Tumor-necrosis factor impairs CD4+ T cell–mediated immunological control in chronic viral infection

T-cell exhaustion, co-stimulation and clinical outcome in autoimmunity and infection

(2015) Eoin F. McKinney et al.   NATURE

IL-6 as a keystone cytokine in health and disease

(2015) Christopher A Hunter et al.   NATURE IMMUNOLOGY

Molecular and Transcriptional Basis of CD4+ T Cell Dysfunction during Chronic Infection

(2014) Alison Crawford et al.   IMMUNITY

TNF-  levels in HIV-infected patients after long-term suppressive cART persist as high as in elderly, HIV-uninfected subjects

(2014) R. S. De Pablo-Bernal et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

HIV-1 Tat Protein Induces PD-L1 (B7-H1) Expression on Dendritic Cells through Tumor Necrosis Factor Alpha- and Toll-Like Receptor 4-Mediated Mechanisms

(2014) R. Planes et al.   JOURNAL OF VIROLOGY

Reactive oxygen species delay control of lymphocytic choriomeningitis virus

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Systemic Effects of Inflammation on Health during Chronic HIV Infection

(2013) Steven G. Deeks et al.   IMMUNITY

Tumor Necrosis Factor-α Blocks Differentiation and Enhances Suppressive Activity of Immature Myeloid Cells during Chronic Inflammation

(2013) Moshe Sade-Feldman et al.   IMMUNITY

Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection

(2013) E. B. Wilson et al.   SCIENCE

Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

(2013) J. R. Teijaro et al.   SCIENCE

TGF-β Signalling Is Required for CD4+ T Cell Homeostasis But Dispensable for Regulatory T Cell Function

(2013) Anna Śledzińska et al.   PLOS BIOLOGY

Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory

(2012) Travis A. Doering et al.   IMMUNITY

Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation

(2011) Marc Beyer et al.   NATURE IMMUNOLOGY

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

T cell exhaustion

(2011) E John Wherry   NATURE IMMUNOLOGY

Safety of anti-tumour necrosis factor agents in patients with chronic hepatitis C infection: a systematic review

(2011) A. M. G. Brunasso et al.   RHEUMATOLOGY

HIV-specific CD4 T cells and immune control of viral replication

(2011) Filippos Porichis et al.   Current Opinion in HIV and AIDS

Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells

(2011) Ben Youngblood et al.   Current Opinion in HIV and AIDS

Features of responding T cells in cancer and chronic infection

(2010) Peter S Kim et al.   CURRENT OPINION IN IMMUNOLOGY

Transcriptional Profiling of CD4 T Cells Identifies Distinct Subgroups of HIV-1 Elite Controllers

(2010) F. Vigneault et al.   JOURNAL OF VIROLOGY

Tumor necrosis factor blockade and the risk of viral infection

(2010) Seo Young Kim et al.   Nature Reviews Rheumatology

Role of antigen persistence and dose for CD4+ T-cell exhaustion and recovery

(2010) S. Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide mRNA Expression Correlates of Viral Control in CD4+ T-Cells from HIV-1-Infected Individuals

(2010) Margalida Rotger et al.   PLoS Pathogens

Infliximab therapy for HIV positive Crohn's disease: A case report

(2009) Syed F. Habib et al.   Journal of Crohns & Colitis

A Vital Role for Interleukin-21 in the Control of a Chronic Viral Infection

(2009) J. S. Yi et al.   SCIENCE

IL-21 Is Required to Control Chronic Viral Infection

(2009) H. Elsaesser et al.   SCIENCE

IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection

(2009) A. Frohlich et al.   SCIENCE

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology