The Activin A-Peroxisome Proliferator-Activated Receptor Gamma Axis Contributes to the Transcriptome of GM-CSF-Conditioned Human Macrophages

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

(2017) Alexander V. Misharin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease

(2016) Juan Carlos Corona et al.   FREE RADICAL BIOLOGY AND MEDICINE

GM-CSF: From Growth Factor to Central Mediator of Tissue Inflammation

(2016) Burkhard Becher et al.   IMMUNITY

Atypical Activin A and IL-10 Production Impairs Human CD16+Monocyte Differentiation into Anti-Inflammatory Macrophages

(2016) Érika González-Domínguez et al.   JOURNAL OF IMMUNOLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

PPARgene: A Database of Experimentally Verified and Computationally Predicted PPAR Target Genes

(2016) Li Fang et al.   PPAR Research

CD163L1 and CLEC5A discriminate subsets of human resident and inflammatory macrophages in vivo

(2015) E. Gonzalez-Dominguez et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Targeting GM-CSF in inflammatory diseases

(2015) Ian P. Wicks et al.   Nature Reviews Rheumatology

A transcriptional perspective on human macrophage biology

(2015) Joachim L. Schultze et al.   SEMINARS IN IMMUNOLOGY

Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages

(2014) Mario Kratz et al.   Cell Metabolism

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Peroxisome Proliferator-Activated Receptor-  Regulates the Expression of Alveolar Macrophage Macrophage Colony-Stimulating Factor

(2014) T. L. Bonfield et al.   JOURNAL OF IMMUNOLOGY

Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile

(2014) Blanca Soler Palacios et al.   JOURNAL OF PATHOLOGY

Fate PPAR-titioning: PPAR-γ 'instructs' alveolar macrophage development

(2014) Florent Ginhoux   NATURE IMMUNOLOGY

Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages

(2014) Christoph Schneider et al.   NATURE IMMUNOLOGY

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

The role of lipid-activated nuclear receptors in shaping macrophage and dendritic cell function: From physiology to pathology

(2013) Mate Kiss et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Defining GM-CSF- and Macrophage-CSF-Dependent Macrophage Responses by In Vitro Models

(2012) D. C. Lacey et al.   JOURNAL OF IMMUNOLOGY

Systemic Analysis of PPAR  in Mouse Macrophage Populations Reveals Marked Diversity in Expression with Critical Roles in Resolution of Inflammation and Airway Immunity

(2012) E. L. Gautier et al.   JOURNAL OF IMMUNOLOGY

FOXM1 Promotes Allergen-Induced Goblet Cell Metaplasia and Pulmonary Inflammation

(2012) X. Ren et al.   MOLECULAR AND CELLULAR BIOLOGY

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Adherent Human Alveolar Macrophages Exhibit a Transient Pro-Inflammatory Profile That Confounds Responses to Innate Immune Stimulation

(2012) Gillian S. Tomlinson et al.   PLoS One

PPARG Binding Landscapes in Macrophages Suggest a Genome-Wide Contribution of PU.1 to Divergent PPARG Binding in Human and Mouse

(2012) Sebastian Pott et al.   PLoS One

Efficient differentiation and function of human macrophages in humanized CSF-1 mice

(2011) C. Rathinam et al.   BLOOD

The yin and yang of Activin A

(2011) S. Sozzani et al.   BLOOD

Activin A skews macrophage polarization by promoting a proinflammatory phenotype and inhibiting the acquisition of anti-inflammatory macrophage markers

(2011) E. Sierra-Filardi et al.   BLOOD

Bronchoalveolar lavage cell pattern from healthy human lung

(2011) M. Heron et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Foxm1 transcription factor is required for macrophage migration during lung inflammation and tumor formation

(2011) D Balli et al.   ONCOGENE

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Conjugated linoleic acid suppresses the migratory and inflammatory phenotype of the monocyte/macrophage cell

(2010) Sarah McClelland et al.   ATHEROSCLEROSIS

Control of Macrophage Activation and Function by PPARs

(2010) Ajay Chawla   CIRCULATION RESEARCH

Role of NF- B and PPAR-  in lung inflammation induced by monocyte-derived microparticles

(2010) T. Neri et al.   EUROPEAN RESPIRATORY JOURNAL

STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells

(2010) Attila Szanto et al.   IMMUNITY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Activin A induces dendritic cell migration through the polarized release of CXC chemokine ligands 12 and 14

(2009) L. Salogni et al.   BLOOD

Pulmonary alveolar proteinosis, a primary immunodeficiency of impaired GM-CSF stimulation of macrophages

(2009) Bruce C Trapnell et al.   CURRENT OPINION IN IMMUNOLOGY

Activin and related proteins in inflammation: Not just interested bystanders

(2009) David J. Phillips et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Pioglitazone Inhibits Toll-Like Receptor Expression and Activity in Human Monocytes and db/db Mice

(2009) Mohan R. Dasu et al.   ENDOCRINOLOGY

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling

(2009) Andrew J. Fleetwood et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Activation of peroxisome proliferator-activated receptor γ inhibits TNF-α-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocyte chemoattractant protein-1 expression

(2008) Hiroyuki Hounoki et al.   BONE

The many faces of PPARγ: Anti-inflammatory by any means?

(2008) Attila Szanto et al.   IMMUNOBIOLOGY

Activin A Induces Langerhans Cell Differentiation In Vitro and in Human Skin Explants

(2008) Tiziana Musso et al.   PLoS One