HDAC4 preserves skeletal muscle structure following long-term denervation by mediating distinct cellular responses

Transcriptional Profile of Denervated Vastus Lateralis Muscle Derived from a Patient 8 Months after Spinal Cord Injury: A Case Report

(2017) R. Mancinelli et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis

(2016) Leslie M. Baehr et al.   Aging-US

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Antioxidant SkQ1 delays sarcopenia-associated damage of mitochondrial ultrastructure

(2016) Valeriya B. Vays et al.   Aging-US

Aerobic Exercise and Pharmacological Treatments Counteract Cachexia by Modulating Autophagy in Colon Cancer

(2016) Eva Pigna et al.   Scientific Reports

The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging

(2015) Michael E. Walsh et al.   AGING CELL

Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic

(2015) Emily K. Pugach et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Butyrate prevents muscle atrophy after sciatic nerve crush

(2015) Michael E. Walsh et al.   MUSCLE & NERVE

Muscle-specific E3 ubiquitin ligases are involved in muscle atrophy of cancer cachexia: An in vitro and in vivo study

(2015) LEI YUAN et al.   ONCOLOGY REPORTS

PGC-1α modulates denervation-induced mitophagy in skeletal muscle

(2015) Anna Vainshtein et al.   Skeletal Muscle

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

(2014) Wen-Xing Ding et al.   Autophagy

Switching on ubiquitylation by phosphorylating a ubiquitous activator

(2014) Gary S. Shaw   BIOCHEMICAL JOURNAL

DNA Methyltransferase 3a and Mitogen-activated Protein Kinase Signaling Regulate the Expression of Fibroblast Growth Factor-inducible 14 (Fn14) during Denervation-induced Skeletal Muscle Atrophy

(2014) Marjan M. Tajrishi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity

(2014) Lesley A. Kane et al.   JOURNAL OF CELL BIOLOGY

Motoneuron Loss Is Associated With Sarcopenia

(2014) Michael Drey et al.   Journal of the American Medical Directors Association

A novel crosstalk between two major protein degradation systems

(2013) Xiao J Wang et al.   Autophagy

Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression

(2013) Gaëlle Bruneteau et al.   BRAIN

Cardiac fibrosis in mice expressing an inducible myocardial-specific Cre driver

(2013) J. Lexow et al.   Disease Models & Mechanisms

Long-Term Supplementation With a Cystine-Based Antioxidant Delays Loss of Muscle Mass in Aging

(2013) I. Sinha-Hikim et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Denervation-induced mitochondrial dysfunction and autophagy in skeletal muscle of apoptosis-deficient animals

(2012) Michael F. N. O′Leary et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of Reactive Oxygen Species-Mediated Signaling in Aging

(2012) Vyacheslav M. Labunskyy et al.   ANTIOXIDANTS & REDOX SIGNALING

Upregulation of proteasome activity in muscle RING finger 1-null mice following denervation

(2012) Aldrin V. Gomes et al.   FASEB JOURNAL

Histone deacetylase inhibition suppresses myogenin-dependent atrogene activation in spinal muscular atrophy mice

(2012) Katherine V. Bricceno et al.   HUMAN MOLECULAR GENETICS

A Direct HDAC4-MAP Kinase Crosstalk Activates Muscle Atrophy Program

(2012) Moon-Chang Choi et al.   MOLECULAR CELL

Activation Kinetics and Off-Target Effects of Thymus-Initiated Cre Transgenes

(2012) Jianjun Shi et al.   PLoS One

Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice

(2012) V. Moresi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GABARAPL1 (GEC1): Original or copycat?

(2011) Jaclyn Nicole Le Grand et al.   Autophagy

The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice

(2011) Annabelle Z Caron et al.   BMC MUSCULOSKELETAL DISORDERS

Ubiquitin–proteasome pathway and cellular responses to oxidative stress

(2011) Fu Shang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Prevention of muscle disuse atrophy by MG132 proteasome inhibitor

(2011) Cecile Jamart et al.   MUSCLE & NERVE

Macroautophagy and ERK phosphorylation counteract the anti-proliferative effect of proteasome inhibitor in gastric cancer cells

(2010) William Ka Kei Wu et al.   Autophagy

Quantitation of "autophagic flux" in mature skeletal muscle

(2010) Jeong-Sun Ju et al.   Autophagy

Methylene Blue Reduces Aβ Levels and Rescues Early Cognitive Deficit by Increasing Proteasome Activity

(2010) David X. Medina et al.   BRAIN PATHOLOGY

Myogenin and Class II HDACs Control Neurogenic Muscle Atrophy by Inducing E3 Ubiquitin Ligases

(2010) Viviana Moresi et al.   CELL

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

(2010) Joo-Yong Lee et al.   EMBO JOURNAL

Autophagy in skeletal muscle

(2010) Marco Sandri   FEBS LETTERS

Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

(2010) Paolo Grumati et al.   NATURE MEDICINE

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction

(2009) G. S. Supinski et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Denervation-induced oxidative stress and autophagy signaling in muscle

(2009) Michael F.N. O’Leary et al.   Autophagy

The Role of ATF4 Stabilization and Autophagy in Resistance of Breast Cancer Cells Treated with Bortezomib

(2009) M. Milani et al.   CANCER RESEARCH

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreERT2

(2009) A. Y. Higashi et al.   JOURNAL OF IMMUNOLOGY

The emerging role of epigenetic modifications and chromatin remodeling in spinal muscular atrophy

(2009) Sebastian Lunke et al.   JOURNAL OF NEUROCHEMISTRY

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Skeletal Muscle Is a Primary Target of SOD1G93A-Mediated Toxicity

(2008) Gabriella Dobrowolny et al.   Cell Metabolism

Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease

(2008) N. Raben et al.   HUMAN MOLECULAR GENETICS

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes

(2008) E. Shvets et al.   JOURNAL OF CELL SCIENCE