Effects of MicroRNA on Regulatory T Cells and Implications for Adoptive Cellular Therapy to Ameliorate Graft-versus-Host Disease

Thymus-Derived Regulatory T Cell Development Is Regulated by C-Type Lectin-Mediated BIC/MicroRNA 155 Expression

(2017) Raquel Sánchez-Díaz et al.   MOLECULAR AND CELLULAR BIOLOGY

miR-146b antagomir-treated human Tregs acquire increased GVHD inhibitory potency

(2016) Y. Lu et al.   BLOOD

Transcriptome profiling of human FoxP3+ regulatory T cells

(2016) Ravikiran Bhairavabhotla et al.   HUMAN IMMUNOLOGY

MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor

(2016) Huang-Yu Yang et al.   IMMUNITY

miR-23∼27∼24 clusters control effector T cell differentiation and function

(2016) Sunglim Cho et al.   JOURNAL OF EXPERIMENTAL MEDICINE

miR-124a and miR-155 enhance differentiation of regulatory T cells in patients with neuropathic pain

(2016) Jens Heyn et al.   Journal of Neuroinflammation

Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment

(2016) Yohko Kitagawa et al.   NATURE IMMUNOLOGY

Umbilical cord blood-derived T regulatory cells to prevent GVHD: kinetics, toxicity profile, and clinical effect

(2015) C. G. Brunstein et al.   BLOOD

Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation

(2015) S. C. Warth et al.   EMBO JOURNAL

miRNA-regulated gene expression differs in celiac disease patients according to the age of presentation

(2015) Gaia Buoli Comani et al.   Genes and Nutrition

A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner

(2015) Li-Fan Lu et al.   IMMUNITY

MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTOR

(2015) Yogesh Singh et al.   JOURNAL OF IMMUNOLOGY

Prospects for Therapeutic Targeting of MicroRNAs in Human Immunological Diseases

(2015) Marisa E. Luck et al.   JOURNAL OF IMMUNOLOGY

Altered expression and editing of miRNA-100 regulates iTreg differentiation

(2015) Vinny Negi et al.   NUCLEIC ACIDS RESEARCH

Type 1 diabetes immunotherapy using polyclonal regulatory T cells

(2015) Jeffrey A. Bluestone et al.   Science Translational Medicine

Clinical relevance of miR-mediated HLA-G regulation and the associated immune cell infiltration in renal cell carcinoma

(2015) Simon Jasinski-Bergner et al.   OncoImmunology

miRNA-regulated gene expression differs in celiac disease patients according to the age of presentation

(2015) Gaia Buoli Comani et al.   Genes and Nutrition

FOXP3 is a direct target of miR15a/16 in umbilical cord blood regulatory T cells

(2014) X Liu et al.   BONE MARROW TRANSPLANTATION

MicroRNA-Containing T-Regulatory-Cell-Derived Exosomes Suppress Pathogenic T Helper 1 Cells

(2014) Isobel S. Okoye et al.   IMMUNITY

miR-17-92 Cluster Targets Phosphatase and Tensin Homology and Ikaros Family Zinc Finger 4 to Promote TH17-mediated Inflammation

(2014) Si-Qi Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreased expression of microRNA-21 correlates with the imbalance of Th17 and Treg cells in patients with rheumatoid arthritis

(2014) Liyang Dong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MicroRNA networks in regulatory T cells

(2014) Xuehua Tang et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial

(2014) Glen A Kennedy et al.   LANCET ONCOLOGY

The miR-17∼92a Cluster of MicroRNAs Is Required for the Fitness of Foxp3+ Regulatory T Cells

(2014) Jarrod P. J. Skinner et al.   PLoS One

Serum microRNAs as Biomarkers of Human Lymphocyte Activation in Health and Disease

(2014) Paola de Candia et al.   Frontiers in Immunology

Essentials of Th17 cell commitment and plasticity

(2013) P. Muranski et al.   BLOOD

Targeted Delivery of microRNA-29b by Transferrin-Conjugated Anionic Lipopolyplex Nanoparticles: A Novel Therapeutic Strategy in Acute Myeloid Leukemia

(2013) X. Huang et al.   CLINICAL CANCER RESEARCH

MicroRNA regulation of T-cell development

(2013) James Dooley et al.   IMMUNOLOGICAL REVIEWS

MicroRNA-126 regulates the induction and function of CD4+Foxp3+regulatory T cells through PI3K/AKT pathway

(2013) Andong Qin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

microRNA-17-92 Regulates IL-10 Production by Regulatory T Cells and Control of Experimental Autoimmune Encephalomyelitis

(2013) D. de Kouchkovsky et al.   JOURNAL OF IMMUNOLOGY

MicroRNAs of the miR-17∼92 family are critical regulators of TFH differentiation

(2013) Seung Goo Kang et al.   NATURE IMMUNOLOGY

MicroRNAs in T helper cell differentiation and plasticity

(2013) Silvia Monticelli   SEMINARS IN IMMUNOLOGY

miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Schistosome and Leishmania-associated Inflammation

(2013) Samir Kelada et al.   PLoS Pathogens

Regulation of acute graft-versus-host disease by microRNA-155

(2012) P. Ranganathan et al.   BLOOD

MicroRNA let-7e is associated with the pathogenesis of experimental autoimmune encephalomyelitis

(2012) Hongbing Guan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MicroRNA Profile of Circulating CD4-positive Regulatory T Cells in Human Adults and Impact of Differentially Expressed MicroRNAs on Expression of Two Genes Essential to Their Function

(2012) Hussein Fayyad-Kazan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA 10a Marks Regulatory T Cells

(2012) Lukas T. Jeker et al.   PLoS One

MicroRNA-155 Modulates Treg and Th17 Cells Differentiation and Th17 Cell Function by Targeting SOCS1

(2012) Rui Yao et al.   PLoS One

Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation

(2011) S. Jiang et al.   BLOOD

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

MicroRNA control of lymphocyte differentiation and function

(2011) Laura Belver et al.   CURRENT OPINION IN IMMUNOLOGY

Molecular mechanisms underlying the regulation and functional plasticity of FOXP3+ regulatory T cells

(2011) Y Gao et al.   GENES AND IMMUNITY

Silencing MicroRNA-155 Ameliorates Experimental Autoimmune Encephalomyelitis

(2011) G. Murugaiyan et al.   JOURNAL OF IMMUNOLOGY

MicroRNA-155 may affect allograft survival by regulating the expression of suppressor of cytokine signaling 1

(2011) Maomao Zhang et al.   MEDICAL HYPOTHESES

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

(2011) Marc Beyer et al.   NATURE IMMUNOLOGY

MicroRNAs: Potential biomarker in organ transplantation

(2011) Juan Shan et al.   TRANSPLANT IMMUNOLOGY

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors: Figure 1.

(2010) Matthias Merkenschlager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients

(2009) Renata Hezova et al.   CELLULAR IMMUNOLOGY

Human natural Treg microRNA signature: Role of microRNA‐31 and microRNA‐21 in FOXP3 expression

(2009) Redouane Rouas et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

(2009) James L. Riley et al.   IMMUNITY

Natural and Adaptive Foxp3+ Regulatory T Cells: More of the Same or a Division of Labor?

(2009) Maria A. Curotto de Lafaille et al.   IMMUNITY

Foxp3-Dependent MicroRNA155 Confers Competitive Fitness to Regulatory T Cells by Targeting SOCS1 Protein

(2009) Li-Fan Lu et al.   IMMUNITY

MicroRNAs and immune regulatory T cells

(2009) Li Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cutting Edge: The Foxp3 Target miR-155 Contributes to the Development of Regulatory T Cells

(2009) S. Kohlhaas et al.   JOURNAL OF IMMUNOLOGY

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

miR-155 Inhibition Sensitizes CD4+ Th Cells for TREG Mediated Suppression

(2009) Heiko F. Stahl et al.   PLoS One

Tie2cre-induced inactivation of the miRNA-processing enzyme Dicer disrupts invariant NKT cell development

(2009) L. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T-Cells Protect From Type 1 Diabetes After Induction by Coxsackievirus Infection in the Context of Transforming Growth Factor- 

(2008) M. J. Richer et al.   DIABETES

miR-142-3p restricts cAMP production in CD4+CD25− T cells and CD4+CD25+ TREG cells by targeting AC9 mRNA

(2008) Bo Huang et al.   EMBO REPORTS

T Regulatory Cells in Autoimmune Diabetes: Past Challenges, Future Prospects

(2008) Jeffrey A. Bluestone et al.   JOURNAL OF CLINICAL IMMUNOLOGY

The RNAseIII enzyme Drosha is critical in T cells for preventing lethal inflammatory disease

(2008) Mark M.W. Chong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dicer-dependent microRNA pathway safeguards regulatory T cell function

(2008) Adrian Liston et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

(2008) Changchun Xiao et al.   NATURE IMMUNOLOGY