High Complement Factor H-Related (FHR)-3 Levels Are Associated With the Atypical Hemolytic-Uremic Syndrome-Risk Allele CFHR3*B

Circulating complement factor H–related proteins 1 and 5 correlate with disease activity in IgA nephropathy

(2017) Nicholas R. Medjeral-Thomas et al.   KIDNEY INTERNATIONAL

Elevated factor H–related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy

(2017) Agustín Tortajada et al.   KIDNEY INTERNATIONAL

Self-nonself discrimination by the complement system

(2016) Seppo Meri   FEBS LETTERS

Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases

(2016) Nicole Schäfer et al.   Frontiers in Immunology

Complement Factor H-Related Protein 3 Serum Levels Are Low Compared to Factor H and Mainly Determined by Gene Copy Number Variation in CFHR3

(2016) Richard B. Pouw et al.   PLoS One

A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome

(2015) R. C. Challis et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome

(2015) Maria E. Bernabéu-Herrero et al.   MOLECULAR IMMUNOLOGY

Factor H-related proteins determine complement-activating surfaces

(2015) Mihály Józsi et al.   TRENDS IN IMMUNOLOGY

Factors determining penetrance in familial atypical haemolytic uraemic syndrome

(2014) Francis H Sansbury et al.   JOURNAL OF MEDICAL GENETICS

Cardiovascular complications in atypical haemolytic uraemic syndrome

(2014) Marina Noris et al.   Nature Reviews Nephrology

Genetics of Atypical Hemolytic Uremic Syndrome (aHUS)

(2014) Marta Hidalgo et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Complement Genes Strongly Predict Recurrence and Graft Outcome in Adult Renal Transplant Recipients with Atypical Hemolytic and Uremic Syndrome

(2013) M. Le Quintrec et al.   AMERICAN JOURNAL OF TRANSPLANTATION

C3 glomerulopathy–associated CFHR1 mutation alters FHR oligomerization and complement regulation

(2013) Agustín Tortajada et al.   JOURNAL OF CLINICAL INVESTIGATION

Combined Complement Gene Mutations in Atypical Hemolytic Uremic Syndrome Influence Clinical Phenotype

(2013) E. Bresin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Complement factor H related proteins (CFHRs)

(2013) Christine Skerka et al.   MOLECULAR IMMUNOLOGY

Atypical Hemolytic Uremic Syndrome

(2013) David Kavanagh et al.   SEMINARS IN NEPHROLOGY

A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome

(2011) N. J. Francis et al.   BLOOD

Factor H and CFHR1 polymorphisms associated with atypical Haemolytic Uraemic Syndrome (aHUS) are differently expressed in Tunisian and in Caucasian populations

(2011) N. Leban et al.   International Journal of Immunogenetics

Genome-wide association study identifies susceptibility loci for IgA nephropathy

(2011) Ali G Gharavi et al.   NATURE GENETICS

Advances in understanding the aetiology of atypical Haemolytic Uraemic Syndrome

(2010) Pilar Sánchez-Corral et al.   BRITISH JOURNAL OF HAEMATOLOGY

An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

(2010) Lars G. Fritsche et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease

(2010) Sonia Davila et al.   NATURE GENETICS

Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome

(2009) C. Abarrategui-Garrido et al.   BLOOD

The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome

(2009) M-A Dragon-Durey et al.   JOURNAL OF MEDICAL GENETICS

Atypical Hemolytic–Uremic Syndrome

(2009) Marina Noris et al.   NEW ENGLAND JOURNAL OF MEDICINE