Methylene Blue Reduces Aβ Levels and Rescues Early Cognitive Deficit by Increasing Proteasome Activity

Role of Mitochondria in Neurodegenerative Diseases: Mitochondria as a Therapeutic Target in Alzheimer's Disease

(2016) P. Hemachandra Reddy   CNS SPECTRUMS

Inhibition of Hsp70 by Methylene Blue Affects Signaling Protein Function and Ubiquitination and Modulates Polyglutamine Protein Degradation

(2010) Adrienne M. Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau

(2010) Antonella Caccamo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methylene blue fails to inhibit Tau and polyglutamine protein dependent toxicity in zebrafish

(2010) Frauke van Bebber et al.   NEUROBIOLOGY OF DISEASE

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models

(2009) Makiko Yamashita et al.   FEBS LETTERS

Rapamycin Rescues TDP-43 Mislocalization and the Associated Low Molecular Mass Neurofilament Instability

(2009) Antonella Caccamo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Manipulation of Hsp70 ATPase Activity Regulates Tau Stability

(2009) U. K. Jinwal et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ubiquitin-proteasome system in Alzheimer's disease

(2008) Salvatore Oddo   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Blocking A 42 Accumulation Delays the Onset and Progression of Tau Pathology via the C Terminus of Heat Shock Protein70-Interacting Protein: A Mechanistic Link between A  and Tau Pathology

(2008) S. Oddo et al.   JOURNAL OF NEUROSCIENCE

Hope in Alzheimer's fight emerges from unexpected places

(2008) Trisha Gura   NATURE MEDICINE

Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

(2008) S. Hauptmann et al.   NEUROBIOLOGY OF AGING

Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways

(2007) Hani Atamna et al.   FASEB JOURNAL

Aβ inhibits the proteasome and enhances amyloid and tau accumulation

(2007) Bertrand P. Tseng et al.   NEUROBIOLOGY OF AGING