICG) angiography in reoperative bariatric surgery. We compared patients who received ICG with a retrospective group who did not. The results indicated that ICG angiography may not be useful for evaluating blood supply in gastric pouch resizing during reoperative bariatric surgery. Therefore, further research is needed to determine the appropriate use of this technique.
SCIENTIFIC REPORTS
(2023)
Article
Peripheral Vascular Disease
Joana Amado-Azevedo, Anne-Marieke D. van Stalborch, Erik T. Valent, Kalim Nawaz, Jan van Bezu, Etto C. Eringa, Femke P. M. Hoevenaars, Iris M. De Cuyper, Peter L. Hordijk, Victor W. M. van Hinsbergh, Geerten P. van Nieuw Amerongen, Jurjan Aman, Coert Margadant
Summary: The kinase Arg/Abl2 has been identified as a mediator of endothelial barrier disruption. Depletion of Arg in endothelial cells resulted in activation of RhoA and Rac1, increased cell spreading and elongation, and redistribution of integrin-dependent cell-matrix adhesions. In vivo, genetic deletion of Arg diminished vascular leak in the skin and lungs, suggesting therapeutic inhibition of Arg may be a feasible strategy for treating conditions characterized by vascular leak.
Article
Engineering, Multidisciplinary
Jaehyun Yang, Hamid Mostaghimi, Ron Hugo, Simon S. Park
Summary: This study introduces a comprehensive leak monitoring system that allows leak detection, localization, and volume rate estimation in liquid pipelines. The system uses artificial intelligence algorithms for leak detection and pressure sensors and accelerometers to capture real-time variations of fluid pressure and vibrations of the pipeline. Experimental results show high accuracy in leak detection, localization, and leak volume rate estimation.