Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model

Bidirectional Notch Signaling and Osteocyte-Derived Factors in the Bone Marrow Microenvironment Promote Tumor Cell Proliferation and Bone Destruction in Multiple Myeloma

(2016) J. Delgado-Calle et al.   CANCER RESEARCH

A novel 3D mesenchymal stem cell model of the multiple myeloma bone marrow niche: biologic and clinical applications

(2016) Jana Jakubikova et al.   Oncotarget

RhoB Mediates Phosphoantigen Recognition by Vγ9Vδ2 T Cell Receptor

(2016) Zsolt Sebestyen et al.   Cell Reports

3D tissue-engineered bone marrow as a novel model to study pathophysiology and drug resistance in multiple myeloma

(2015) Pilar de la Puente et al.   BIOMATERIALS

Promising therapies in multiple myeloma

(2015) G. Bianchi et al.   BLOOD

Pathogenesis beyond the cancer clone(s) in multiple myeloma

(2015) G. Bianchi et al.   BLOOD

Untouched GMP-Ready Purified Engineered Immune Cells to Treat Cancer

(2015) T. Straetemans et al.   CLINICAL CANCER RESEARCH

The osteoblastic niche in the context of multiple myeloma

(2014) Denise Toscani et al.   Annals of the New York Academy of Sciences

Investigating osteogenic differentiation in multiple myeloma using a novel 3D bone marrow niche model

(2014) M. R. Reagan et al.   BLOOD

Biomimetic Tissue-Engineered Systems for Advancing Cancer Research: NCI Strategic Workshop Report

(2014) T. K. Schuessler et al.   CANCER RESEARCH

Understanding the multiple biological aspects leading to myeloma

(2014) E. M. Boyle et al.   HAEMATOLOGICA

Bone marrow mesenchymal stem cell aspirates from alternative sources Is the knee as good as the iliac crest?

(2014) Javier Narbona-Carceles et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

The bone marrow niche for haematopoietic stem cells

(2014) Sean J. Morrison et al.   NATURE

Cancer Immunotherapy Using γδT Cells: Dealing with Diversity

(2014) Wouter Scheper et al.   Frontiers in Immunology

γδ T cells for cancer immunotherapy

(2014) Jonathan PH Fisher et al.   OncoImmunology

Preclinical models of multiple myeloma: a critical appraisal

(2013) Julia Schüler et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The Clinical Relevance of Cancer Cell Lines

(2013) J.-P. Gillet et al.   JNCI-Journal of the National Cancer Institute

γδT cells elicited by CMV reactivation after allo-SCT cross-recognize CMV and leukemia

(2013) W Scheper et al.   LEUKEMIA

Correction: Ex-Vivo Dynamic 3-D Culture of Human Tissues in the RCCS™ Bioreactor Allows the Study of Multiple Myeloma Biology and Response to Therapy

(2013) Marina Ferrarini et al.   PLoS One

Patient-Specific 3D Microfluidic Tissue Model for Multiple Myeloma

(2013) Wenting Zhang et al.   TISSUE ENGINEERING PART C-METHODS

Porous bioprinted constructs in BMP-2 non-viral gene therapy for bone tissue engineering

(2013) Loek D. Loozen et al.   Journal of Materials Chemistry B

 9 and  2CDR3 domains regulate functional avidity of T cells harboring  9 2TCRs

(2012) C. Grunder et al.   BLOOD

SNP-based mapping arrays reveal high genomic complexity in monoclonal gammopathies, from MGUS to myeloma status

(2012) L López-Corral et al.   LEUKEMIA

Tug of war in the haematopoietic stem cell niche: do myeloma plasma cells compete for the HSC niche?

(2012) J E Noll et al.   Blood Cancer Journal

Under one roof

(2012) Jayakumar R. Nair et al.   OncoImmunology

Redirecting   T cells against cancer cells by transfer of a broadly tumor-reactive   T-cell receptor

(2011) V. Marcu-Malina et al.   BLOOD

Multiple Myeloma Mesenchymal Stem Cells: Characterization, Origin, and Tumor-Promoting Effects

(2011) M. R. Reagan et al.   CLINICAL CANCER RESEARCH

Microenvironment: Neighbourhood watch

(2011) Virginia Hughes   NATURE

Distinct Tissue Formation by Heterogeneous Printing of Osteo- and Endothelial Progenitor Cells

(2011) Natalja E. Fedorovich et al.   TISSUE ENGINEERING PART A

Hypoxia Impedes Vasculogenesis of In Vitro Engineered Bone

(2011) Debby Gawlitta et al.   TISSUE ENGINEERING PART A

Myeloma cell-induced disruption of bone remodelling compartments leads to osteolytic lesions and generation of osteoclast-myeloma hybrid cells

(2009) Thomas L. Andersen et al.   BRITISH JOURNAL OF HAEMATOLOGY

A comparison of cytokine production in 2-dimensional and 3-dimensional cultures of bone marrow stromal cells of multiple myeloma patients in response to RPMI8226 myeloma cells.

(2009) Barbara Zdzisińska et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

Myeloma Bone Disease

(2009) Ralph D Sanderson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A unique three-dimensional model for evaluating the impact of therapy on multiple myeloma

(2008) J. Kirshner et al.   BLOOD

Pathogenesis of myeloma bone disease

(2008) G D Roodman   LEUKEMIA