Pharmacokinetics of Single Ascending Doses of the P-Glycoprotein Inhibitor Tariquidar in Healthy Subjects

Breast Cancer Resistance Protein and P-Glycoprotein in Brain Cancer: Two Gatekeepers Team Up

(2012) Sagar Agarwal et al.   CURRENT PHARMACEUTICAL DESIGN

Role of CNS efflux drug transporters in antiepileptic drug delivery: Overcoming CNS efflux drug transport

(2011) Heidrun Potschka   ADVANCED DRUG DELIVERY REVIEWS

Pgp-Mediated Interaction Between (R)-[11C]Verapamil and Tariquidar at the Human Blood–Brain Barrier: A Comparison With Rat Data

(2011) M Bauer et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Revisiting the ABCs of Multidrug Resistance in Cancer Chemotherapy

(2011) Amit K. Tiwari et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The “Specific” P-Glycoprotein Inhibitor Tariquidar Is Also a Substrate and an Inhibitor for Breast Cancer Resistance Protein (BCRP/ABCG2)

(2010) Pavitra Kannan et al.   ACS Chemical Neuroscience

Synthesis and evaluation of [11C]XR9576 to assess the function of drug efflux transporters using PET

(2010) Kazunori Kawamura et al.   ANNALS OF NUCLEAR MEDICINE

Synthesis and in vivo evaluation of [11C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor

(2010) Florian Bauer et al.   BIOORGANIC & MEDICINAL CHEMISTRY

P-Glycoprotein Function at the Blood-Brain Barrier in Humans Can Be Quantified with the Substrate Radiotracer 11C-N-Desmethyl-Loperamide

(2010) W. C. Kreisl et al.   JOURNAL OF NUCLEAR MEDICINE

Evaluation of Limiting Brain Penetration Related to P-glycoprotein and Breast Cancer Resistance Protein Using [11C]GF120918 by PET in Mice

(2010) Kazunori Kawamura et al.   MOLECULAR IMAGING AND BIOLOGY

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

Synthesis and Small-Animal Positron Emission Tomography Evaluation of [11C]-Elacridar As a Radiotracer to Assess the Distribution of P-Glycoprotein at the Blood−Brain Barrier

(2009) Bernd Dörner et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Pilot Study to Assess the Efficacy of Tariquidar to Inhibit P-glycoprotein at the Human Blood-Brain Barrier with (R)-11C-Verapamil and PET

(2009) C. C. Wagner et al.   JOURNAL OF NUCLEAR MEDICINE