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Title
Targeting GM-CSF in inflammatory diseases
Authors
Keywords
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Journal
Nature Reviews Rheumatology
Volume 12, Issue 1, Pages 37-48
Publisher
Springer Nature
Online
2015-12-03
DOI
10.1038/nrrheum.2015.161
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Note: Only part of the references are listed.- Notch signaling mediates granulocyte-macrophage colony-stimulating factor priming-induced transendothelial migration of human eosinophils
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- (2015) Andrew L. Croxford et al. IMMUNITY
- Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System
- (2015) Cynthia Louis et al. JOURNAL OF IMMUNOLOGY
- Pivotal Roles of GM-CSF in Autoimmunity and Inflammation
- (2015) Aoi Shiomi et al. MEDIATORS OF INFLAMMATION
- Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
- (2015) Xiaodi Su et al. NATURE IMMUNOLOGY
- IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases
- (2015) Michele W L Teng et al. NATURE MEDICINE
- Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis
- (2015) Annemarie E. M. van Nieuwenhuijze et al. ARTHRITIS RESEARCH & THERAPY
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- (2015) Bo-Kyung Son et al. Nature Communications
- Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis
- (2015) Luca Piccoli et al. Nature Communications
- A Hitchhiker’s Guide to Myeloid Cell Subsets: Practical Implementation of a Novel Mononuclear Phagocyte Classification System
- (2015) Martin Guilliams et al. Frontiers in Immunology
- Granulocyte macrophage colony-stimulating factor and the intestinal innate immune cell homeostasis in Crohn's disease
- (2014) Jan Däbritz AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- MOR103, a human monoclonal antibody to granulocyte–macrophage colony-stimulating factor, in the treatment of patients with moderate rheumatoid arthritis: results of a phase Ib/IIa randomised, double-blind, placebo-controlled, dose-escalation trial
- (2014) Frank Behrens et al. ANNALS OF THE RHEUMATIC DISEASES
- Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis
- (2014) D E A Greven et al. ANNALS OF THE RHEUMATIC DISEASES
- Interleukin-3/Granulocyte Macrophage Colony–Stimulating Factor Receptor Promotes Stem Cell Expansion, Monocytosis, and Atheroma Macrophage Burden in Mice With Hematopoietic ApoE Deficiency
- (2014) Mi Wang et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation
- (2014) Wanqiang Sheng et al. CELL RESEARCH
- Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating T Helper-1 Adaptive Immunity
- (2014) Ingo Hilgendorf et al. CIRCULATION
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- IL-17 Regulates Systemic Fungal Immunity by Controlling the Functional Competence of NK Cells
- (2014) Eva Bär et al. IMMUNITY
- Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis
- (2014) Georg F. Weber et al. JOURNAL OF EXPERIMENTAL MEDICINE
- GM-CSF but Not IL-17 Is Critical for the Development of Severe Interstitial Lung Disease in SKG Mice
- (2014) Aoi Shiomi et al. JOURNAL OF IMMUNOLOGY
- GM-CSF-Responsive Monocyte-Derived Dendritic Cells Are Pivotal in Th17 Pathogenesis
- (2014) H.-J. Ko et al. JOURNAL OF IMMUNOLOGY
- Efficacy and safety of mavrilimumab in Japanese subjects with rheumatoid arthritis: Findings from a Phase IIa study
- (2014) Tsutomu Takeuchi et al. Modern Rheumatology
- IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology
- (2014) L Chen et al. Mucosal Immunology
- Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
- (2014) Calum C Bain et al. NATURE IMMUNOLOGY
- Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation
- (2014) Katharina M Jeltsch et al. NATURE IMMUNOLOGY
- Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
- (2014) Christoph Schneider et al. NATURE IMMUNOLOGY
- The Closely Related CD103+ Dendritic Cells (DCs) and Lymphoid-Resident CD8+ DCs Differ in Their Inflammatory Functions
- (2014) Zhijun Jiao et al. PLoS One
- Rac2 Controls Tumor Growth, Metastasis and M1-M2 Macrophage Differentiation In Vivo
- (2014) Shweta Joshi et al. PLoS One
- IL-17 and GM-CSF Expression Are Antagonistically Regulated by Human T Helper Cells
- (2014) R. Noster et al. Science Translational Medicine
- Nonclinical safety of mavrilimumab, an anti-GMCSF receptor alpha monoclonal antibody, in cynomolgus monkeys: Relevance for human safety
- (2014) Patricia C. Ryan et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
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- (2014) Alexander V. Misharin et al. Cell Reports
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- (2014) Odette M. Shaw et al. Arthritis & Rheumatology
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- (2014) Helen Benham et al. Arthritis & Rheumatology
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- (2013) Annemarie E. van Nieuwenhuijze et al. AMERICAN JOURNAL OF PATHOLOGY
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- (2012) Yaming Wang et al. NATURE IMMUNOLOGY
- Innate Response Activator B Cells Protect Against Microbial Sepsis
- (2012) P. J. Rauch et al. SCIENCE
- Colony stimulating factors and myeloid cell biology in health and disease
- (2012) John A. Hamilton et al. TRENDS IN IMMUNOLOGY
- Validation of a novel multibiomarker test to assess rheumatoid arthritis disease activity
- (2012) Jeffrey R. Curtis et al. ARTHRITIS CARE & RESEARCH
- Granulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development
- (2012) Andrew D Cook et al. ARTHRITIS RESEARCH & THERAPY
- Mavrilimumab, a human monoclonal antibody targeting GM-CSF receptor- , in subjects with rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase I, first-in-human study
- (2011) G. R. Burmester et al. ANNALS OF THE RHEUMATIC DISEASES
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- (2011) E. Sierra-Filardi et al. BLOOD
- GM-CSF increases cross-presentation and CD103 expression by mouse CD8+ spleen dendritic cells
- (2011) Yifan Zhan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2011) F. M. Botelho et al. EUROPEAN RESPIRATORY JOURNAL
- The Th17 immune response is controlled by the Rel–RORγ–RORγT transcriptional axis
- (2011) Qingguo Ruan et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2011) L. M. Liontos et al. JOURNAL OF IMMUNOLOGY
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- (2011) I. K. Campbell et al. JOURNAL OF IMMUNOLOGY
- IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
- (2011) Thomas Krausgruber et al. NATURE IMMUNOLOGY
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- (2011) Laura Codarri et al. NATURE IMMUNOLOGY
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- (2011) Mohamed El-Behi et al. NATURE IMMUNOLOGY
- Neutralizing Granulocyte/Macrophage Colony–Stimulating Factor Inhibits Cigarette Smoke–induced Lung Inflammation
- (2010) Ross Vlahos et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Granulocyte/Macrophage Colony–Stimulating Factor Causes a Paradoxical Increase in the BH3-Only Pro-Apoptotic Protein Bim in Human Neutrophils
- (2010) Andrew S. Cowburn et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- GM-CSF-Facilitated Dendritic Cell Recruitment and Survival Govern the Intestinal Mucosal Response to a Mouse Enteric Bacterial Pathogen
- (2010) Yoshihiro Hirata et al. Cell Host & Microbe
- GM-CSF–dependent, CD103+dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization
- (2010) Irah L. King et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Hematopoietic colony-stimulating factors: new players in tumor–nerve interactions
- (2010) Sebastian Stösser et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Anticytokine autoantibodies in infectious diseases: pathogenesis and mechanisms
- (2010) Sarah K Browne et al. LANCET INFECTIOUS DISEASES
- The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases
- (2009) John A. Hamilton et al. ARTHRITIS AND RHEUMATISM
- Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease
- (2009) I. L. King et al. BLOOD
- Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps
- (2009) S Yousefi et al. CELL DEATH AND DIFFERENTIATION
- GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling
- (2009) Andrew J. Fleetwood et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Hematopoietic colony–stimulating factors mediate tumor-nerve interactions and bone cancer pain
- (2009) Matthias Schweizerhof et al. NATURE MEDICINE
- G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis
- (2009) Ann L. Cornish et al. Nature Reviews Rheumatology
- Human GM-CSF Autoantibodies and Reproduction of Pulmonary Alveolar Proteinosis
- (2009) Takuro Sakagami et al. NEW ENGLAND JOURNAL OF MEDICINE
- Combined blockade of granulocyte-macrophage colony stimulating factor and interleukin 17 pathways potently suppresses chronic destructive arthritis in a tumour necrosis factor -independent mouse model
- (2008) C Plater-Zyberk et al. ANNALS OF THE RHEUMATIC DISEASES
- Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis
- (2008) Paul J. Egan et al. ARTHRITIS AND RHEUMATISM
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- (2008) D. Metcalf BLOOD
- Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects
- (2008) K. Uchida et al. BLOOD
- The Signal Transducer STAT5 Inhibits Plasmacytoid Dendritic Cell Development by Suppressing Transcription Factor IRF8
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- GM-CSF mediates autoimmunity by enhancing IL-6–dependent Th17 cell development and survival
- (2008) Ivo Sonderegger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- In vitro affinity maturation of human GM-CSF antibodies by targeted CDR-diversification
- (2008) Stefan Steidl et al. MOLECULAR IMMUNOLOGY
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