GM-CSF and uPA are required for Porphyromonas gingivalis -induced alveolar bone loss in a mouse periodontitis model

Activation of Urokinase Plasminogen Activator and Its Receptor Axis Is Essential for Macrophage Infiltration in a Prostate Cancer Mouse Model

(2015) Jian Zhang et al.   NEOPLASIA

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Characterization of T Cell Responses to the RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis in BALB/c Mice

(2014) V. Tam et al.   JOURNAL OF IMMUNOLOGY

Urokinase Plasminogen Activator Is a Central Regulator of Macrophage Three-Dimensional Invasion, Matrix Degradation, and Adhesion

(2014) A. J. Fleetwood et al.   JOURNAL OF IMMUNOLOGY

Macrophage Depletion AbatesPorphyromonas gingivalis–Induced Alveolar Bone Resorption in Mice

(2014) Roselind S. Lam et al.   JOURNAL OF IMMUNOLOGY

Induction of Bone Loss by Pathobiont-Mediated Nod1 Signaling in the Oral Cavity

(2013) Yizu Jiao et al.   Cell Host & Microbe

The plasminogen activation system: new targets in lung inflammation and remodeling

(2013) Michael Schuliga et al.   CURRENT OPINION IN PHARMACOLOGY

Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAPWorkshop on Periodontitis and Systemic Diseases

(2013) Maurizio S. Tonetti et al.   JOURNAL OF PERIODONTOLOGY

Periodontal systemic associations: review of the evidence

(2013) Gerard J. Linden et al.   JOURNAL OF PERIODONTOLOGY

Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis

(2012) Gerd R Burmester et al.   ANNALS OF THE RHEUMATIC DISEASES

Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy

(2012) L. van de Laar et al.   BLOOD

Plasminogen is a key proinflammatory regulator that accelerates the healing of acute and diabetic wounds

(2012) Y. Shen et al.   BLOOD

Differential Constitutive and Cytokine-Modulated Expression of Human Toll-like Receptors in Primary Neutrophils, Monocytes, and Macrophages

(2012) D. Shane O'Mahony et al.   International Journal of Medical Sciences

Porphyromonas gingivalis as a Potential Community Activist for Disease

(2012) R.P. Darveau et al.   JOURNAL OF DENTAL RESEARCH

Prevalence of Periodontitis in Adults in the United States: 2009 and 2010

(2012) P.I. Eke et al.   JOURNAL OF DENTAL RESEARCH

Macrophage-Specific TLR2 Signaling Mediates Pathogen-Induced TNF-Dependent Inflammatory Oral Bone Loss

(2012) G. Papadopoulos et al.   JOURNAL OF IMMUNOLOGY

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

GM-CSF Priming Drives Bone Marrow-Derived Macrophages to a Pro-Inflammatory Pattern and Downmodulates PGE2 in Response to TLR2 Ligands

(2012) Carlos Arterio Sorgi et al.   PLoS One

Temporal Changes in Cell Marker Expression and Cellular Infiltration in a Controlled Cortical Impact Model in Adult Male C57BL/6 Mice

(2012) Xuemei Jin et al.   PLoS One

Colony stimulating factors and myeloid cell biology in health and disease

(2012) John A. Hamilton et al.   TRENDS IN IMMUNOLOGY

Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

(2011) George Hajishengallis et al.   Cell Host & Microbe

Rheumatoid arthritis and periodontal disease

(2010) Jean-Marie Berthelot et al.   JOINT BONE SPINE

Oral Biofilm Architecture on Natural Teeth

(2010) Vincent Zijnge et al.   PLoS One

Urokinase-type plasminogen activator and arthritis progression: role in systemic disease with immune complex involvement

(2010) Andrew D Cook et al.   ARTHRITIS RESEARCH & THERAPY

The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases

(2009) John A. Hamilton et al.   ARTHRITIS AND RHEUMATISM

Regulation of cell signalling by uPAR

(2009) Harvey W. Smith et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Progression of chronic periodontitis can be predicted by the levels ofPorphyromonas gingivalisandTreponema denticolain subgingival plaque

(2009) S. J. Byrne et al.   Oral microbiology and immunology

Combined blockade of granulocyte-macrophage colony stimulating factor and interleukin 17 pathways potently suppresses chronic destructive arthritis in a tumour necrosis factor  -independent mouse model

(2008) C Plater-Zyberk et al.   ANNALS OF THE RHEUMATIC DISEASES

Porphyromonas gingivalis RgpA-Kgp Proteinase-Adhesin Complexes Penetrate Gingival Tissue and Induce Proinflammatory Cytokines or Apoptosis in a Concentration-Dependent Manner

(2008) N. M. O'Brien-Simpson et al.   INFECTION AND IMMUNITY