Vasa Vasorum Angiogenesis: Key Player in the Initiation and Progression of Atherosclerosis and Potential Target for the Treatment of Cardiovascular Disease

Relationship of C-reactive protein reduction to cardiovascular event reduction following treatment with canakinumab: a secondary analysis from the CANTOS randomised controlled trial

(2018) Paul M Ridker et al.   LANCET

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Central Role of Metabolism in Endothelial Cell Function and Vascular Disease

(2017) Laura Bierhansl et al.   PHYSIOLOGY

Targeting vasa vasorum dysfunction to prevent atherosclerosis

(2017) Erin C. Boyle et al.   VASCULAR PHARMACOLOGY

Targeting endothelial metabolism for anti-angiogenesis therapy: A pharmacological perspective

(2017) Rindert Missiaen et al.   VASCULAR PHARMACOLOGY

Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8

(2016) Johanna P. Laakkonen et al.   ANGIOGENESIS

Bromodomains: Structure, function and pharmacology of inhibition

(2016) Elena Ferri et al.   BIOCHEMICAL PHARMACOLOGY

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

(2016) Anna Rita Cantelmo et al.   CANCER CELL

The multifactorial nature of microRNAs in vascular remodelling

(2016) S.M.J. Welten et al.   CARDIOVASCULAR RESEARCH

Chronic adventitial inflammation, vasa vasorum expansion, and 5-lipoxygenase up-regulation in irradiated arteries from cancer survivors

(2016) Martin Halle et al.   FASEB JOURNAL

Pericytes in diabetes-associated vascular disease

(2016) Nele Warmke et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Anti-vascular endothelial growth factor treatment induces blood flow recovery through vascular remodeling in high-fat diet induced diabetic mice

(2016) Lamei Xiao et al.   MICROVASCULAR RESEARCH

The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer

(2016) L L da Motta et al.   ONCOGENE

Cellular Model of Atherogenesis Based on Pluripotent Vascular Wall Pericytes

(2016) Ekaterina A. Ivanova et al.   Stem Cells International

Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice

(2015) Thomas L. Theelen et al.   ATHEROSCLEROSIS

Inflammation and Immunity in Diseases of the Arterial Tree: Players and Layers

(2015) P. Libby et al.   CIRCULATION RESEARCH

Angiogenesis Inhibitor, Endostar, Prevents Vasa Vasorum Neovascularization in a Swine Atherosclerosis Model

(2015) Xiaoming Xu et al.   Journal of Atherosclerosis and Thrombosis

Human miR-221/222 in Physiological and Atherosclerotic Vascular Remodeling

(2015) Dmitry A. Chistiakov et al.   Biomed Research International

Inhibition of miR-92a improves re-endothelialization and prevents neointima formation following vascular injury

(2014) J.-M. Daniel et al.   CARDIOVASCULAR RESEARCH

Vasa Vasorum in Normal and Diseased Arteries

(2014) Mary Jo Mulligan-Kehoe et al.   CIRCULATION

DNA Methylation Map of Human Atherosclerosis

(2014) S. Zaina et al.   Circulation-Cardiovascular Genetics

Elastin fragmentation in atherosclerotic mice leads to intraplaque neovascularization, plaque rupture, myocardial infarction, stroke, and sudden death

(2014) Carole Van der Donckt et al.   EUROPEAN HEART JOURNAL

Thalidomide influences atherogenesis in aortas of ApoE−/−/LDLR−/− double knockout mice: a nano-CT study

(2014) Marian Kampschulte et al.   INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING

MicroRNAs in Atherosclerosis

(2014) Ali A. Hosin et al.   JOURNAL OF VASCULAR RESEARCH

NF-κB Directs Dynamic Super Enhancer Formation in Inflammation and Atherogenesis

(2014) Jonathan D. Brown et al.   MOLECULAR CELL

A role for pericytes in coronary no-reflow

(2014) Fergus M. O'Farrell et al.   Nature Reviews Cardiology

Histone and DNA Methylation–Mediated Epigenetic Downregulation of Endothelial Kruppel-Like Factor 2 by Low-Density Lipoprotein Cholesterol

(2013) Ajay Kumar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hyperglycaemia is associated with impaired vasa vasorum neovascularization and accelerated atherosclerosis in apolipoprotein-E deficient mice

(2013) K.J. Veerman et al.   ATHEROSCLEROSIS

Cardiovascular disease in autoimmune rheumatic diseases

(2013) Ivana Hollan et al.   AUTOIMMUNITY REVIEWS

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Incomplete and transitory decrease of glycolysis

(2013) Sandra Schoors et al.   CELL CYCLE

Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis

(2013) Sandra Schoors et al.   Cell Metabolism

Pathophysiology of Atherosclerosis Plaque Progression

(2013) Kenichi Sakakura et al.   Heart Lung and Circulation

LOX-1, OxLDL, and Atherosclerosis

(2013) Angela Pirillo et al.   MEDIATORS OF INFLAMMATION

Familial Hypercholesterolemia and Atherosclerosis in Cloned Minipigs Created by DNA Transposition of a Human PCSK9 Gain-of-Function Mutant

(2013) R. H. Al-Mashhadi et al.   Science Translational Medicine

Macrophages Transmit Potent Proangiogenic Effects of oxLDL In Vitro and In Vivo Involving HIF-1α Activation: a Novel Aspect of Angiogenesis in Atherosclerosis

(2013) Randolph Hutter et al.   Journal of Cardiovascular Translational Research

Porcine Models of Accelerated Coronary Atherosclerosis: Role of Diabetes Mellitus and Hypercholesterolemia

(2013) Damir Hamamdzic et al.   Journal of Diabetes Research

Genotype-Dependent Impairment of Hemoglobin Clearance Increases Oxidative and Inflammatory Response in Human Diabetic Atherosclerosis

(2012) Meerarani Purushothaman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Fibroblast Growth Factor-2 Is Required for Vasa Vasorum Plexus Stability in Hypercholesterolemic Mice

(2012) Jessica I. Mollmark et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MEDI3617, a human anti-Angiopoietin 2 monoclonal antibody, inhibits angiogenesis and tumor growth in human tumor xenograft models

(2012) Ching Leow   INTERNATIONAL JOURNAL OF ONCOLOGY

Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell–Cell Junctions and Lung Metastasis

(2012) Tanja Holopainen et al.   JNCI-Journal of the National Cancer Institute

Plaque Rupture Complications in Murine Atherosclerotic Vein Grafts Can Be Prevented by TIMP-1 Overexpression

(2012) Margreet R. de Vries et al.   PLoS One

Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs

(2012) C. Voellenkle et al.   RNA

Augmented angiogenesis in adventitia promotes growth of atherosclerotic plaque in apolipoprotein E-deficient mice

(2011) Kimie Tanaka et al.   ATHEROSCLEROSIS

Antiangiogenic Activity of rPAI-1 23 Promotes Vasa Vasorum Regression in Hypercholesterolemic Mice Through a Plasmin-Dependent Mechanism

(2011) Jessica Mollmark et al.   CIRCULATION RESEARCH

Normalization of the Vasculature for Treatment of Cancer and Other Diseases

(2011) Shom Goel et al.   PHYSIOLOGICAL REVIEWS

Animal models for the atherosclerosis research: a review

(2011) Li Xiangdong et al.   Protein & Cell

Red Cells, Hemoglobin, Heme, Iron, and Atherogenesis

(2010) Emőke Nagy et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Quantitative CT imaging of the spatio-temporal distribution patterns of vasa vasorum in aortas of apoE−/−/LDL−/− double knockout mice

(2010) M. Kampschulte et al.   ATHEROSCLEROSIS

Extracellular matrix, inflammation, and the angiogenic response

(2010) A. G. Arroyo et al.   CARDIOVASCULAR RESEARCH

Composition of Carotid Atherosclerotic Plaque Is Associated With Cardiovascular Outcome

(2010) Willem E. Hellings et al.   CIRCULATION

Human Adult Vena Saphena Contains Perivascular Progenitor Cells Endowed With Clonogenic and Proangiogenic Potential

(2010) Paola Campagnolo et al.   CIRCULATION

Atherosclerotic lesions in mouse and man: is it the same disease?

(2010) Jacob Fog Bentzon et al.   CURRENT OPINION IN LIPIDOLOGY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Contrast-Enhanced Ultrasound Imaging Detects Intraplaque Neovascularization in an Experimental Model of Atherosclerosis

(2010) Chiara Giannarelli et al.   JACC-Cardiovascular Imaging

The vasa vasorum in diseased and nondiseased arteries

(2009) Mary Jo Mulligan-Kehoe   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mechanisms of Vessel Branching

(2009) Frederik De Smet et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Prevention of vasa vasorum neovascularization attenuates early neointima formation in experimental hypercholesterolemia

(2009) Mario Gössl et al.   BASIC RESEARCH IN CARDIOLOGY

Impaired Fibrillin-1 Function Promotes Features of Plaque Instability in Apolipoprotein E–Deficient Mice

(2009) Jozef L. Van Herck et al.   CIRCULATION

The Antiangiogenic Activity of rPAI-1 23 Inhibits Vasa Vasorum and Growth of Atherosclerotic Plaque

(2009) Mary Drinane et al.   CIRCULATION RESEARCH

A Necessary Role of miR-221 and miR-222 in Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia

(2009) Xiaojun Liu et al.   CIRCULATION RESEARCH

On the Sympathetic Innervation of the Human Greater Saphenous Vein: Relevance to Clinical Practice

(2009) Andrzej Loesch et al.   Current Vascular Pharmacology

Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of agedApoE−/−mice

(2009) Rolf Gräbner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thin-Walled Microvessels in Human Coronary Atherosclerotic Plaques Show Incomplete Endothelial Junctions

(2009) Judith C. Sluimer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Adventitia: the vital wall of conduit arteries

(2009) Marie Gingras et al.   Journal of the American Society of Hypertension

A Role for a CXCR2/Phosphatidylinositol 3-Kinase   Signaling Axis in Acute and Chronic Vascular Permeability

(2009) J. Gavard et al.   MOLECULAR AND CELLULAR BIOLOGY

MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

(2009) A. Bonauer et al.   SCIENCE

Antiangiogenic Treatment Prevents Adventitial Constrictive Remodeling in Graft Arteriosclerosis

(2009) Olivier Thaunat et al.   TRANSPLANTATION

Imaging angiogenesis and the microenvironment 

(2008) DAI FUKUMURA et al.   APMIS

Turn me on: regulating HIF transcriptional activity

(2008) K Lisy et al.   CELL DEATH AND DIFFERENTIATION

Tumor Escape from Endogenous, Extracellular Matrix-Associated Angiogenesis Inhibitors by Up-Regulation of Multiple Proangiogenic Factors

(2008) N. T. Fernando et al.   CLINICAL CANCER RESEARCH

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

Control of atherosclerotic plaque vulnerability: Insights from transgenic mice

(2008) Sylvia Heeneman   Frontiers in Bioscience-Landmark

Antagomir-mediated silencing of endothelial cell specific microRNA-126 impairs ischemia-induced angiogenesis

(2008) Coen van Solingen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Balance between Angiopoietin-1 and Angiopoietin-2 Is in Favor of Angiopoietin-2 in Atherosclerotic Plaques with High Microvessel Density

(2008) Simone Post et al.   JOURNAL OF VASCULAR RESEARCH

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1

(2008) T. A. Harris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA