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Title
Tumor Necrosis Factor α and Regulatory T Cells in Oncoimmunology
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-03-12
DOI
10.3389/fimmu.2018.00444
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- (2017) Frederick Arce Vargas et al. IMMUNITY
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- (2017) Madhumita Das et al. IMMUNOLOGICAL REVIEWS
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- (2017) Bertrand Allard et al. IMMUNOLOGICAL REVIEWS
- Transmembrane tumor necrosis factor-α promotes the recruitment of MDSCs to tumor tissue by upregulating CXCR4 expression via TNFR2
- (2017) Hongping Ba et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Risk of Cancer Recurrence Among Individuals Exposed to Antitumor Necrosis Factor Therapy
- (2017) Dejan Micic et al. JOURNAL OF CLINICAL GASTROENTEROLOGY
- Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs
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- Emerging targets in cancer immunotherapy
- (2017) Samantha Burugu et al. SEMINARS IN CANCER BIOLOGY
- TIGIT: A Key Inhibitor of the Cancer Immunity Cycle
- (2017) Nicholas A. Manieri et al. TRENDS IN IMMUNOLOGY
- Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs
- (2017) Heather Torrey et al. Science Signaling
- Combination immunotherapy: a road map
- (2017) Patrick A. Ott et al. Journal for ImmunoTherapy of Cancer
- TNF-α priming enhances CD4 + FoxP3 + regulatory T-cell suppressive function in murine GVHD prevention and treatment
- (2016) Antonio Pierini et al. BLOOD
- Control of GVHD by regulatory T cells depends on TNF produced by T cells and TNFR2 expressed by regulatory T cells
- (2016) M. Leclerc et al. BLOOD
- Low-dose interleukin-2 impairs host anti-tumor immunity and inhibits therapeutic responses in a mouse model of melanoma
- (2016) Andrew Zloza et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Lymphocyte-activation gene-3, an important immune checkpoint in cancer
- (2016) Yayi He et al. CANCER SCIENCE
- Regulatory T cells in cancer immunotherapy
- (2016) Atsushi Tanaka et al. CELL RESEARCH
- Reversing T-cell Dysfunction and Exhaustion in Cancer
- (2016) H. M. Zarour CLINICAL CANCER RESEARCH
- Immunotherapy and Novel Combinations in Oncology: Current Landscape, Challenges, and Opportunities
- (2016) KM Morrissey et al. CTS-Clinical and Translational Science
- Rationale for anti-GITR cancer immunotherapy
- (2016) Deborah A. Knee et al. EUROPEAN JOURNAL OF CANCER
- Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion
- (2016) Martin Chopra et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Tumor-necrosis factor impairs CD4+ T cell–mediated immunological control in chronic viral infection
- (2016) Marc Beyer et al. NATURE IMMUNOLOGY
- Suppressive activity of human regulatory T cells is maintained in the presence of TNF
- (2016) Bruno Zaragoza et al. NATURE MEDICINE
- The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
- (2016) Danny N. Khalil et al. Nature Reviews Clinical Oncology
- IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance
- (2016) David H. Munn et al. TRENDS IN IMMUNOLOGY
- Infliximab enhances the therapeutic effects of 5-fluorouracil resulting in tumor regression in colon cancer
- (2016) Fen Liu et al. OncoTargets and Therapy
- Loss of immune tolerance to IL-2 in type 1 diabetes
- (2016) Louis Pérol et al. Nature Communications
- TNF Neutralization Results in the Delay of Transplantable Tumor Growth and Reduced MDSC Accumulation
- (2016) Kamar-Sulu N. Atretkhany et al. Frontiers in Immunology
- Expression of TNFR2 by regulatory T cells in peripheral blood is correlated with clinical pathology of lung cancer patients
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- TNF Receptor-2 Facilitates an Immunosuppressive Microenvironment in the Liver to Promote the Colonization and Growth of Hepatic Metastases
- (2015) B. Ham et al. CANCER RESEARCH
- Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms
- (2015) Jamie B. Spangler et al. IMMUNITY
- Immunity, inflammation, and cancer: an eternal fight between good and evil
- (2015) Shabnam Shalapour et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2015) Kristen E. Pauken et al. TRENDS IN IMMUNOLOGY
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- (2015) Kevin Van der Jeught et al. Oncotarget
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- (2015) Aaron Arvey et al. eLife
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- (2013) J. Couzin-Frankel SCIENCE
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- (2012) Sung W. Choi et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- First- and Second-Line Systemic Treatment of Acute Graft-versus-Host Disease: Recommendations of the American Society of Blood and Marrow Transplantation
- (2012) Paul J. Martin et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
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- (2012) Suzanne L Topalian et al. CURRENT OPINION IN IMMUNOLOGY
- Levels of Circulating Th17 Cells and Regulatory T Cells in Ankylosing Spondylitis Patients with an Inadequate Response to Anti−TNF-α Therapy
- (2012) Li Xueyi et al. JOURNAL OF CLINICAL IMMUNOLOGY
- TNF signaling drives myeloid-derived suppressor cell accumulation
- (2012) Xueqiang Zhao et al. JOURNAL OF CLINICAL INVESTIGATION
- Cancer and Innate Immune System Interactions
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- (2011) H. Kulbe et al. CANCER RESEARCH
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- (2011) Caroline Robert et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2010) C. G. Brunstein et al. BLOOD
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- (2010) S. Sangaletti et al. CANCER RESEARCH
- Selective Depletion of Foxp3+ Regulatory T Cells Improves Effective Therapeutic Vaccination against Established Melanoma
- (2010) K. Klages et al. CANCER RESEARCH
- Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+regulatory T cells in human peripheral blood
- (2010) Xin Chen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity
- (2010) Thomas R. Malek et al. IMMUNITY
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- (2010) Yenkel Grinberg-Bleyer et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2010) Julie R. Brahmer et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2010) A. Zanin-Zhorov et al. SCIENCE
- CD4+CD25+ Regulatory T Cell Depletion Improves the Graft-Versus-Tumor Effect of Donor Lymphocytes After Allogeneic Hematopoietic Stem Cell Transplantation
- (2010) S. Maury et al. Science Translational Medicine
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- (2009) Karl S. Peggs et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2009) James LM Ferrara et al. LANCET
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- (2009) S. E. Erdman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Manuel Ramos-Casals et al. Current Rheumatology Reports
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- (2008) S. W. Choi et al. BLOOD
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