Mitochondrial translocation of Nur77 mediates cardiomyocyte apoptosis

Regulation of Nur77 protein turnover through acetylation and deacetylation induced by p300 and HDAC1

(2010) Shin-Ae Kang et al.   BIOCHEMICAL PHARMACOLOGY

Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis

(2010) Jennifer Thompson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Involvement of induction and mitochondrial targeting of orphan nuclear receptor Nur77 in 6-OHDA-induced SH-SY5Y cell death

(2010) Haja No et al.   NEUROCHEMISTRY INTERNATIONAL

The role of the mitochondrial permeability transition pore in heart disease

(2009) Andrew P. Halestrap et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Identification of Nuclear Export Inhibitors with Potent Anticancer Activity In vivo

(2009) S. C. Mutka et al.   CANCER RESEARCH

NGFI-B targets mitochondria and induces cardiomyocyte apoptosis in restraint-stressed rats by mediating energy metabolism disorder

(2009) XinXing Wang et al.   CELL STRESS & CHAPERONES

Heart Disease and Stroke Statistics—2010 Update

(2009) et al.   CIRCULATION

Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes

(2009) Marta Rubio et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A Short Nur77-Derived Peptide Converts Bcl-2 from a Protector to a Killer

(2008) Siva Kumar Kolluri et al.   CANCER CELL

Modulation of Orphan Nuclear Receptor Nur77-Mediated Apoptotic Pathway by Acetylshikonin and Analogues

(2008) Jie Liu et al.   CANCER RESEARCH

During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain

(2008) Jennifer Thompson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Induction of Orphan Nuclear Receptor Nur77 Expression by n-Butylenephthalide as Pharmaceuticals on Hepatocellular Carcinoma Cell Therapy

(2008) Y.-L. Chen et al.   MOLECULAR PHARMACOLOGY