Silencing of microRNA-21in vivoameliorates autoimmune splenomegaly in lupus mice

Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression

(2011) E. Stagakis et al.   ANNALS OF THE RHEUMATIC DISEASES

MiR-34, SIRT1, and p53: The feedback loop

(2011) Munekazu Yamakuchi et al.   CELL CYCLE

The negative costimulatory molecule PD-1 modulates the balance between immunity and tolerance via miR-21

(2011) Dimitrios Iliopoulos et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1

(2010) Sha Zhao et al.   ARTHRITIS AND RHEUMATISM

MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer

(2010) Oskar W Rokhlin et al.   CANCER BIOLOGY & THERAPY

MicroRNA-21 Is a Downstream Effector of AKT That Mediates Its Antiapoptotic Effects via Suppression of Fas Ligand

(2010) Danish Sayed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

Knockdown of microRNA-21 Inhibits Proliferation and Increases Cell Death by Targeting Programmed Cell Death 4 (PDCD4) in Pancreatic Ductal Adenocarcinoma

(2010) Imran Bhatti et al.   JOURNAL OF GASTROINTESTINAL SURGERY

MicroRNA-21 and MicroRNA-148a Contribute to DNA Hypomethylation in Lupus CD4+ T Cells by Directly and Indirectly Targeting DNA Methyltransferase 1

(2010) W. Pan et al.   JOURNAL OF IMMUNOLOGY

Dicer Insufficiency and MicroRNA-155 Overexpression in Lupus Regulatory T Cells: An Apparent Paradox in the Setting of an Inflammatory Milieu

(2010) A. A. Divekar et al.   JOURNAL OF IMMUNOLOGY

Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma

(2010) Patricia P Reis et al.   Molecular Cancer

OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

(2010) Pedro P. Medina et al.   NATURE

T cells as therapeutic targets in SLE

(2010) José C. Crispín et al.   Nature Reviews Rheumatology

B cells as therapeutic targets in SLE

(2010) Iñaki Sanz et al.   Nature Reviews Rheumatology

Identification of Unique MicroRNA Signature Associated with Lupus Nephritis

(2010) Jeannie L. Te et al.   PLoS One

MicroRNA-146a contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins

(2009) Yuanjia Tang et al.   ARTHRITIS AND RHEUMATISM

The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation

(2009) Brigitte Lankat-Buttgereit et al.   BIOLOGY OF THE CELL

MicroRNA in the immune system, microRNA as an immune system

(2009) Li-Fan Lu et al.   IMMUNOLOGY

Lupus and T Cells

(2009) A La Cava   LUPUS

Negative regulation of TLR4 via targeting of the proinflammatory tumor suppressor PDCD4 by the microRNA miR-21

(2009) Frederick J Sheedy et al.   NATURE IMMUNOLOGY

Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

(2009) Jesper Worm et al.   NUCLEIC ACIDS RESEARCH

Altered B-cell signaling in lupus

(2008) Kui Liu et al.   AUTOIMMUNITY REVIEWS

Systemic IFN‐α drives kidney nephritis in B6.Sle123mice

(2008) Anna‐Marie Fairhurst et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS

MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene

(2008) Z Lu et al.   ONCOGENE