The Role of Natural Killer T Cells in Cancer—A Phenotypical and Functional Approach
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Title
The Role of Natural Killer T Cells in Cancer—A Phenotypical and Functional Approach
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-02-27
DOI
10.3389/fimmu.2018.00367
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Note: Only part of the references are listed.- Dendritic cells combined with tumor cells and α-galactosylceramide induce a potent, therapeutic and NK-cell dependent antitumor immunity in B cell lymphoma
- (2017) Laura Escribà-Garcia et al. Journal of Translational Medicine
- Invariant natural killer T infiltration in neuroblastoma with favorable outcome
- (2017) Tomoro Hishiki et al. PEDIATRIC SURGERY INTERNATIONAL
- Chimeric antigen receptor–engineered natural killer and natural killer T cells for cancer immunotherapy
- (2017) Dominique Bollino et al. Translational Research
- A different representation of natural T cells and natural killer cells between tumor-infiltrating and periphery lymphocytes in human hepatocellular carcinoma
- (2017) Xiao-Feng Li et al. Oncology Letters
- CD3xPDL1 bi-specific T cell engager (BiTE) simultaneously activates T cells and NKT cells, kills PDL1+ tumor cells, and extends the survival of tumor-bearing humanized mice
- (2017) Lucas A. Horn et al. Oncotarget
- Natural Killer T-cell Immunotherapy in Combination with Chemotherapy-Induced Immunogenic Cell Death Targets Metastatic Breast Cancer
- (2017) Simon Gebremeskel et al. Cancer Immunology Research
- Natural Killer T Cells in Cancer Immunotherapy
- (2017) Shiny Nair et al. Frontiers in Immunology
- Natural Killer T Cell-Targeted Immunotherapy Mediating Long-term Memory Responses and Strong Antitumor Activity
- (2017) Nyambayar Dashtsoodol et al. Frontiers in Immunology
- Improved Detection of Cytokines Produced by Invariant NKT Cells
- (2017) Duygu Sag et al. Scientific Reports
- Blockade of programmed death-1/programmed death ligand pathway enhances the antitumor immunity of human invariant natural killer T cells
- (2016) Toshiko Kamata et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- NKT cell subsets as key participants in liver physiology and pathology
- (2016) Keya Bandyopadhyay et al. Cellular & Molecular Immunology
- Development of invariant natural killer T cells
- (2016) Laurent Gapin CURRENT OPINION IN IMMUNOLOGY
- CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo
- (2016) Gengwen Tian et al. JOURNAL OF CLINICAL INVESTIGATION
- The cytokine profile of human NKT cells and PBMCs is dependent on donor sex and stimulus
- (2016) Hannah Bernin et al. MEDICAL MICROBIOLOGY AND IMMUNOLOGY
- Lactic acid in tumor microenvironments causes dysfunction of NKT cells by interfering with mTOR signaling
- (2016) Di Xie et al. Science China-Life Sciences
- Efficient Regeneration of Human Vα24+Invariant Natural Killer T Cells and Their Anti-Tumor Activity In Vivo
- (2016) Daisuke Yamada et al. STEM CELLS
- Altered phenotypic and functional characteristics of CD3+CD56+ NKT-like cells in human gastric cancer
- (2016) Liu-sheng Peng et al. Oncotarget
- Cellular Adjuvant Properties, Direct Cytotoxicity of Re-differentiated Vα24 Invariant NKT-like Cells from Human Induced Pluripotent Stem Cells
- (2016) Shuichi Kitayama et al. Stem Cell Reports
- The Prognostic Impact of NK/NKT Cell Density in Periampullary Adenocarcinoma Differs by Morphological Type and Adjuvant Treatment
- (2016) Sebastian Lundgren et al. PLoS One
- Thymosin alpha1 enhanced cytotoxicity of iNKT cells against colon cancer via upregulating CD1d expression
- (2015) Chao Ni et al. CANCER LETTERS
- Discovery of NKT cells and development of NKT cell-targeted anti-tumor immunotherapy
- (2015) Masaru TANIGUCHI et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- The Regulatory Role of Invariant NKT Cells in Tumor Immunity
- (2015) Rosanna M. McEwen-Smith et al. Cancer Immunology Research
- The Role of Invariant Natural Killer T Cells in Dendritic Cell Licensing, Cross-Priming, and Memory CD8+ T Cell Generation
- (2015) Catherine Gottschalk et al. Frontiers in Immunology
- Type II NKT Cells in Inflammation, Autoimmunity, Microbial Immunity, and Cancer
- (2015) Idania Marrero et al. Frontiers in Immunology
- Tolerogenic Dendritic Cells for Regulatory T Cell Induction in Man
- (2015) Verena K. Raker et al. Frontiers in Immunology
- Natural killer T cell activation overcomes immunosuppression to enhance clearance of postsurgical breast cancer metastasis in mice
- (2015) Simon Gebremeskel et al. OncoImmunology
- Invariant NKT cells with chimeric antigen receptor provide a novel platform for safe and effective cancer immunotherapy
- (2014) A. Heczey et al. BLOOD
- The immunoregulatory role of type I and type II NKT cells in cancer and other diseases
- (2014) Masaki Terabe et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- The Aberrant Expression of Stimulatory and Inhibitory Killer Immunoglobulin-Like Receptors in NK- and NKT-Cells Contributes to Lupus
- (2014) Yanyan Bai et al. Clinical Laboratory
- IL-13Rα2-bearing, type II NKT cells reactive to sulfatide self-antigen populate the mucosa of ulcerative colitis
- (2014) Ivan J Fuss et al. GUT
- Different subsets of natural killer T cells may vary in their roles in health and disease
- (2014) Vipin Kumar et al. IMMUNOLOGY
- IL-10–producing NKT10 cells are a distinct regulatory invariant NKT cell subset
- (2014) Duygu Sag et al. JOURNAL OF CLINICAL INVESTIGATION
- CD1d expression in renal cell carcinoma is associated with higher relapse rates, poorer cancer-specific and overall survival
- (2014) Tsung Wen Chong et al. JOURNAL OF CLINICAL PATHOLOGY
- NKG2A Inhibits Invariant NKT Cell Activation in Hepatic Injury
- (2014) T. Kawamura et al. JOURNAL OF IMMUNOLOGY
- Circulating Myeloid Dendritic Cells of Advanced Cancer Patients Result in Reduced Activation and a Biased Cytokine Profile in Invariant NKT Cells
- (2014) H. J. J. van der Vliet et al. JOURNAL OF IMMUNOLOGY
- Switching Invariant Natural Killer T (iNKT) Cell Response from Anticancerous to Anti-Inflammatory Effect: Molecular Bases
- (2014) Xavier Laurent et al. JOURNAL OF MEDICINAL CHEMISTRY
- Inhibition of Tumor Angiogenesis by Interferon-γ by Suppression of Tumor-Associated Macrophage Differentiation
- (2014) Tao Sun et al. ONCOLOGY RESEARCH
- Polyclonal type II natural killer T cells require PLZF and SAP for their development and contribute to CpG-mediated antitumor response
- (2014) J. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Function of CD3+CD56+NKT-Like Cells in HIV-Infected Individuals
- (2014) Yongjun Jiang et al. Biomed Research International
- NKT Cell Networks in the Regulation of Tumor Immunity
- (2014) Faith C. Robertson et al. Frontiers in Immunology
- Type II natural killer T cells foster the antitumor activity of CpG-oligodeoxynucleotides
- (2014) Jie Zhao et al. OncoImmunology
- Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition
- (2013) Eric O. Long et al. Annual Review of Immunology
- Molecular mechanisms of T-cell anergy
- (2013) E. M. Kuklina BIOCHEMISTRY-MOSCOW
- Medulloblastoma expresses CD1d and can be targeted for immunotherapy with NKT cells
- (2013) Daofeng Liu et al. CLINICAL IMMUNOLOGY
- T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment
- (2013) Joel Crespo et al. CURRENT OPINION IN IMMUNOLOGY
- Natural killer T cell anergy, co-stimulatory molecules and immunotherapeutic interventions
- (2013) Avadhesh Kumar Singh et al. HUMAN IMMUNOLOGY
- Multiplex and Genome-Wide Analyses Reveal Distinctive Properties of KIR+ and CD56+ T Cells in Human Blood
- (2013) W. K. Chan et al. JOURNAL OF IMMUNOLOGY
- Nod1 and Nod2 Enhance TLR-Mediated Invariant NKT Cell Activation during Bacterial Infection
- (2013) T. Selvanantham et al. JOURNAL OF IMMUNOLOGY
- Cytokine patterns in patients with cancer: a systematic review
- (2013) Bodo E Lippitz LANCET ONCOLOGY
- Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation
- (2013) M. Salio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs
- (2013) R. V. V. Tatituri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Altered Invariant Natural Killer T cell Subsets and its Functions in Patients with Oral Squamous Cell Carcinoma
- (2013) A. K. Singh et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Natural Cytotoxicity Receptors: Broader Expression Patterns and Functions in Innate and Adaptive Immune Cells
- (2013) Kelly Hudspeth et al. Frontiers in Immunology
- The Critical Role of the Tumor Microenvironment in Shaping Natural Killer Cell-Mediated Anti-Tumor Immunity
- (2013) Joanna Baginska et al. Frontiers in Immunology
- NKG2D ligand tumor expression and association with clinical outcome in early breast cancer patients: an observational study
- (2012) Esther M de Kruijf et al. BMC CANCER
- CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses
- (2012) Stéphanie Corgnac et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Induced pluripotency as a potential path towards iNKT cell-mediated cancer immunotherapy
- (2012) Hiroshi Watarai et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Accumulation of Activated Invariant Natural Killer T Cells in the Tumor Microenvironment after α-Galactosylceramide-Pulsed Antigen Presenting Cells
- (2012) Kaoru Nagato et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Circulating Invariant Natural Killer T-Cell Numbers Predict Outcome in Head and Neck Squamous Cell Carcinoma: Updated Analysis With 10-Year Follow-Up
- (2012) Famke L. Schneiders et al. JOURNAL OF CLINICAL ONCOLOGY
- Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4+ T Cell Help
- (2012) E. Tonti et al. JOURNAL OF IMMUNOLOGY
- Comparison of Clinical and Immunological Effects of Intravenous and Intradermal Administration of -GalactosylCeramide (KRN7000)-Pulsed Dendritic Cells
- (2011) A. J. Nicol et al. CLINICAL CANCER RESEARCH
- Anti-tumor immune responses induced by iNKT cell-based immunotherapy for lung cancer and head and neck cancer
- (2011) Shinichiro Motohashi et al. CLINICAL IMMUNOLOGY
- Developing understanding of the roles of CD1d-restricted T cell subsets in cancer: Reversing tumor-induced defects
- (2011) Mark A. Exley et al. CLINICAL IMMUNOLOGY
- Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis
- (2011) Sandrine Aspeslagh et al. EMBO JOURNAL
- NKG2D performs two functions in invariant NKT cells: Direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d
- (2011) Carlotta Kuylenstierna et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Mouse and human iNKT cell agonist β-mannosylceramide reveals a distinct mechanism of tumor immunity
- (2011) Jessica J. O’Konek et al. JOURNAL OF CLINICAL INVESTIGATION
- Proinflammatory Environment Dictates the IL-17-Producing Capacity of Human Invariant NKT Cells
- (2011) L. Moreira-Teixeira et al. JOURNAL OF IMMUNOLOGY
- Rapamycin Combined with TGF- Converts Human Invariant NKT Cells into Suppressive Foxp3+ Regulatory Cells
- (2011) L. Moreira-Teixeira et al. JOURNAL OF IMMUNOLOGY
- Translational Control of NKT Cell Cytokine Production by p38 MAPK
- (2011) Viswas K. Nagaleekar et al. JOURNAL OF IMMUNOLOGY
- Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals
- (2011) Patrick J Brennan et al. NATURE IMMUNOLOGY
- Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria
- (2011) Yuki Kinjo et al. NATURE IMMUNOLOGY
- Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses
- (2011) Pheh-Ping Chang et al. NATURE IMMUNOLOGY
- Induction of NKT cell-specific immune responses in cancer tissues after NKT cell-targeted adoptive immunotherapy
- (2010) Kazuki Yamasaki et al. CLINICAL IMMUNOLOGY
- Anti-tumor potential of type-I NKT cells against CD1d-positive and CD1d-negative tumors in humans
- (2010) Leonid S. Metelitsa CLINICAL IMMUNOLOGY
- Activating and inhibitory receptors of natural killer cells
- (2010) Hollie J Pegram et al. IMMUNOLOGY AND CELL BIOLOGY
- Invariant NKT cell anergy is induced by a strong TCR-mediated signal plus co-stimulation
- (2010) T. Iyoda et al. INTERNATIONAL IMMUNOLOGY
- Murine induced pluripotent stem cells can be derived from and differentiate into natural killer T cells
- (2010) Hiroshi Watarai et al. JOURNAL OF CLINICAL INVESTIGATION
- Antigen-Specific Cytotoxicity by Invariant NKT Cells In Vivo Is CD95/CD178-Dependent and Is Correlated with Antigenic Potency
- (2010) G. Wingender et al. JOURNAL OF IMMUNOLOGY
- Invariant NKT cells modulate the suppressive activity of IL-10-secreting neutrophils differentiated with serum amyloid A
- (2010) Carmela De Santo et al. NATURE IMMUNOLOGY
- Raising the NKT cell family
- (2010) Dale I Godfrey et al. NATURE IMMUNOLOGY
- A Comprehensive Ex Vivo Functional Analysis of Human NKT Cells Reveals Production of MIP1-α and MIP1-β, a Lack of IL-17, and a Th1-Bias in Males
- (2010) Jennifer E. Snyder-Cappione et al. PLoS One
- Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a -linked self-glycolipid
- (2010) P. Arrenberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Type I natural killer T cells suppress tumors caused by p53 loss in mice
- (2009) J. B. Swann et al. BLOOD
- Combination therapy ofin vitro-expanded natural killer T cells and α-galactosylceramide-pulsed antigen-presenting cells in patients with recurrent head and neck carcinoma
- (2009) Naoki Kunii et al. CANCER SCIENCE
- Immune characterization of an individual with an exceptionally high natural killer T cell frequency and her immediate family
- (2009) A. C. Chan et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Activating and inhibitory killer immunoglobulin-like receptors (KIR) in haploidentical haemopoietic stem cell transplantation to cure high-risk leukaemias
- (2009) A. Moretta et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Invariant NKT cells and CD1d+cells amass in human omentum and are depleted in patients with cancer and obesity
- (2009) Lydia Lynch et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Natural killer T cells in the lungs of patients with asthma
- (2009) Ponpan Matangkasombut et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Vα24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages
- (2009) Liping Song et al. JOURNAL OF CLINICAL INVESTIGATION
- Mechanisms for Glycolipid Antigen-Driven Cytokine Polarization by Vα14 i NKT Cells
- (2009) Barbara A. Sullivan et al. JOURNAL OF IMMUNOLOGY
- PD-1/PD-L Blockade Prevents Anergy Induction and Enhances the Anti-Tumor Activities of Glycolipid-Activated Invariant NKT Cells
- (2009) V. V. Parekh et al. JOURNAL OF IMMUNOLOGY
- A Phase I-II Study of -Galactosylceramide-Pulsed IL-2/GM-CSF-Cultured Peripheral Blood Mononuclear Cells in Patients with Advanced and Recurrent Non-Small Cell Lung Cancer
- (2009) S. Motohashi et al. JOURNAL OF IMMUNOLOGY
- Enrichment of Human CD4+ V 24/V 11 Invariant NKT Cells in Intrahepatic Malignant Tumors
- (2009) G. Bricard et al. JOURNAL OF IMMUNOLOGY
- Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases
- (2009) B. Gao et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Inflammation-associated lysophospholipids as ligands for CD1d-restricted T cells in human cancer
- (2008) D. H. Chang et al. BLOOD
- Type I NKT cells protect (and type II NKT cells suppress) the host's innate antitumor immune response to a B-cell lymphoma
- (2008) G. J. Renukaradhya et al. BLOOD
- Restoration of Tumor Immunosurveillance via Targeting of Interleukin-13 Receptor- 2
- (2008) S. Fichtner-Feigl et al. CANCER RESEARCH
- Tumor-derived soluble MICs impair CD3+CD56+ NKT-like cell cytotoxicity in cancer patients
- (2008) H WANG et al. IMMUNOLOGY LETTERS
- Sustained activation and tumor targeting of NKT cells using a CD1d–anti-HER2–scFv fusion protein induce antitumor effects in mice
- (2008) Kathrin Stirnemann et al. JOURNAL OF CLINICAL INVESTIGATION
- Impact of bacteria on the phenotype, functions, and therapeutic activities of invariant NKT cells in mice
- (2008) Sungjune Kim et al. JOURNAL OF CLINICAL INVESTIGATION
- A novel subset of NK cells expressing high levels of inhibitory FcγRIIB modulating antibody-dependent function
- (2008) Charles-Antoine Dutertre et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population
- (2008) J. M. Coquet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NK T cells provide lipid antigen-specific cognate help for B cells
- (2008) E. A. Leadbetter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- B cell receptor-mediated uptake of CD1d-restricted antigen augments antibody responses by recruiting invariant NKT cell help in vivo
- (2008) P. Barral et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NKG2D ligands: key targets of the immune response
- (2008) Segundo González et al. TRENDS IN IMMUNOLOGY
- Innate Invariant NKT Cells Recognize Mycobacterium tuberculosis–Infected Macrophages, Produce Interferon-γ, and Kill Intracellular Bacteria
- (2008) Isabel Sada-Ovalle et al. PLoS Pathogens
- Role of NKT cells in the digestive system. IV. The role of canonical natural killer T cells in mucosal immunity and inflammation
- (2007) Gerhard Wingender et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
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