Structure and evolution of double minutes in diagnosis and relapse brain tumors

Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma

(2018) Ana C. deCarvalho et al.   NATURE GENETICS

Discoveries of Extrachromosomal Circles of DNA in Normal and Tumor Cells

(2018) Teressa Paulsen et al.   TRENDS IN GENETICS

Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

(2018) Henrik Devitt Møller et al.   Nature Communications

Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity

(2017) Ciro Zanca et al.   GENES & DEVELOPMENT

MYC-containing amplicons in acute myeloid leukemia: Genomic structures, evolution, and transcriptional consequences

(2017) A ĹAbbate et al.   LEUKEMIA

Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation

(2017) Pankaj Kumar et al.   MOLECULAR CANCER RESEARCH

Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

(2017) Kristen M. Turner et al.   NATURE

Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens

(2017) Massa J. Shoura et al.   G3-Genes Genomes Genetics

Haplotyping germline and cancer genomes with high-throughput linked-read sequencing

(2016) Grace X Y Zheng et al.   NATURE BIOTECHNOLOGY

Clonal evolution of glioblastoma under therapy

(2016) Jiguang Wang et al.   NATURE GENETICS

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

Toward a Shared Vision for Cancer Genomic Data

(2016) Robert L. Grossman et al.   NEW ENGLAND JOURNAL OF MEDICINE

HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development

(2016) Susan J. Lindsay et al.   Frontiers in Neuroanatomy

Chromothripsis: A New Mechanism for Rapid Karyotype Evolution

(2015) Mitchell L. Leibowitz et al.   Annual Review of Genetics

An integrative framework for the identification of double minute chromosomes using next generation sequencing data

(2015) Matthew Hayes et al.   BMC GENETICS

CONSERTING: integrating copy-number analysis with structural-variation detection

(2015) Xiang Chen et al.   NATURE METHODS

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

(2014) Gang Wu et al.   NATURE GENETICS

Genomic organization and evolution of double minutes/homogeneously staining regions withMYCamplification in human cancer

(2014) Alberto L'Abbate et al.   NUCLEIC ACIDS RESEARCH

Phase II Trial of Erlotinib during and after Radiotherapy in Children with Newly Diagnosed High-Grade Gliomas

(2014) Ibrahim Qaddoumi et al.   Frontiers in Oncology

EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis

(2013) Krishna M. Talasila et al.   ACTA NEUROPATHOLOGICA

Double Minute Chromosomes in Glioblastoma Multiforme Are Revealed by Precise Reconstruction of Oncogenic Amplicons

(2013) J. Z. Sanborn et al.   CANCER RESEARCH

Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

(2013) David A. Nathanson et al.   SCIENCE

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Extrachromosomal MicroDNAs and Chromosomal Microdeletions in Normal Tissues

(2012) Y. Shibata et al.   SCIENCE

Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors

(2012) Igor Vivanco et al.   Cancer Discovery

Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format

(2011) M. N. Edmonson et al.   BIOINFORMATICS

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

Gene amplification as double minutes or homogeneously staining regions in solid tumors: Origin and structure

(2010) C. T. Storlazzi et al.   GENOME RESEARCH

Definition of Disease-Risk Stratification Groups in Childhood Medulloblastoma Using Combined Clinical, Pathologic, and Molecular Variables

(2010) David W. Ellison et al.   JOURNAL OF CLINICAL ONCOLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS