Polymorphism rs1385129 Within Glut1 Gene SLC2A1 Is Linked to Poor CD4+ T Cell Recovery in Antiretroviral-Treated HIV+ Individuals

Hyperactivation of mammalian target of rapamycin complex 1 by HIV-1 is necessary for virion production and latent viral reactivation

(2017) Binod Kumar et al.   FASEB JOURNAL

Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection

(2017) Clovis S. Palmer et al.   FEBS LETTERS

IL-7 Restores T Lymphocyte Immunometabolic Failure in Septic Shock Patients through mTOR Activation

(2017) Fabienne Venet et al.   JOURNAL OF IMMUNOLOGY

Assessment of metabolic and mitochondrial dynamics in CD4+ and CD8+ T cells in virologically suppressed HIV-positive individuals on combination antiretroviral therapy

(2017) Jesse J. R. Masson et al.   PLoS One

Role of glucose metabolism related gene GLUT1 in the occurrence and prognosis of colorectal cancer

(2017) Wenming Feng et al.   Oncotarget

HIV-1 Activates T Cell Signaling Independently of Antigen to Drive Viral Spread

(2017) Alice C.L. Len et al.   Cell Reports

A Subset of Extreme Human Immunodeficiency Virus (HIV) Controllers Is Characterized by a Small HIV Blood Reservoir and a Weak T-Cell Activation Level

(2017) Etienne Canouï et al.   Open Forum Infectious Diseases

The mTOR Complex Controls HIV Latency

(2016) Emilie Besnard et al.   Cell Host & Microbe

CD4+ T-cell gene expression of healthy donors, HIV-1 and elite controllers: Immunological chaos

(2016) G. Nunnari et al.   CYTOKINE

Emerging Role and Characterization of Immunometabolism: Relevance to HIV Pathogenesis, Serious Non-AIDS Events, and a Cure

(2016) Clovis S. Palmer et al.   JOURNAL OF IMMUNOLOGY

Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+T CellsIn Vitro

(2016) Jennifer M. Zerbato et al.   JOURNAL OF VIROLOGY

MicroRNA Profile in CD8+ T-Lymphocytes from HIV-Infected Individuals: Relationship with Antiviral Immune Response and Disease Progression

(2016) Lander Egaña-Gorroño et al.   PLoS One

Analysis of Host Gene Expression Profile in HIV-1 and HIV-2 Infected T-Cells

(2016) Krishnakumar Devadas et al.   PLoS One

Nutrients and the microenvironment to feed a T cell army

(2016) Marc O. Johnson et al.   SEMINARS IN IMMUNOLOGY

Metabolic pathways in T cell activation and lineage differentiation

(2016) Luís Almeida et al.   SEMINARS IN IMMUNOLOGY

Apoptotic transition of senescent cells accompanied with mitochondrial hyper-function

(2016) Danli Wang et al.   Oncotarget

Tuning of AKT-pathway by Nef and its blockade by protease inhibitors results in limited recovery in latently HIV infected T-cell line

(2016) Amit Kumar et al.   Scientific Reports

Manipulation of immunometabolism by HIV—accessories to the crime?

(2016) Nicholas J Matheson et al.   Current Opinion in Virology

Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection

(2016) Korey R. Demers et al.   PLoS Pathogens

Metabolic Complications and Glucose Metabolism in HIV Infection: A Review of the Evidence

(2016) Amanda L. Willig et al.   Current HIV/AIDS Reports

Glucose Metabolism in T Cells and Monocytes: New Perspectives in HIV Pathogenesis

(2016) Clovis S. Palmer et al.   EBioMedicine

Oxidative Stress Predicts All-Cause Mortality in HIV-Infected Patients

(2016) Mar Masiá et al.   PLoS One

Does rapid HIV disease progression prior to combination antiretroviral therapy hinder optimal CD4+ T-cell recovery once HIV-1 suppression is achieved?

(2015) Inma Jarrin et al.   AIDS

Chronic lymphocytic leukemia and the Warburg effect

(2015) C. Moreno   BLOOD

Current topics in HIV-1 pathogenesis: The emergence of deregulated immuno-metabolism in HIV-infected subjects

(2015) Xavier Dagenais-Lussier et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Regulators of Glucose Metabolism in CD4+ and CD8+ T Cells

(2015) Clovis S. Palmer et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

The serologic decoy receptor 3 (DcR3) levels are associated with slower disease progression in HIV-1/AIDS patients

(2015) Yu-Ting Lin et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Whisper mutations: cryptic messages within the genetic code

(2015) R Fåhraeus et al.   ONCOGENE

Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer

(2015) Ying Piao et al.   PLoS One

Impact of HIV-1 Subtype on the Time to CD4+ T-Cell Recovery in Combination Antiretroviral Therapy (cART)-Experienced Patients

(2015) Wei Zhen Chow et al.   PLoS One

Identification of Genes Whose Expression Profile Is Associated with Non-Progression towards AIDS Using eQTLs

(2015) Jean-Louis Spadoni et al.   PLoS One

Comparison of HIV-1 nef and gag Variations and Host HLA Characteristics as Determinants of Disease Progression among HIV-1 Vertically Infected Kenyan Children

(2015) Matilda Chelimo Saina et al.   PLoS One

Harnessing the PI3K/Akt/mTOR pathway in T-cell acute lymphoblastic leukemia: Eliminating activity by targeting at different levels

(2015) Daniela Bressanin et al.   Oncotarget

HIF-1α and GLUT1 Gene Expression is Associated with Chemoresistance of Acute Myeloid Leukemia

(2014) Kui Song et al.   Asian Pacific Journal of Cancer Prevention

The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function

(2014) Andrew N. Macintyre et al.   Cell Metabolism

Glucose Uptake Is Limiting in T Cell Activation and Requires CD28-Mediated Akt-Dependent and Independent Pathways

(2014) S. R. Jacobs et al.   JOURNAL OF IMMUNOLOGY

Foxp3-mediated inhibition of Akt inhibits Glut1 (glucose transporter 1) expression in human T regulatory cells

(2014) Samik Basu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Genetic variants in AKT1 gene were associated with risk and survival of OSCC in Chinese Han Population

(2014) Yun Wang et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

A systematic review of definitions of extreme phenotypes of HIV control and progression

(2013) Deepti Gurdasani et al.   AIDS

Increased glucose metabolic activity is associated with CD4+ T-cell activation and depletion during chronic HIV infection

(2013) Clovis S. Palmer et al.   AIDS

Genotyping analysis and 18FDG uptake in breast cancer patients: a preliminary research

(2013) Valentina Bravatà et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Different Immunological Phenotypes Associated with Preserved CD4+ T Cell Counts in HIV-Infected Controllers and Viremic Long Term Non-Progressors

(2013) Julie Christine Gaardbo et al.   PLoS One

Risk of clinical progression among patients with immunological nonresponse despite virological suppression after combination antiretroviral treatment

(2012) Giuseppe Lapadula et al.   AIDS

Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog

(2012) Geneviève Doyon et al.   AIDS

Glut1-mediated glucose transport regulates HIV infection

(2012) S. Loisel-Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic pathways in T cell fate and function

(2012) Valerie A. Gerriets et al.   TRENDS IN IMMUNOLOGY

High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort

(2011) Damalie Nakanjako et al.   BMC INFECTIOUS DISEASES

AKT1 polymorphisms and survival of early stage non-small cell lung cancer

(2011) Min Jung Kim et al.   JOURNAL OF SURGICAL ONCOLOGY

Intracellular reactive oxygen species are essential for PI3K/Akt/mTOR-dependent IL-7-mediated viability of T-cell acute lymphoblastic leukemia cells

(2011) A Silva et al.   LEUKEMIA

Protective HIV-specific CD8+ T cells evade Treg cell suppression

(2011) Shokrollah Elahi et al.   NATURE MEDICINE

Clinical Predictors of Immune Reconstitution following Combination Antiretroviral Therapy in Patients from the Australian HIV Observational Database

(2011) Reena Rajasuriar et al.   PLoS One

Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease

(2011) Jing Wu et al.   Retrovirology

Glucocorticoid-induced cell death is mediated through reduced glucose metabolism in lymphoid leukemia cells

(2011) E Buentke et al.   Blood Cancer Journal

AKT1 polymorphisms are associated with risk for metabolic syndrome

(2010) Joseph M. Devaney et al.   HUMAN GENETICS

The XbaI G>T Polymorphism of the Glucose Transporter 1 Gene Modulates 18F-FDG Uptake and Tumor Aggressiveness in Breast Cancer

(2010) F. Grabellus et al.   JOURNAL OF NUCLEAR MEDICINE

Effects of thymic selection of the T-cell repertoire on HLA class I-associated control of HIV infection

(2010) Andrej Košmrlj et al.   NATURE

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

CD57+ T lymphocytes and functional immune deficiency

(2009) Daniele Focosi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

A novel role for adiponectin in regulating the immune responses in chronic hepatitis C virus infection

(2008) Clovis Palmer et al.   HEPATOLOGY