Review
Genetics & Heredity
Maciej Tarnowski, Patrycja Kopytko, Katarzyna Piotrowska
Summary: Epigenetic modifications in response to environmental changes play a fundamental role in gene expression regulation. In the context of physical activity, the inflammatory response triggered by PA is considered a vital trigger for epigenetic changes that modulate inflammatory actions.
Review
Cell Biology
Omar Ramos-Lopez, Fermin I. Milagro, Jose I. Riezu-Boj, J. Alfredo Martinez
Summary: This review highlights the harmful effects of external factors like high-fat/high-sugar diets, micronutrient deficiencies, obesity, infections, smoking, etc., on inflammation through epigenetic mechanisms, while also discussing the potential anti-inflammatory effects of nutrients and exercise.
INFLAMMATION RESEARCH
(2021)
Article
Sport Sciences
Anna Kankaanpaa, Asko Tolvanen, Sailalitha Bollepalli, Tuija Leskinen, Urho M. Kujala, Jaakko Kaprio, Miina Ollikainen, Elina Sillanpaa
Summary: The study found that greater leisure-time physical activity was associated with slower epigenetic aging, while occupational physical activity was linked to faster epigenetic aging. However, these associations were attenuated after adjusting for smoking status.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2021)
Article
Cell Biology
Fabienne A. U. Fox, Dan Liu, Monique M. B. Breteler, Nasir Ahmad Aziz
Summary: Physical activity is associated with slower epigenetic ageing through its effects on immune function and cardiovascular health. Additionally, specific CpG sites were identified to be associated with physical activity, further supporting the link between physical activity and epigenetic ageing.
Review
Oncology
Vicente Javier Clemente-Suarez, Alexandra Martin-Rodriguez, Laura Redondo-Florez, Pablo Ruisoto, Eduardo Navarro-Jimenez, Domingo Jesus Ramos-Campo, Jose Francisco Tornero-Aguilera
Summary: Recent research suggests a strong link between the functioning of mitochondria and the development of cancer. Healthy mitochondria play a vital role in maintaining metabolic processes and controlling cell death, but inflammation can harm their function and lead to tissue damage. Engaging in both endurance and resistance exercises, in addition to maintaining an active lifestyle, can help improve mitochondrial functioning and reduce the risk of cancer.
Article
Biochemistry & Molecular Biology
Mathilde Mura, Michele Weiss-Gayet, Nellie Della-Schiava, Erica Chirico, Patrick Lermusiaux, Marie Chambion-Diaz, Camille Faes, Anaelle Boreau, Benedicte Chazaud, Antoine Millon, Vincent Pialoux
Summary: Atherosclerosis is associated with chronic inflammation involving circulating monocytes. Physical activity has been shown to decrease inflammation and the risk of stroke. This study found that moderately active patients had a lower percentage of classical and intermediate monocytes compared to non-active and highly active patients. In contrast, the percentage of non-classical monocytes increased in moderately active patients. These findings suggest that physical activity can be beneficial for patients by reducing the risk of ischemic stroke and promoting lesion healing.
Article
Economics
Sefa Awaworyi Churchill, Isaac Koomson, Musharavati Ephraim Munyanyi
Summary: This study utilizes 16 waves of longitudinal data to investigate the relationship between transport poverty and obesity in Australia. The findings suggest that transport poverty is associated with a decline in obesity, and social capital and physical activity are identified as potential mechanisms through which this relationship occurs. These results highlight the importance of implementing policies that promote social capital and physical activity to address the increasing concerns about obesity.
Review
Cardiac & Cardiovascular Systems
Amedeo Tirandi, Fabrizio Montecucco, Luca Liberale
Summary: The amount of physical activity practiced by people has been decreasing in recent decades, leading to higher risks of atherosclerosis and related cardiovascular events. Regular physical activity has beneficial effects on metabolism and can help prevent cardiovascular diseases. Several studies have found lower levels of plasma lipids in individuals who engage in exercise, but the exact mechanisms by which physical activity modulates lipoproteins are still not fully understood.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Biology
Sergey K. Sudakov, Natalia G. Bogdanova, Galina A. Nazarova
Summary: This research investigates the influence of epigenetic events at conception on the formation of behavioral features in adult rats. The study examines the first generational inheritance of activity level, anxiety-like behavior, and learning ability. The results show that offspring of parents who mated in the presence of males with high motor activity display higher activity levels, but anxiety-like behavior and learning ability are not inherited in the same way. This discovery may be important for maintaining a specific population's activity levels and counteracting natural selection.
Article
Sport Sciences
Nicole L. Spartano, Ruiqi Wang, Qiong Yang, Ariel Chernofsky, Joanne M. Murabito, Ramachandran S. Vasan, Daniel Levy, Alexa S. Beiser, Sudha Seshadri
Summary: Habitual physical activity and sedentary time are associated with epigenetic age, which is partially explained by BMI. Future research should explore whether changes in physical activity influence methylation status and whether those modifications influence chronic disease risk.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2023)
Article
Public, Environmental & Occupational Health
Jessica Stroope, Alex Garn, Lisa Cadmus-Bertram
Summary: There is a positive relationship between active transportation and maintaining or increasing physical activity, especially for older adults. This study provides further evidence of the importance of creating built environments and policies supportive of active transportation.
JOURNAL OF TRANSPORT & HEALTH
(2022)
Article
Geriatrics & Gerontology
Nandini Mukherjee, Tracie C. Harrison
Summary: This study is the first to compare the associations between epigenetic age estimates and the prevalence of rheumatoid arthritis (RA). The results show that epigenetic age acceleration is significantly associated with RA, with RA patients showing higher biological age acceleration compared to healthy controls.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2023)
Article
Psychology, Clinical
Katrien De Cocker, Stuart J. H. Biddle, Megan J. Teychenne, Jason A. Bennie
Summary: The study found favorable associations between any domain (leisure-time, transport- and work-related) of physical activity and depressive symptom severity. Any level of physical activity in any domain was mostly associated with a lower prevalence of moderate, moderate-severe, and severe depressive symptoms. Both modalities of leisure-time physical activity (aerobic and muscle-strengthening) demonstrated beneficial associations with depression, but slightly more so for aerobic physical activity.
DEPRESSION AND ANXIETY
(2021)
Article
Psychology, Developmental
Emily M. . D'Agostino, Sarah C. Armstrong, Emily P. Alexander, Truls Ostbye, Cody D. Neshteruk, Asheley C. Skinner
Summary: The study found that males, minority groups, and low-income youth are more likely to choose active transportation, while young people from lower-income families and educational backgrounds are more likely to choose active transportation daily. There is an inverse relationship between weight class and participation in active transportation.
JOURNAL OF ADOLESCENT HEALTH
(2021)
Review
Physiology
Joseph A. Taylor, Paul L. Greenhaff, David B. Bartlett, Thomas A. Jackson, Niharika A. Duggal, Janet M. Lord
Summary: Frailty is a state characterized by increased vulnerability and decreased ability to recover from stress compared to non-frailty. It is important to understand the clinical and physiological features of frailty, as well as the factors driving it, due to the increasing life expectancy and prevalence of physical frailty.
PHYSIOLOGICAL REVIEWS
(2023)
Article
Substance Abuse
R. Colin Carter, Jia Chen, Qian Li, Maya Deyssenroth, Neil C. Dodge, Helen C. Wainwright, Christopher D. Molteno, Ernesta M. Meintjes, Joseph L. Jacobson, Sandra W. Jacobson
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH
(2018)
Article
Endocrinology & Metabolism
W. Zhang, Q. Li, M. Deyssenroth, L. Lambertini, J. Finik, J. Ham, Y. Huang, K. J. Tsuchiya, P. Pehme, J. Buthmann, S. Yoshida, J. Chen, Y. Nomura
JOURNAL OF NEUROENDOCRINOLOGY
(2018)
Article
Pediatrics
Julia F. Litzky, Maya A. Deyssenroth, Todd M. Everson, Barry M. Lester, Luca Lambertini, Jia Chen, Carmen J. Marsit
PEDIATRIC RESEARCH
(2018)
Article
Environmental Sciences
Maya A. Deyssenroth, Chris Gennings, Shelley H. Liu, Shouneng Peng, Ke Hao, Luca Lambertini, Brian P. Jackson, Margaret R. Karagas, Carmen J. Marsit, Jia Chen
ENVIRONMENT INTERNATIONAL
(2018)
Article
Genetics & Heredity
Shouneng Peng, Maya A. Deyssenroth, Antonio F. Di Narzo, Haoxiang Cheng, Zhongyang Zhang, Luca Lambertini, Arno Rusualepp, Jason C. Kovacic, Johan L. M. Bjorkegren, Carmen J. Marsit, Jia Chen, Ke Hao
Article
Environmental Sciences
Todd M. Everson, Carmen Marable, Maya A. Deyssenroth, Tracy Punshon, Brian P. Jackson, Luca Lambertini, Margaret R. Karagas, Jia Chen, Carmen J. Marsit
ENVIRONMENTAL HEALTH PERSPECTIVES
(2019)
Article
Multidisciplinary Sciences
Danielle A. Clarkson-Townsend, Todd M. Everson, Maya A. Deyssenroth, Amber A. Burt, Karen E. Hermetz, Ke Hao, Jia Chen, Carmen J. Marsit
Article
Biochemistry & Molecular Biology
Maya A. Deyssenroth, Carmen J. Marsit, Jia Chen, Luca Lambertini
Article
Environmental Sciences
Matthew Mazzella, Susan J. Sumner, Shangzhi Gao, Li Su, Nancy Diao, Golam Mostofa, Qazi Qamruzzaman, Wimal Pathmasiri, David C. Christiani, Timothy Fennell, Chris Gennings, Maya A. Deyssenroth, Elena Colicino, Paul Curtin, Megan M. Niedzwiecki
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2020)
Article
Multidisciplinary Sciences
Wei Zhang, Jacob Ham, Qian Li, Maya A. Deyssenroth, Luca Lambertini, Yonglin Huang, Kenji J. Tsuchiya, Jia Chen, Yoko Nomura
Article
Biochemistry & Molecular Biology
Danielle A. Clarkson-Townsend, Elizabeth Kennedy, Todd M. Everson, Maya A. Deyssenroth, Amber A. Burt, Ke Hao, Jia Chen, Machelle T. Lardue, Carmen J. Marsit
Article
Developmental Biology
Whitney Cowell, Maya Deyssenroth, Jia Chen, Rosalind J. Wright
Article
Biochemistry & Molecular Biology
Elizabeth M. Kennedy, Karen Hermetz, Amber Burt, Todd M. Everson, Maya Deyssenroth, Ke Hao, Jia Chen, Margaret R. Karagas, Dong Pei, Devin C. Koestler, Carmen J. Marsit
Summary: The study reveals that MicroRNAs play a role in regulating trophoblast biology in the placenta, with certain MicroRNAs associated with fetal growth. miR-532 is positively correlated with infant birthweight percentile (BWP) and influences BWP through regulation of adipocytokines such as Leptin and Adiponectin.
Article
Genetics & Heredity
Maya A. Deyssenroth, Qian Li, Carlos Escudero, Leslie Myatt, Jia Chen, James M. Roberts
Article
Genetics & Heredity
Michael R. Hussey, Amber Burt, Maya A. Deyssenroth, Brian P. Jackson, Ke Hao, Shouneng Peng, Jia Chen, Carmen J. Marsit, Todd M. Everson
ENVIRONMENTAL EPIGENETICS
(2020)