Genomic organization and evolution of double minutes/homogeneously staining regions withMYCamplification in human cancer

Cancer Cell Lines for Drug Discovery and Development

(2014) J. L. Wilding et al.   CANCER RESEARCH

Double Minute Chromosomes in Glioblastoma Multiforme Are Revealed by Precise Reconstruction of Oncogenic Amplicons

(2013) J. Z. Sanborn et al.   CANCER RESEARCH

Criteria for Inference of Chromothripsis in Cancer Genomes

(2013) Jan O. Korbel et al.   CELL

Genome-wide identification of genes with amplification and/or fusion in small cell lung cancer

(2013) Reika Iwakawa et al.   GENES CHROMOSOMES & CANCER

Expulsion of micronuclei containing amplified genes contributes to a decrease in double minute chromosomes from malignant tumor cells

(2013) Wei Ji et al.   INTERNATIONAL JOURNAL OF CANCER

Characterization at nucleotide resolution of the homogeneously staining region sites of insertion in two cancer cell lines

(2013) Anne Gibaud et al.   NUCLEIC ACIDS RESEARCH

Novel fusion transcripts in human gastric cancer revealed by transcriptome analysis

(2013) H-P Kim et al.   ONCOGENE

DELLY: structural variant discovery by integrated paired-end and split-read analysis

(2012) T. Rausch et al.   BIOINFORMATICS

Frequent PVT1 Rearrangement and Novel Chimeric Genes PVT1-NBEA and PVT1-WWOX Occur in Multiple Myeloma with 8q24 Abnormality

(2012) H. Nagoshi et al.   CANCER RESEARCH

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

(2012) Tobias Rausch et al.   CELL

The Phosphatase-Transcription Activator EYA1 Is Targeted by Anaphase-Promoting Complex/Cdh1 for Degradation at M-to-G1 Transition

(2012) J. Sun et al.   MOLECULAR AND CELLULAR BIOLOGY

Recombination-restarted replication makes inverted chromosome fusions at inverted repeats

(2012) Ken’Ichi Mizuno et al.   NATURE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

(2012) Paul A. Northcott et al.   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

A framework for identification of actionable cancer genome dependencies in small cell lung cancer

(2012) M. L. Sos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide screen identifies PVT1 as a regulator of Gemcitabine sensitivity in human pancreatic cancer cells

(2011) Lei You et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

(2011) Philip J. Stephens et al.   CELL

The FRA2C common fragile site maps to the borders of MYCN amplicons in neuroblastoma and is associated with gross chromosomal rearrangements in different cancers

(2011) Anne Blumrich et al.   HUMAN MOLECULAR GENETICS

MYC, TP53,and Chromosome 17 Copy-Number Alterations in Multiple Gastric Cancer Cell Lines and in Their Parental Primary Tumors

(2011) Mariana Ferreira Leal et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Regulation, Role, and Targeting of Akt in Cancer

(2011) Michael A. Davies   JOURNAL OF CLINICAL ONCOLOGY

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Discovery of recurrent t(6;7)(p25.3;q32.3) translocations in ALK-negative anaplastic large cell lymphomas by massively parallel genomic sequencing

(2010) A. L. Feldman et al.   BLOOD

Genome-wide mapping and assembly of structural variant breakpoints in the mouse genome

(2010) A. R. Quinlan et al.   GENOME RESEARCH

Gene amplification as double minutes or homogeneously staining regions in solid tumors: Origin and structure

(2010) C. T. Storlazzi et al.   GENOME RESEARCH

Extrachromosomal amplification mechanisms in a glioma with amplified sequences from multiple chromosome loci

(2010) Anne Gibaud et al.   HUMAN MOLECULAR GENETICS

A Small Molecule Inhibits Akt through Direct Binding to Akt and Preventing Akt Membrane Translocation

(2010) Donghwa Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mutation spectrum revealed by paired genome sequences from a lung cancer patient

(2010) William Lee et al.   NATURE

Amplification of a plasmid bearing a mammalian replication initiation region in chromosomal and extrachromosomal contexts

(2010) Seiyu Harada et al.   NUCLEIC ACIDS RESEARCH

Replication Stress Induces Genome-wide Copy Number Changes in Human Cells that Resemble Polymorphic and Pathogenic Variants

(2009) Martin F. Arlt et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A geometric approach for classification and comparison of structural variants

(2009) S. Sindi et al.   BIOINFORMATICS

Sample Type Bias in the Analysis of Cancer Genomes

(2009) D. A. Solomon et al.   CANCER RESEARCH

A small-cell lung cancer genome with complex signatures of tobacco exposure

(2009) Erin D. Pleasance et al.   NATURE

BreakDancer: an algorithm for high-resolution mapping of genomic structural variation

(2009) Ken Chen et al.   NATURE METHODS

A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation

(2009) P. J. Hastings et al.   PLoS Genetics

High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors; Four cases of homozygous deletions of the CDKN2A gene

(2008) Helena Caren et al.   BMC GENOMICS

Characterization of the Recurrent 8p11-12 Amplicon Identifies PPAPDC1B, a Phosphatase Protein, as a New Therapeutic Target in Breast Cancer

(2008) I. Bernard-Pierrot et al.   CANCER RESEARCH

Characterization of amplicons in neuroblastoma: High-resolution mapping using DNA microarrays, relationship with outcome, and identification of overexpressed genes

(2008) Anne Fix et al.   GENES CHROMOSOMES & CANCER

Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing

(2008) Peter J Campbell et al.   NATURE GENETICS