Impact of Cigarette Smoking on the Gastrointestinal Tract Inflammation: Opposing Effects in Crohn’s Disease and Ulcerative Colitis

Cigarette Smoking Triggers Colitis by IFN-γ+ CD4+ T Cells

(2017) Gihyun Lee et al.   Frontiers in Immunology

Three components of cigarette smoke altered the growth and apoptosis of metastatic colon cancer cells via inducing the synthesis of reactive oxygen species and endoplasmic reticulum stress

(2016) Hae-Miru Lee et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Infiltration of IL-17-Producing T Cells and Treg Cells in a Mouse Model of Smoke-Induced Emphysema

(2016) Min-Chao Duan et al.   INFLAMMATION

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

(2016) Isabelle Cleynen et al.   LANCET

Transient Receptor Potential Channels in Intestinal Inflammation: What Is the Impact of Cigarette Smoking?

(2016) Liesbeth Allais et al.   PATHOBIOLOGY

Chronic cigarette smoke exposure induces microbial and inflammatory shifts and mucin changes in the murine gut

(2015) Liesbeth Allais et al.   ENVIRONMENTAL MICROBIOLOGY

Failure of interleukin 13 blockade in ulcerative colitis

(2015) Herbert Tilg et al.   GUT

Increased oxidative stress and disrupted small intestinal tight junctions in cigarette smoke-exposed rats

(2015) HONGWEI LI et al.   Molecular Medicine Reports

Longer and safer gastric residence

(2015) Vitaliy V. Khutoryanskiy   NATURE MATERIALS

Immunopathogenesis of IBD: current state of the art

(2015) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

Cigarette Smoking Impairs Human Pulmonary Immunity toMycobacterium tuberculosis

(2014) Seónadh M. O’Leary et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Genetic studies of Crohn's disease: Past, present and future

(2014) Jimmy Z. Liu et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Heme Oxygenase-1 as a Target for the Design of Gene and Pharmaceutical Therapies for Autoimmune Diseases

(2014) Juan Mackern-Oberti et al.   CURRENT GENE THERAPY

IL-13Rα2-bearing, type II NKT cells reactive to sulfatide self-antigen populate the mucosa of ulcerative colitis

(2014) Ivan J Fuss et al.   GUT

Opposing Effects of Smoking in Ulcerative Colitis and Crohnʼs Disease May Be Explained by Differential Effects on Dendritic Cells

(2014) Aito Ueno et al.   INFLAMMATORY BOWEL DISEASES

Smoking Cessation Alters Intestinal Microbiota

(2014) Luc Biedermann et al.   INFLAMMATORY BOWEL DISEASES

Cigarette smoking and gastrointestinal diseases: The causal relationship and underlying molecular mechanisms (Review)

(2014) L.F. LI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Cigarette smoking is associated with intestinal barrier dysfunction in the small intestine but not in the large intestine of mice

(2014) Lugen Zuo et al.   Journal of Crohns & Colitis

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress

(2013) Eveline Hoefkens et al.   Autophagy

Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohn's disease

(2013) J Jasper Deuring et al.   GUT

Paneth cells as a site of origin for intestinal inflammation

(2013) Timon E. Adolph et al.   NATURE

The biology behind the atherothrombotic effects of cigarette smoke

(2013) Adam Csordas et al.   Nature Reviews Cardiology

Distinct Profiles of Effector Cytokines Mark the Different Phases of Crohn’s Disease

(2013) Francesca Zorzi et al.   PLoS One

Continuous and Discontinuous Cigarette Smoke Exposure Differentially Affects Protective Th1 Immunity against Pulmonary Tuberculosis

(2013) Christopher R. Shaler et al.   PLoS One

Review article: ulcerative colitis, smoking and nicotine therapy

(2012) P. C. Lunney et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Effects of Cigarette Smoke and its Active Components on Ulcer Formation and Healing in the Gastrointestinal Mucosa

(2012) L. Zhang et al.   CURRENT MEDICINAL CHEMISTRY

Comparative study of the main characteristics and composition of the mainstream smoke of ten cigarette brands sold in Spain

(2012) A. Marcilla et al.   FOOD AND CHEMICAL TOXICOLOGY

Ulcerative colitis

(2012) Ingrid Ordás et al.   LANCET

Crohn's disease

(2012) Daniel C Baumgart et al.   LANCET

Aryl Hydrocarbon Receptor-Induced Signals Up-regulate IL-22 Production and Inhibit Inflammation in the Gastrointestinal Tract

(2011) Ivan Monteleone et al.   GASTROENTEROLOGY

Epidemiology and Natural History of Inflammatory Bowel Diseases

(2011) Jacques Cosnes et al.   GASTROENTEROLOGY

Crohn's disease: NOD2, autophagy and ER stress converge

(2011) T. Fritz et al.   GUT

Smokers with active Crohnʼs disease have a clinically relevant dysbiosis of the gastrointestinal microbiota*

(2011) Jane L. Benjamin et al.   INFLAMMATORY BOWEL DISEASES

An Anti-Inflammatory Role for Carbon Monoxide and Heme Oxygenase-1 in Chronic Th2-Mediated Murine Colitis

(2011) S. Z. Sheikh et al.   JOURNAL OF IMMUNOLOGY

Anti-inflammatory effects of nicotine in obesity and ulcerative colitis

(2011) Shaheen E Lakhan et al.   Journal of Translational Medicine

Cigarette smoking alters epithelial apoptosis and immune composition in murine GALT

(2011) Stephanie Verschuere et al.   LABORATORY INVESTIGATION

New insights into the immunology of chronic obstructive pulmonary disease

(2011) Guy G Brusselle et al.   LANCET

Correction: The role of bacteria and pattern-recognition receptors in Crohn's disease

(2011) Si Ming Man et al.   Nature Reviews Gastroenterology & Hepatology

A Pyrosequencing Study in Twins Shows That Gastrointestinal Microbial Profiles Vary With Inflammatory Bowel Disease Phenotypes

(2010) Ben P. Willing et al.   GASTROENTEROLOGY

Worldwide burden of disease from exposure to second-hand smoke: a retrospective analysis of data from 192 countries

(2010) Mattias Öberg et al.   LANCET

Nod2 is required for the regulation of commensal microbiota in the intestine

(2009) T. Petnicki-Ocwieja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IKKα Causes Chromatin Modification on Pro-Inflammatory Genes by Cigarette Smoke in Mouse Lung

(2008) Se-Ran Yang et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Oxidative Stress, Inflammation and Neutrophil Superoxide Release in Patients with Crohn’s Disease: Distinction Between Active and Non-active Disease

(2008) Irit Maor et al.   DIGESTIVE DISEASES AND SCIENCES

Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases

(2008) C. N Bernstein et al.   GUT

What is the link between the use of tobacco and IBD?

(2008) Jacques Cosnes   INFLAMMATORY BOWEL DISEASES

Epithelial apoptosis is a prominent feature of the epithelial barrier disturbance in intestinal inflammation: effect of pro-inflammatory interleukin-13 on epithelial cell function

(2008) F Heller et al.   Mucosal Immunology

The role of IL-13 and NK T cells in experimental and human ulcerative colitis

(2008) I J Fuss et al.   Mucosal Immunology

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE