Diurnal Variation in P-glycoprotein-Mediated Transport and Cerebrospinal Fluid Turnover in the Brain

Chronopharmacology: New Insights and Therapeutic Implications

(2013) Robert Dallmann et al.   Annual Review of Pharmacology and Toxicology

Why Clinical Modulation of Efflux Transport at the Human Blood–Brain Barrier Is Unlikely: The ITC Evidence-Based Position

(2013) J C Kalvass et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The impact of P-gp functionality on non-steady state relationships between CSF and brain extracellular fluid

(2013) Joost Westerhout et al.   JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

Alteration in P-glycoprotein Functionality Affects Intrabrain Distribution of Quinidine More Than Brain Entry—A Study in Rats Subjected to Status Epilepticus by Kainate

(2012) Stina Syvänen et al.   AAPS Journal

Central and Peripheral Circadian Clocks in Mammals

(2012) Jennifer A. Mohawk et al.   Annual Review of Neuroscience

Circadian Variations in Exsorptive Transport: In Situ Intestinal Perfusion Data and In Vivo Relevance

(2012) Alper Okyar et al.   CHRONOBIOLOGY INTERNATIONAL

Pharmacokinetics of Single Ascending Doses of the P-Glycoprotein Inhibitor Tariquidar in Healthy Subjects

(2012) M. Bauer et al.   PHARMACOLOGY

Increased Risk of Antipsychotic-Related QT Prolongation During Nighttime

(2011) Junzo Watanabe et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

A Combined Experimental and Mathematical Approach for Molecular-based Optimization of Irinotecan Circadian Delivery

(2011) Annabelle Ballesta et al.   PLoS Computational Biology

Targeting pathophysiological rhythms: prednisone chronotherapy shows sustained efficacy in rheumatoid arthritis

(2010) F. Buttgereit et al.   ANNALS OF THE RHEUMATIC DISEASES

P-Glycoprotein Function at the Blood-Brain Barrier in Humans Can Be Quantified with the Substrate Radiotracer 11C-N-Desmethyl-Loperamide

(2010) W. C. Kreisl et al.   JOURNAL OF NUCLEAR MEDICINE

Influence of a Time-Restricted Feeding Schedule on the Daily Rhythm of abcb1a Gene Expression and Its Function in Rat Intestine

(2010) Y. Hayashi et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

A Pilot Study to Assess the Efficacy of Tariquidar to Inhibit P-glycoprotein at the Human Blood-Brain Barrier with (R)-11C-Verapamil and PET

(2009) C. C. Wagner et al.   JOURNAL OF NUCLEAR MEDICINE

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Targeting regulation of ABC efflux transporters in brain diseases: A novel therapeutic approach

(2009) Heidrun Potschka   PHARMACOLOGY & THERAPEUTICS

Circadian Clock-Controlled Intestinal Expression of the Multidrug-Resistance Gene mdr1a in Mice

(2008) Yuichi Murakami et al.   GASTROENTEROLOGY

Peripheral Nerve pericytes originating from the blood-nerve barrier expresses tight junctional molecules and transporters as barrier-forming cells

(2008) Fumitaka Shimizu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Diurnal Rhythmicity in the Transcription of Jejunal Drug Transporters

(2008) Adam T. Stearns et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Chronotherapy Improves Blood Pressure Control and Reverts the Nondipper Pattern in Patients With Resistant Hypertension

(2007) Ramón C. Hermida et al.   HYPERTENSION