Expression of TNFR2 by regulatory T cells in peripheral blood is correlated with clinical pathology of lung cancer patients

IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells

(2015) Xin Chen et al.   FASEB JOURNAL

Lenalidomide-based maintenance therapy reduces TNF receptor 2 on CD4 T cells and enhances immune effector function in acute myeloid leukemia patients

(2014) Chindu Govindaraj et al.   AMERICAN JOURNAL OF HEMATOLOGY

Cutting Edge: Expression of TNFR2 Defines a Maximally Suppressive Subset of Mouse CD4+CD25+FoxP3+ T Regulatory Cells: Applicability to Tumor-Infiltrating T Regulatory Cells

(2014) X. Chen et al.   JOURNAL OF IMMUNOLOGY

Variation of Blood T Lymphocyte Subgroups in Patients with Non- small Cell Lung Cancer

(2013) Wen-Jing Wang et al.   Asian Pacific Journal of Cancer Prevention

Reducing TNF Receptor 2 + Regulatory T Cells via the Combined Action of Azacitidine and the HDAC Inhibitor, Panobinostat for Clinical Benefit in Acute Myeloid Leukemia Patients

(2013) Chindu Govindaraj et al.   CLINICAL CANCER RESEARCH

Impaired Th1 immunity in ovarian cancer patients is mediated by TNFR2+ Tregs within the tumor microenvironment

(2013) Chindu Govindaraj et al.   CLINICAL IMMUNOLOGY

TNFR2 Is Critical for the Stabilization of the CD4+Foxp3+ Regulatory T Cell Phenotype in the Inflammatory Environment

(2013) X. Chen et al.   JOURNAL OF IMMUNOLOGY

TNFR2 Expression on CD25hiFOXP3+ T Cells Induced upon TCR Stimulation of CD4 T Cells Identifies Maximal Cytokine-Producing Effectors

(2013) Chindu Govindaraj et al.   Frontiers in Immunology

Phenotypic and functional characteristics of CD4+CD39+ FOXP3+ and CD4+CD39+FOXP3neg T-cell subsets in cancer patients

(2012) Patrick J. Schuler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD4+CD25+CD127low/− T Cells: A More Specific Treg Population in Human Peripheral Blood

(2012) Ning Yu et al.   INFLAMMATION

Increase of regulatory T cells in metastatic stage and CTLA-4 over expression in lymphocytes of patients with non-small cell lung cancer (NSCLC)

(2012) Nasrollah Erfani et al.   LUNG CANCER

TNF optimally activatives regulatory T cells by inducing TNF receptor superfamily members TNFR2, 4-1BB and OX40

(2011) Ryoko Hamano et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TNFR2 on non-haematopoietic cells is required for Foxp3+Treg-cell function and disease suppression in EAE

(2011) Niki Tsakiri et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-17 + Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer

(2011) Ilona Kryczek et al.   JOURNAL OF IMMUNOLOGY

Natural but Not Inducible Regulatory T Cells Require TNF-  Signaling for In Vivo Function

(2011) W. J. Housley et al.   JOURNAL OF IMMUNOLOGY

Notch3 and Canonical NF- B Signaling Pathways Cooperatively Regulate Foxp3 Transcription

(2011) A. Barbarulo et al.   JOURNAL OF IMMUNOLOGY

Prognostic potential of FOXP3 expression in non-small cell lung cancer cells combined with tumor-infiltrating regulatory T cells

(2011) Hiroyuki Tao et al.   LUNG CANCER

Lower Frequency of CD62Lhighand Higher Frequency of TNFR2+Tregs Are Associated with Inflammatory Conditions in Type 1 Diabetic Patients

(2011) Monika Ryba et al.   MEDIATORS OF INFLAMMATION

Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+regulatory T cells in human peripheral blood

(2010) Xin Chen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Novel application of Ki67 to quantify antigen-specific in vitro lymphoproliferation

(2010) Andreia Soares et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Expression of Costimulatory TNFR2 Induces Resistance of CD4+FoxP3- Conventional T Cells to Suppression by CD4+FoxP3+ Regulatory T Cells

(2010) X. Chen et al.   JOURNAL OF IMMUNOLOGY

Agonist Anti-GITR Monoclonal Antibody Induces Melanoma Tumor Immunity in Mice by Altering Regulatory T Cell Stability and Intra-Tumor Accumulation

(2010) Adam D. Cohen et al.   PLoS One

Membrane Tumor Necrosis Factor (TNF) Induces p100 Processing via TNF Receptor-2 (TNFR2)

(2009) Hilka Rauert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parasite-Dependent Expansion of TNF Receptor II–Positive Regulatory T Cells with Enhanced Suppressive Activity in Adults with Severe Malaria

(2009) Gabriela Minigo et al.   PLoS Pathogens

Tumor eradication after cyclophosphamide depends on concurrent depletion of regulatory T cells: a role for cycling TNFR2-expressing effector-suppressor T cells in limiting effective chemotherapy

(2008) Robbert G. van der Most et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY